Modulation of key signal transduction molecules by a novel peptide combination effective for the treatment of gastrointestinal carcinomas

Investigational New Drugs

Volumn 26, Issue 6, 2008, Pages 505-516

  Singh, Anu T ^a   Jaggi, Manu ^a   Prasad, Sudhanand ^a   Dutt, Sarjana ^a   Singh, Gurvinder ^a   Datta, Kakali ^a   Rajendran, Praveen ^a   Sanna, Vinod K ^a   Mukherjee, Rama ^a   Burman, Anand C ^a  

^a DABUR RESEARCH FOUNDATION   (India)

Author keywords

Gastrointestinal carcinomas; Neuropeptide; Programmed cell death; Signaling; Targeted drug

Indexed keywords

BOMBESIN; CASPASE 3; CYCLIC AMP; DRF 7295; EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEPTIDE DERIVATIVE; PROTEIN BCL 2; PROTEIN P53; SOMATOSTATIN; SUBSTANCE P; UNCLASSIFIED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG TARGETING; ENDOTHELIUM CELL; ENZYME INHIBITION; GASTROINTESTINAL CARCINOMA; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIC AMP; DOWN-REGULATION; DRUG COMBINATIONS; DRUG SCREENING ASSAYS, ANTITUMOR; EPIDERMAL GROWTH FACTOR; GASTROINTESTINAL NEOPLASMS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PEPTIDES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 53749105337     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10637-008-9119-2     Document Type: Article

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