XLA-associated neutropenia treatment: A case report and review of the literature

Journal of Pediatric Hematology/Oncology

Volumn 30, Issue 8, 2008, Pages 631-634

  Jacobs, Zachary David ^a   Guajardo, Jesus Ramon ^a,b,c   Anderson, Katherine Marie ^a  

^a University of Missouri   (United States)

^b Division of Allergy and Pulmonary   (United States)

^c UNIVERSITY OF MISSOURI   (United States)

Author keywords

Bruton's; Filgrastim; G CSF; Neupogen; Neutropenia; X linked agammaglobulinemia; XLA

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; CEFTRIAXONE; CEFUROXIME; DIPHTHERIA PERTUSSIS TETANUS VACCINE; HAEMOPHILUS INFLUENZAE TYPE B VACCINE; IMMUNOGLOBULIN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; SULTAMICILLIN; ANTIINFECTIVE AGENT;

ARTICLE; CASE REPORT; CHILD; COUGHING; DIAGNOSTIC TEST; DRUG SUBSTITUTION; DRUG WITHDRAWAL; EXPERIENCE; FEVER; GENE MUTATION; HEPATITIS B; HUMAN; IMMUNIZATION; IMMUNOPHENOTYPING; LUNG INFILTRATE; LUNG LAVAGE; LYMPH NODE; LYMPHOCYTE SUBPOPULATION; MALE; NEUTROPENIA; OXYGEN THERAPY; PNEUMONIA; PRESCHOOL CHILD; PRIORITY JOURNAL; RECURRENT DISEASE; RHINOSINUSITIS; TACHYPNEA; THORAX RADIOGRAPHY; TONSIL; X LINKED AGAMMAGLOBULINEMIA; AGAMMAGLOBULINEMIA; INFANT; KLEBSIELLA OXYTOCA; KLEBSIELLA PNEUMONIAE; LOBAR PNEUMONIA; PATHOPHYSIOLOGY; STREPTOCOCCUS PNEUMONIAE; X CHROMOSOME LINKED DISORDER;

AGAMMAGLOBULINEMIA; ANTI-BACTERIAL AGENTS; FILGRASTIM; GENETIC DISEASES, X-LINKED; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; INFANT; KLEBSIELLA OXYTOCA; KLEBSIELLA PNEUMONIAE; NEUTROPENIA; PNEUMONIA, PNEUMOCOCCAL; STREPTOCOCCUS PNEUMONIAE;

EID: 53749108372     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0b013e3181758947     Document Type: Article

References (27)

1. Bruton OC. Agammaglobulinemia. Pediatrics. 1952;9:722.
2. Ballow B, O'Neil K. Approach to the patient with recurrent infections. In: Adkinson NF, Yunginger JW, Busse WW, et al, eds. Middleton's Allergy: Principles and Practice. Philadelphia: Mosby; 2003: 1043-1072.
3. Rawlings DJ, Witte ON. Bruton's tyrosine kinase is a key regulator in B-cell development. Immun Rev. 1994;138:105-119.
4. Farrar JE, Rohrer J, Conley ME. Neutropenia in X-linked agammaglobulinemia. Clin Immunol Immunopathol. 1996;81:271-276.
5. Zsebo KM, Cohen AM, Murdock DC, et al. Recombinant human granulocyte colony-stimulating factor: molecular and biological characterization. Immunobiology. 1986;172:175-184.
6. Yuo A, Kitagawa S, Ohsaka A, et al. Recombinant human granulocyte colony-stimulating factor as an activator of human granulocytes: potentiation of responses triggered by receptormediated agonists and stimulation of C3bi receptor expression and adherence. Blood. 1989;74:2144-2149.
7. Bronchud MH, Scarffe JH, Thatcher N, et al. Phase I/II study of recombinant human granulocyte colony-stimulating factor in patients receiving intensive chemotherapy for small cell lung cancer. Brit J Cancer. 1987;56:809-813.
8. Gabrilove JL, Jakubowski A, Scher H, et al. Effect of granulocyte colony-stimulating factor on neutropenia and associated morbidity due to chemotherapy for transitional cell carcinoma of the urothelium. New Engl J Med. 1988;318:1414-1422.
9. Dale DC, Bonilla MA, Davis MW, et al. A randomized controlled phase III trial of recombinant human granulocyte colony-stimulating factor (filgrastim) for treatment of severe chronic neutropenia. Blood. 1993;81:2496-2502.
10. Dale DC, Cottle TE, Fier CJ, et al. Severe chronic neutropenia: treatment and follow-up of patients in the severe chronic neutropenia international registry. Am J Hematol. 2003;72:82-93.
11. Watts RG. Neutropenia. In: Greer JP, Rodgers GM, Foerster J, et al, eds. Wintrobe's Clinical Hematology. New York: Lippincott William & Wilkins; 2004:1778.
12. Kobayashi S, Tsutomu T, Saito M. Mutations of the Btk gene in 12 unrelated families with X-linked agammaglobulinemia in Japan. Hum Genet. 1996;97:424-430.
13. Lederman HM, Wikelstein JA. X-linked agammaglobulinemia: an analysis of 96 patients. Medicine. 1985;64:145-156.
14. Kozlowski C, Evans DIK. Neutropenia associated with X-linked agammaglobulinemia. J Clin Pathol. 1991;44:388-390.
15. Tavil B, Sipahi T. Is neutropenia a clue for early diagnosis of X-linked agammaglobulinemia? Pediatr Hematol Oncol. 2003;20: 657-658.
16. Kanegane H, Taneichi H, Nomura K, et al. Severe neutropenia in Japanese patients with X-linked agammaglobulinemia. J Clin Immunol. 2005;25:491-495.
17. Winkelstein JA, Marino MC, Lederman HM, et al. X-linked agammaglobulinemia: report on a United States registry of 201 patients. Medicine. 2006;85:193-202.
18. Amoras AL, Kanegane H, Miyawaki T, et al. Defective Fc, CR1 and CR3-mediated monocyte phagocytosis and chemotaxis in common variable immunodeficiency and X-linked agammaglobulinemia patients. J Invest Allergol Clin Immunol. 2003;13:181-188.
19. Horwood NJ, Mahon T, McDaid JP, et al. Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor a production. J Exp Med. 2003;197:1603-1611.
20. Scott CS. Maturation-linked expression of the Fc (IgG) receptor on developing human bone marrow and peripheral blood granulocytes. Clin Exp Immunol. 1979;38:300-305.
21. Leung BP, Culshaw S, Gracie JA, et al. A role for IL-18 in neutrophil activation. J Immunol. 2001;167:2879-2886.
22. Binstadt BA, Raif SG, Francisco AB. IgG Fc receptor polymorphisms in human disease: implications for intravenous immunoglobulin therapy. J Allergy Clin Immunol. 2003;111:697-703.
23. Ravetch JV, Bolland S. IgG Fc receptors. Annu Rev Immunol.2001;19: 275-290.
24. Valiaho J, Smith CI, Vihinen M. BTKbase: the mutation database for X-Linked agammaglobulinemia. Hum Mutat. 2006;27: 1209-1217.
25. Lindvall JM, Blomberg KEM, Väliaho J, et al. Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling. Immun Rev. 2005;203: 200-215.
26. Hartmann LC, Tschetter LK, Habermann TM, et al. Granulocyte colony-stimulating factor in severe chemotherapy-induced afebrile neutropenia. N Engl J Med. 1997;336:1776-1780.
27. Filgrastim: pediatric drug information. In: Lexi-Comp Online. Hudson, Ohio: Lexi-Comp Inc, 2007.