Functions of varicella-zoster virus ORF23 capsid protein in viral replication and the pathogenesis of skin infection

Journal of Virology

Volumn 82, Issue 20, 2008, Pages 10231-10246

  Chaudhuri, Vaishali ^a   Sommer, Marvin ^a   Rajamani, Jaya ^a   Zerboni, Leigh ^a   Arvin, Ann M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; CARRIER PROTEIN; HYBRID PROTEIN; MONOMER; PROTEIN VP26; RED FLUORESCENT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CARBOXY TERMINAL SEQUENCE; CELL LINE; GENOME ANALYSIS; HERPES VIRUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR TRANSPORT; MELANOMA CELL; MOUSE; MUTAGENESIS; NONHUMAN; NUCLEAR IMPORT; NUCLEAR LOCALIZATION SIGNAL; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN TRANSPORT; SEQUENCE HOMOLOGY; SKIN GRAFT; SKIN INFECTION; VARICELLA ZOSTER VIRUS; VIRUS CAPSID; VIRUS GENOME; VIRUS PATHOGENESIS; VIRUS REPLICATION; XENOGRAFT; ANIMAL; GENETICS; HERPES VIRUS INFECTION; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SKIN TRANSPLANTATION; VIROLOGY; VIRUS ASSEMBLY;

BACTERIA (MICROORGANISMS); HERPESVIRIDAE; HUMAN HERPESVIRUS 3; MIRIDAE;

ANIMALS; CAPSID; CAPSID PROTEINS; CELL LINE; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 3, HUMAN; HUMANS; MICE; OPEN READING FRAMES; RECOMBINANT FUSION PROTEINS; SKIN DISEASES, INFECTIOUS; SKIN TRANSPLANTATION; TRANSPLANTATION, HETEROLOGOUS; VIRUS ASSEMBLY; VIRUS REPLICATION;

EID: 53749105230     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01890-07     Document Type: Article

References (25)

1. Booy, F. P., B. L. Trus, W. W. Newcomb, J. C. Brown, J. F. Conway, and A. C. Steven. 1994. Finding a needle in a haystack: detection of a small protein (the 12-kDa VP26) in a large complex (the 200-MDa capsid of herpes simplex virus). Proc. Natl. Acad. Sci. USA 91:5652-5656.
2. Borst, E. M., S. Mathys, M. Wagner, W. Muranyi, and M. Messerle. 2001. Genetic evidence of an essential role for cytomegalovirus small capsid protein in viral growth. J. Virol. 75:1450-1458.
3. Cohen, G. H., M. Ponce de Leon, H. Diggelmann, W. C. Lawrence, S. K. Vernon, and R. J. Eisenberg. 1980. Structural analysis of the capsid polypeptides of herpes simplex virus types 1 and 2. J. Virol. 34:521-531.
4. Cohen, J. I., S. E. Straus, and A. M. Arvin. 2007. Varicella-zoster virus, p. 2773-2818. In D. H. Knipe, D. E. Griffin, R. A. Lamb, S. E. Straus, P. M. Howley, M. A. Martin, and B. Roizman (ed.), Fields virology, 5th ed. Lippincott Williams & Wilkins, Philadelphia, PA.
5. del Rio, T., T. H. Ch'ng, E. A. Flood, S. P. Gross, and L. W. Enquist. 2005. Heterogeneity of a fluorescent tegument component in single pseudorabies virus virions and enveloped axonal assemblies. J. Virol. 79:3903-3919.
6. Desai, P., J. C. Akpa, and S. Person. 2003. Residues of VP26 of herpes simplex virus type 1 that are required for its interaction with capsids. J. Virol. 77:391-404.
7. Desai, P., N. A. DeLuca, and S. Person. 1998. Herpes simplex virus type 1 VP26 is not essential for replication in cell culture but influences production of infectious virus in the nervous system of infected mice. Virology 247:115-124.
8. Desai, P., and S. Person. 1998. Incorporation of the green fluorescent protein into the herpes simplex virus type 1 capsid. J. Virol. 72:7563-7568.
9. Gibson, W., and B. Roizman. 1972. Proteins specified by herpes simplex virus. 8. Characterization and composition of multiple capsid forms of subtypes 1 and 2. J. Virol. 10:1044-1052.
10. Kut, E., and D. Rasschaert. 2004. Assembly of Marek's disease virus (MDV) capsids using recombinant baculoviruses expressing MDV capsid proteins. J. Gen. Virol. 85:769-774.
11. Lai, L., and W. J. Britt. 2003. The interaction between the major capsid protein and the smallest capsid protein of human cytomegalovirus is dependent on two linear sequences in the smallest capsid protein. J. Virol. 77:2730-2735.
12. Mallory, S., M. Sommer, and A. M. Arvin. 1998. Analysis of the glycoproteins I and E of varicella-zoster virus (VZV) using deletional mutations of VZV cosmids. J. Infect. Dis. 178(Suppl. 1):S22-S26.
13. McNabb, D. S., and R. J. Courtney. 1992. Identification and characterization of the herpes simplex virus type 1 virion protein encoded by the UL35 open reading frame. J. Virol. 66:2653-2663.
14. + T lymphocytes and epidermal cells in SCID-hu mice. J. Virol. 69:5236-5242.
15. Newcomb, W. W., B. L. Trus, F. P. Booy, A. C. Steven, J. S. Wall, and J. C. Brown. 1993. Structure of the herpes simplex virus capsid. Molecular composition of the pentons and the triplexes. J. Mol. Biol. 232:499-511.
16. Nicholson, P., C. Addison, A. M. Cross, J. Kennard, V. G. Preston, and F. J. Rixon. 1994. Localization of the herpes simplex virus type 1 major capsid protein VP5 to the cell nucleus requires the abundant scaffolding protein VP22a. J. Gen. Virol. 75:1091-1099.
17. Niizuma, T., L. Zerboni, M. H. Sommer, H. Ito, S. Hinchliffe, and A. M. Arvin. 2003. Construction of varicella-zoster virus recombinants from parent Oka cosmids and demonstration that ORF65 protein is dispensable for infection of human skin and T cells in the SCID-hu mouse model. J. Virol. 77:6062-6065.
18. Preston, V. G., J. Kennard, F. J. Rixon, A. J. Logan, R. W. Mansfield, and I. M. McDougall. 1997. Efficient herpes simplex virus type 1 (HSV-1) capsid formation directed by the varicella-zoster virus scaffolding protein requires the carboxy-terminal sequences from the HSV-1 homologue. J. Gen. Virol. 78:1633-1646.
19. Rixon, F. J., C. Addison, A. McGregor, S. J. Macnab, P. Nicholson, V. G. Preston, and J. D. Tatman. 1996. Multiple interactions control the intracellular localization of the herpes simplex virus type 1 capsid proteins. J. Gen. Virol. 77:2251-2260.
20. Sheaffer, A. K., W. W. Newcomb, J. C. Brown, M. Gao, S. K. Weller, and D. J. Tenney. 2000. Evidence for controlled incorporation of herpes simplex virus type 1 UL26 protease into capsids. J. Virol. 74:6838-6848.
21. Sommer, M. H., E. Zagha, O. K. Serrano, C. C. Ku, L. Zerboni, A. Baiker, R. Santos, M. Spengler, J. Lynch, C. Grose, W. Ruyechan, J. Hay, and A. M. Arvin. 2001. Mutational analysis of the repeated open reading frames, ORFs 63 and 70 and ORFs 64 and 69, of varicella-zoster virus. J. Virol. 75:8224-8239.
22. Spencer, J. V., W. W. Newcomb, D. R. Thomsen, F. L. Homa, and J. C. Brown. 1998. Assembly of the herpes simplex virus capsid: preformed triplexes bind to the nascent capsid. J. Virol. 72:3944-3951.
23. Tischer, B. K., J. von Einem, B. Kaufer, and N. Osterrieder. 2006. Two-step red-mediated recombination for versatile high-efficiency markerless DNA manipulation in Escherichia coli. BioTechniques 40:191-197.
24. Trus, B. L., W. W. Newcomb, F. P. Booy, J. C. Brown, and A. C. Steven. 1992. Distinct monoclonal antibodies separately label the hexons or the pentons of herpes simplex virus capsid. Proc. Natl. Acad. Sci. USA 89:11508-11512.
25. Zhou, Z. H., J. He, J. Jakana, J. D. Tatman, F. J. Rixon, and W. Chiu. 1995. Assembly of VP26 in herpes simplex virus-1 inferred from structures of wild-type and recombinant capsids. Nat. Struct. Biol. 2:1026-1030.