|
Volumn 27, Issue 3, 2008, Pages 233-243
|
Insight into the structural requirements of proton pump inhibitors based on CoMFA and CoMSIA studies
|
Author keywords
3D QSAR; CoMFA; CoMSIA; Gastric (H+ K+) ATPase; Proton pump inhibitors
|
Indexed keywords
KETONES;
3D-QSAR;
COMFA;
COMSIA;
GASTRIC (H+/K+)-ATPASE;
PROTON PUMP INHIBITORS;
THREE DIMENSIONAL;
ADENOSINE TRIPHOSPHATASE;
POTASSIUM ION;
PROTON;
PROTON PUMP INHIBITOR;
QUINAZOLINE DERIVATIVE;
QUINOLINE DERIVATIVE;
ARTICLE;
BINDING AFFINITY;
BIOLOGICAL ACTIVITY;
CALCULATION;
COMPARATIVE MOLECULAR FIELD ANALYSIS;
COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS;
DRUG ACTIVITY;
DRUG BINDING;
DRUG STRUCTURE;
ELECTRIC FIELD;
EXPERIMENTAL MODEL;
MOLECULAR MODEL;
PREDICTION;
PRIORITY JOURNAL;
QUANTITATIVE STRUCTURE ACTIVITY RELATION;
VALIDATION STUDY;
H(+)-K(+)-EXCHANGING ATPASE;
HYDROGEN BONDING;
HYDROPHOBICITY;
MODELS, MOLECULAR;
PROTON PUMP INHIBITORS;
QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;
REPRODUCIBILITY OF RESULTS;
STATIC ELECTRICITY;
|
EID: 53749084902
PISSN: 10933263
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jmgm.2008.04.012 Document Type: Article |
Times cited : (7)
|
References (30)
|