Efficacy of thiocolchicoside in Indian patients suffering from low back pain associated with muscle spasm

Journal of the Indian Medical Association

Volumn 106, Issue 5, 2008, Pages 331-335

  Soonawalla, Darius F ^a,b,c,d,e,f   Joshi, Niteen ^g  

^a BREACH CANDY HOSPITAL   (India)

^b JASLOK HOSPITAL AND RESEARCH CENTRE   (India)

^c Parsi General Hospital   (India)

^d SAIFEE HOSPITAL   (India)

^e Masina Hospital   (India)

^f Soonwalla Orthopaedics Clinic   (India)

^g Medley Pharmaceuticals Limited   (India)

Author keywords

Low back pain; Muscle spasm; Thiocolchicoside; Tizanidine

Indexed keywords

PARACETAMOL; THIOCOLCHICOSIDE; TIZANIDINE;

ADD ON THERAPY; ADULT; AGED; ALERTNESS; ANALGESIA; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; DIZZINESS; DROWSINESS; DRUG EFFICACY; DRUG SAFETY; FATIGUE; FEMALE; FOLLOW UP; HUMAN; INDIAN; LOW BACK PAIN; MAJOR CLINICAL STUDY; MALE; MEDICAL PARAMETERS; MUSCLE SPASM; PAIN ASSESSMENT; RANDOMIZED CONTROLLED TRIAL; SELF CONCEPT; SIDE EFFECT; SINGLE BLIND PROCEDURE; TREATMENT DURATION; VISUAL ANALOG SCALE;

EID: 53849101814     PISSN: 00195847     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Gorska J - Effects of back pain treatment with tizanidine. Orthop Traumatol Rehabil 2005; 7: 306-9.
2. Ketency A, Ozcan E - Assessment of efficacy and psychomotor performance of thiocolchicoside and tizanidine in patients with acute low back pain, Int J Clin Pract 2005; 59: 764-70.
3. Farkas S, Tarnawa I - Simple pharmacological test battery to assess efficacy and side effect profile of centrally acting muscle relaxants. J Pharmacol Toxicol Methods 2005; 52: 264-73.
4. Marcel C, Rezvani Y, Revel M - Evaluation of thiocolchicoside as monotherapy in low back pain: results of randomized study vs placebo (Eng Abstr). Presse Med 1990; 24: 1133-6.
5. Patat A, Klein MJ - Effects of acute and repeated doses of 2 SMRs chlormezanone and thiocolchicoside on vigilance and psychomotor performance of healthy volunteers. Hum Psychopharmacol 1991; 6: 285-6.
6. Trellu M, Filali-Ansary A, Françon D, Adam R, Lluel P, Dubruc C, et al - New metabolite and pharmacokinctic characteristics of thiocolchicoside and its active metabolite in healthy humans. Fundam Clin Pharmacol 2004; 18: 493-501.
7. Hennies OL - A new skeletal muscle relaxant (DS 103-282) compared to diazepam in the treatment of muscle spasm of local origin. J Intern Med Res 1981; 9: 62-8.
8. Coward DM - Tizanidine: neuropharmacology and mechanism of action. Neurology 1994; 44: S6-10
9. Smith H, Elliot J - Alpha 2 receptors and agonists in pain management. Curr Opin Anesthesiol 2001; 14: 513-8.
10. Gold RH - Orphenadrine citrate: sedative or muscle relaxant? Clin Ther 1978; 1: 451-3.
11. Lepisto P - A comparative trial of tizanidine and placebo in patients with skeletal muscle spasm after operation for herniated disk. Curr Ther Res 1981; 30: 141-6.
12. Janbroers JM - Review of the toxicology, pharmacodynamics and pharmacokinetics of thiocolchicoside, a GABA-agonist muscle relaxant with anti-inflammatory and analgesic actions. Acta Ther 1987; 13: 221-50.