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Volumn 76, Issue 3, 2008, Pages 145-151

TIMP-2 disrupts FGF-2-induced downstream signaling pathways

Author keywords

Angiogenesis; FGF 2; Integrin 3 1; Shp 1; TIMP 2

Indexed keywords

ALPHA3 INTEGRIN; BLOCKING ANTIBODY; FIBROBLAST GROWTH FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; ORTHOVANADIC ACID; PROTEIN TYROSINE PHOSPHATASE SHP 1; SMALL INTERFERING RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 2; VERY LATE ACTIVATION ANTIGEN 3;

EID: 53849109150     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2008.07.003     Document Type: Article
Times cited : (47)

References (32)
  • 1
    • 0036800192 scopus 로고    scopus 로고
    • Metalloproteinase inhibitors: biological actions and therapeutic opportunities
    • Baker A.H., Edwards D.R., and Murphy G. Metalloproteinase inhibitors: biological actions and therapeutic opportunities. J. Cell Sci. 115 (2002) 3719-3727
    • (2002) J. Cell Sci. , vol.115 , pp. 3719-3727
    • Baker, A.H.1    Edwards, D.R.2    Murphy, G.3
  • 2
    • 30744479430 scopus 로고    scopus 로고
    • Angiogenesis in life, disease and medicine
    • Carmeliet P. Angiogenesis in life, disease and medicine. Nature 438 (2005) 932-936
    • (2005) Nature , vol.438 , pp. 932-936
    • Carmeliet, P.1
  • 4
    • 0029035551 scopus 로고
    • Tissue inhibitor of metalloproteinase-2 stimulates fibroblast proliferation via a cAMP-dependent mechanism
    • Corcoran M.L., and Stetler-Stevenson W.G. Tissue inhibitor of metalloproteinase-2 stimulates fibroblast proliferation via a cAMP-dependent mechanism. J. Biol. Chem. 270 (1995) 13453-13459
    • (1995) J. Biol. Chem. , vol.270 , pp. 13453-13459
    • Corcoran, M.L.1    Stetler-Stevenson, W.G.2
  • 5
    • 0037192458 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors and cancer-trials and tribulations
    • Coussens L.M., Fingleton B., and Matrisian L.M. Matrix metalloproteinase inhibitors and cancer-trials and tribulations. Science 295 (2002) 2387-2392
    • (2002) Science , vol.295 , pp. 2387-2392
    • Coussens, L.M.1    Fingleton, B.2    Matrisian, L.M.3
  • 6
    • 0036236897 scopus 로고    scopus 로고
    • Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259
    • Dhillon A.S., Pollock C., Steen H., Shaw P.E., Mischak H., and Kolch W. Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259. Mol. Cell. Biol. 22 (2002) 3237-3246
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 3237-3246
    • Dhillon, A.S.1    Pollock, C.2    Steen, H.3    Shaw, P.E.4    Mischak, H.5    Kolch, W.6
  • 7
    • 0345617112 scopus 로고    scopus 로고
    • Structural and functional uncoupling of the enzymatic and angiogenic inhibitory activities of tissue inhibitor of metalloproteinase-2 (TIMP-2): LOOP 6 is a novel angiogenesis inhibitor
    • Fernandez C.A., Butterfield C., Jackson G., and Moses M.A. Structural and functional uncoupling of the enzymatic and angiogenic inhibitory activities of tissue inhibitor of metalloproteinase-2 (TIMP-2): LOOP 6 is a novel angiogenesis inhibitor. J. Biol. Chem. 278 (2003) 40989-40995
    • (2003) J. Biol. Chem. , vol.278 , pp. 40989-40995
    • Fernandez, C.A.1    Butterfield, C.2    Jackson, G.3    Moses, M.A.4
  • 8
    • 30744449235 scopus 로고    scopus 로고
    • Angiogenesis as a therapeutic target
    • Ferrara N., and Kerbel R.S. Angiogenesis as a therapeutic target. Nature 438 (2005) 967-974
    • (2005) Nature , vol.438 , pp. 967-974
    • Ferrara, N.1    Kerbel, R.S.2
  • 9
    • 9644289575 scopus 로고    scopus 로고
    • Integrins: versatile integrators of extracellular signals
    • FFrench-Constant C., and Colognato H. Integrins: versatile integrators of extracellular signals. Trends Cell Biol. 14 (2004) 678-686
    • (2004) Trends Cell Biol. , vol.14 , pp. 678-686
    • FFrench-Constant, C.1    Colognato, H.2
  • 10
  • 12
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D., and Weinberg R.A. The hallmarks of cancer. Cell 100 (2000) 57-70
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 13
    • 0035793638 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinases-2 (TIMP-2) suppresses TKR-growth factor signaling independent of metalloproteinase inhibition
    • Hoegy S.E., Oh H.-R., Corcoran M.L., and Stetler-Stevenson W.G. Tissue inhibitor of metalloproteinases-2 (TIMP-2) suppresses TKR-growth factor signaling independent of metalloproteinase inhibition. J. Biol. Chem. 276 (2001) 3203-3214
    • (2001) J. Biol. Chem. , vol.276 , pp. 3203-3214
    • Hoegy, S.E.1    Oh, H.-R.2    Corcoran, M.L.3    Stetler-Stevenson, W.G.4
  • 14
    • 33748371637 scopus 로고    scopus 로고
    • Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein
    • Jung K.K., Liu X.W., Chirco R., Fridman R., and Kim H.R. Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein. EMBO J. 25 (2006) 3934-3942
    • (2006) EMBO J. , vol.25 , pp. 3934-3942
    • Jung, K.K.1    Liu, X.W.2    Chirco, R.3    Fridman, R.4    Kim, H.R.5
  • 15
    • 0030706168 scopus 로고    scopus 로고
    • A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway
    • Kouhara H., Hadari Y.R., Spivak-Kroizman T., Schilling J., Bar-Sagi D., Lax I., and Schlessinger J. A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway. Cell 89 (1997) 693-702
    • (1997) Cell , vol.89 , pp. 693-702
    • Kouhara, H.1    Hadari, Y.R.2    Spivak-Kroizman, T.3    Schilling, J.4    Bar-Sagi, D.5    Lax, I.6    Schlessinger, J.7
  • 16
    • 20144379162 scopus 로고    scopus 로고
    • Endogenous inhibitors of angiogenesis
    • Nyberg P., Xie L., and Kalluri R. Endogenous inhibitors of angiogenesis. Cancer Res. 65 (2005) 3967-3979
    • (2005) Cancer Res. , vol.65 , pp. 3967-3979
    • Nyberg, P.1    Xie, L.2    Kalluri, R.3
  • 18
  • 19
    • 19044387522 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase-2 promotes neuronal differentiation by acting as an anti-mitogenic signal
    • Perez-Martinez L., and Jaworski D.M. Tissue inhibitor of metalloproteinase-2 promotes neuronal differentiation by acting as an anti-mitogenic signal. J. Neurosci. 25 (2005) 4917-4929
    • (2005) J. Neurosci. , vol.25 , pp. 4917-4929
    • Perez-Martinez, L.1    Jaworski, D.M.2
  • 20
    • 0037393850 scopus 로고    scopus 로고
    • A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2
    • Qi J.H., Ebrahem Q., Moore N., Murphy G., Claesson-Welsh L., Bond M., Baker A., and Anand-Apte B. A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2. Nat. Med. 9 (2003) 407-415
    • (2003) Nat. Med. , vol.9 , pp. 407-415
    • Qi, J.H.1    Ebrahem, Q.2    Moore, N.3    Murphy, G.4    Claesson-Welsh, L.5    Bond, M.6    Baker, A.7    Anand-Apte, B.8
  • 21
    • 0034927336 scopus 로고    scopus 로고
    • Regulation of phosphoinositide-specific phospholipase C
    • Rhee S.G. Regulation of phosphoinositide-specific phospholipase C. Annu. Rev. Biochem. 70 (2001) 281-312
    • (2001) Annu. Rev. Biochem. , vol.70 , pp. 281-312
    • Rhee, S.G.1
  • 22
    • 0034644539 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell 103 (2000) 211-225
    • (2000) Cell , vol.103 , pp. 211-225
    • Schlessinger, J.1
  • 23
    • 9444287030 scopus 로고    scopus 로고
    • Common and distinct elements in cellular signaling via EGF and FGF receptors
    • Schlessinger J. Common and distinct elements in cellular signaling via EGF and FGF receptors. Science 306 (2004) 1506-1507
    • (2004) Science , vol.306 , pp. 1506-1507
    • Schlessinger, J.1
  • 24
    • 0042203565 scopus 로고    scopus 로고
    • SH2 and PTB domains in tyrosine kinase signaling
    • Schlessinger J., and Lemmon M.A. SH2 and PTB domains in tyrosine kinase signaling. Sci. STKE 2003 (2003) re12
    • (2003) Sci. STKE , vol.2003
    • Schlessinger, J.1    Lemmon, M.A.2
  • 26
    • 33645646321 scopus 로고    scopus 로고
    • Shp-1 mediates the antiproliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial Cells
    • Seo D.-W., Li H., Qu C.-K., Oh J., Kim Y.-S., Diaz T., Wei B., Han J.-W., and Stetler-Stevenson W.G. Shp-1 mediates the antiproliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial Cells. J. Biol. Chem. 281 (2006) 3711-3721
    • (2006) J. Biol. Chem. , vol.281 , pp. 3711-3721
    • Seo, D.-W.1    Li, H.2    Qu, C.-K.3    Oh, J.4    Kim, Y.-S.5    Diaz, T.6    Wei, B.7    Han, J.-W.8    Stetler-Stevenson, W.G.9
  • 27
    • 0035188727 scopus 로고    scopus 로고
    • How matrix metalloproteinases regulate cell behavior
    • Sternlicht M.D., and Werb Z. How matrix metalloproteinases regulate cell behavior. Annu. Rev. Cell. Dev. Biol. 17 (2001) 463-516
    • (2001) Annu. Rev. Cell. Dev. Biol. , vol.17 , pp. 463-516
    • Sternlicht, M.D.1    Werb, Z.2
  • 28
    • 0033134622 scopus 로고    scopus 로고
    • Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention
    • Stetler-Stevenson W.G. Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention. J. Clin. Invest. 103 (1999) 1237-1241
    • (1999) J. Clin. Invest. , vol.103 , pp. 1237-1241
    • Stetler-Stevenson, W.G.1
  • 29
    • 14844284571 scopus 로고    scopus 로고
    • TIMP-2: an endogenous inhibitor of angiogenesis
    • Stetler-Stevenson W.G., and Seo D.-W. TIMP-2: an endogenous inhibitor of angiogenesis. Trends Mol. Med. 11 (2005) 97-103
    • (2005) Trends Mol. Med. , vol.11 , pp. 97-103
    • Stetler-Stevenson, W.G.1    Seo, D.-W.2
  • 30
    • 38549125513 scopus 로고    scopus 로고
    • The tumor microenvironment: regulation by MMP-independent effects of tissue inhibitor of metalloproteinases-2
    • Stetler-Stevenson W.G. The tumor microenvironment: regulation by MMP-independent effects of tissue inhibitor of metalloproteinases-2. Cancer Metastasis Rev. 27 (2008) 57-66
    • (2008) Cancer Metastasis Rev. , vol.27 , pp. 57-66
    • Stetler-Stevenson, W.G.1
  • 32
    • 0033597850 scopus 로고    scopus 로고
    • Biophysical and functional characterization of full-length, recombinant human tissue inhibitor of metalloproteinases-2 (TIMP-2) produced in Escherichia coli. Comparison of wild type and amino-terminal alanine appended variant with implications for the mechanism of TIMP functions
    • Wingfield P.T., Sax J.K., Stahl S.J., Kaufman J., Palmer I., Chung V., Corcoran M.L., Kleiner D.E., and Stetler-Stevenson W.G. Biophysical and functional characterization of full-length, recombinant human tissue inhibitor of metalloproteinases-2 (TIMP-2) produced in Escherichia coli. Comparison of wild type and amino-terminal alanine appended variant with implications for the mechanism of TIMP functions. J. Biol. Chem. 274 (1999) 21362-21368
    • (1999) J. Biol. Chem. , vol.274 , pp. 21362-21368
    • Wingfield, P.T.1    Sax, J.K.2    Stahl, S.J.3    Kaufman, J.4    Palmer, I.5    Chung, V.6    Corcoran, M.L.7    Kleiner, D.E.8    Stetler-Stevenson, W.G.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.