Smoothelin-B deficiency results in reduced arterial contractility, hypertension, and cardiac hypertrophy in mice

Circulation

Volumn 118, Issue 8, 2008, Pages 828-836

  Rensen, Sander S ^a   Niessen, Petra M ^a   Van Deursen, Jan M ^b   Janssen, Ben J ^a   Heijman, Edwin ^c   Hermeling, Evelien ^a   Meens, Merlijn ^a   Lie, Natascha ^a   Gijbels, Marion J ^a   Strijkers, Gustav J ^a,c   Doevendans, Pieter A ^a   Hofker, Marten H ^a   De Mey, Jo G R ^a   Van Eys, Guillaume J ^a,d  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAYO CLINIC   (United States)

^c EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

^d MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Hypertension; Hypertrophy; Muscle; Muscle contraction; Smooth; Vascular resistance

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ATROPINE; CALPONIN; METOPROLOL; MYOSIN HEAVY CHAIN ALPHA; PRAZOSIN; SMOOTHELIN; SMOOTHELIN B; UNCLASSIFIED DRUG; YOHIMBINE; CYTOSKELETON PROTEIN; MUSCLE PROTEIN; SMTN PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY; ARTERY DILATATION; ARTERY MUSCLE; ARTICLE; BLOOD PRESSURE REGULATION; BLOOD VESSEL FUNCTION; BODY WEIGHT; CONTROLLED STUDY; DRUG RESPONSE; FEMORAL ARTERY; GENE EXPRESSION; GENE MUTATION; HEART CYCLE; HEART FUNCTION; HEART OUTPUT; HEART RATE; HEART STROKE VOLUME; HEART VENTRICLE HYPERTROPHY; HEART WEIGHT; HYPERTENSION; MALE; MEAN ARTERIAL PRESSURE; MOUSE; MOUSE MUTANT; MUSCLE LEVEL; MYOGRAPHY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PARASYMPATHETIC TONE; PHENOTYPE; PRIORITY JOURNAL; PULSE PRESSURE; PULSE WAVE; SAPHENOUS ARTERY; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE FIBER; SYMPATHETIC TONE; THORACIC AORTA; VASCULAR RESISTANCE; ANIMAL; CARDIOMEGALY; PHYSIOLOGY; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION;

ANIMALS; ARTERIES; CARDIOMEGALY; CYTOSKELETAL PROTEINS; HYPERTENSION; MICE; MICE, KNOCKOUT; MUSCLE PROTEINS; MUSCLE, SMOOTH, VASCULAR; VASCULAR RESISTANCE; VASOCONSTRICTION;

EID: 53749095130     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.107.743690     Document Type: Article

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