Constitutive histamine H2 receptor activity regulates serotonin release in the substantia nigra

Journal of Neurochemistry

Volumn 107, Issue 3, 2008, Pages 745-755

  Threlfell, Sarah ^a,b   Exley, Richard ^a   Cragg, Stephanie J ^a   Greenfield, Susan A ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

Author keywords

5 hydroxytryptamine; Basal ganglia; Fast scan cyclic voltammetry; Histamine; Parkinson's disease; Substantia nigra pars reticulata

Indexed keywords

4 AMINOBUTYRIC ACID; 5 HYDROXYTRYPTOPHAN; BURIMAMIDE; HISTAMINE H2 RECEPTOR; RANITIDINE; SEROTONIN; HISTAMINE AGONIST; HISTAMINE H2 RECEPTOR ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; CONTROLLED STUDY; CYCLIC POTENTIOMETRY; DRUG EFFECT; DRUG INHIBITION; MALE; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; SEROTONIN RELEASE; SUBSTANTIA NIGRA; ANIMAL; METABOLISM; MICROELECTRODE; NERVE CELL; ORGAN CULTURE TECHNIQUE; PATCH CLAMP; SECRETION; WISTAR RAT;

RATTUS;

ANIMALS; HISTAMINE AGONISTS; HISTAMINE H2 ANTAGONISTS; MALE; MICROELECTRODES; NEURONS; ORGAN CULTURE TECHNIQUES; PATCH-CLAMP TECHNIQUES; RATS; RATS, WISTAR; RECEPTORS, HISTAMINE H2; SEROTONIN; SUBSTANTIA NIGRA;

EID: 53749084249     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05646.x     Document Type: Article

References (59)

1. Adachi N., Liu K. Arai T. (2005) Prevention of brain infarction by postischemic administration of histidine in rats. Brain Res. 1039, 220 223.
2. Aghajanian G. K. Vandermaelen C. P. (1982) Intracellular recordings from serotonergic dorsal raphe neurons: pacemaker potentials and the effect of LSD. Brain Res. 238, 463 469.
3. Alewijnse A. E., Smit M. J., Hoffmann M., Verzijl D., Timmerman H. Leurs R. (1998) Constitutive activity and structural instability of the wild-type human H2 receptor. J. Neurochem. 71, 799 807.
4. Alewijnse A. E., Timmerman H., Jacobs E. H., Smit M. J., Roovers E., Cotecchia S. Leurs R. (2000) The effect of mutations in the DRY motif on the constitutive activity and structural instability of the histamine H(2) receptor. Mol. Pharmacol. 57, 890 898.
5. Alexander G. E. Crutcher M. D. (1990) Functional architecture of basal ganglia circuits: neural substrates of parallel processing. Trends Neurosci. 13, 266 271.
6. Anichtchik O. V., Rinne J. O., Kalimo H. Panula P. (2000) An altered histaminergic innervation of the substantia nigra in Parkinson's disease. Exp. Neurol. 163, 20 30.
7. Anichtchik O. V., Peitsaro N., Rinne J. O., Kalimo H. Panula P. (2001) Distribution and modulation of histamine H(3) receptors in basal ganglia and frontal cortex of healthy controls and patients with Parkinson's disease. Neurobiol. Dis. 8, 707 716.
8. Black J. W., Duncan W. A., Durant C. J., Ganellin C. R. Parsons E. M. (1972) Definition and antagonism of histamine H 2 -receptors. Nature 236, 385 390.
9. Brown R. E., Stevens D. R. Haas H. L. (2001) The physiology of brain histamine. Prog. Neurobiol. 63, 637 672.
10. Bunin M. A., Prioleau C., Mailman R. B. Wightman R. M. (1998) Release and uptake rates of 5-hydroxytryptamine in the dorsal raphe and substantia nigra reticulata of the rat brain. J. Neurochem. 70, 1077 1087.
11. Chen K., Zhu J. N., Li H. Z. Wang J. J. (2003) Histamine elicits neuronal excitatory response of red nucleus in the rat via H2 receptors in vitro. Neurosci. Lett. 351, 25 28.
12. Chen K., Wang J. J., Yung W. H., Chan Y. S. Chow B. K. (2005) Excitatory effect of histamine on neuronal activity of rat globus pallidus by activation of H2 receptors in vitro. Neurosci. Res. 53, 288 297.
13. Cobb W. S. Abercrombie E. D. (2003) Differential regulation of somatodendritic and nerve terminal dopamine release by serotonergic innervation of substantia nigra. J. Neurochem. 84, 576 584.
14. Corvaja N., Doucet G. Bolam J. P. (1993) Ultrastructure and synaptic targets of the raphe-nigral projection in the rat. Neuroscience 55, 417 427.
15. Cragg S. J. Greenfield S. A. (1997) Differential autoreceptor control of somatodendritic and axon terminal dopamine release in substantia nigra, ventral tegmental area, and striatum. J. Neurosci. 17, 5738 5746.
16. Cragg S. J., Hawkey C. R. Greenfield S. A. (1997) Comparison of serotonin and dopamine release in substantia nigra and ventral tegmental area: region and species differences. J. Neurochem. 69, 2378 2386.
17. Di Matteo V., De Blasi A., Di Giulio C. Esposito E. (2001) Role of 5-HT(2C) receptors in the control of central dopamine function. Trends Pharmacol. Sci. 22, 229 232.
18. Esbenshade T. A., Kang C. H., Krueger K. M., Miller T. R., Witte D. G., Roch J. M., Masters J. N. Hancock A. A. (2003) Differential activation of dual signaling responses by human H1 and H2 histamine receptors. J. Recept. Signal Transduct. Res. 23, 17 31.
19. Garcia-Ramirez M., Aceves J. Arias-Montano J. A. (2004) Intranigral injection of the H3 agonist immepip and systemic apomorphine elicit ipsilateral turning behaviour in naive rats, but reduce contralateral turning in hemiparkinsonian rats. Behav. Brain Res. 154, 409 415.
20. Gartside S. E., Hajos-Korcsok E., Bagdy E., Harsing Jr. L. G., Sharp T. Hajos M. (2000) Neurochemical and electrophysiological studies on the functional significance of burst firing in serotonergic neurons. Neuroscience 98, 295 300.
21. Gomez-Ramirez J., Johnston T. H., Visanji N. P., Fox S. H. Brotchie J. M. (2006) Histamine H3 receptor agonists reduce L-dopa-induced chorea, but not dystonia, in the MPTP-lesioned nonhuman primate model of Parkinson's disease. Mov. Disord. 6, 839 846.
22. van der Goot H. Timmerman H. (2000) Selective ligands as tools to study histamine receptors. Eur. J. Med. Chem. 35, 5 20.
23. Haas H. L. Bucher U. M. (1975) Histamine H2-receptors on single central neurones. Nature 255, 634 635.
24. Haas H. L. Greene R. W. (1986) Effects of histamine on hippocampal pyramidal cells of the rat in vitro. Exp. Brain Res. 62, 123 130.
25. Haas H. L. Konnerth A. (1983) Histamine and noradrenaline decrease calcium-activated potassium conductance in hippocampal pyramidal cells. Nature 302, 432 434.
26. Haas H. L. Wolf P. (1977) Central actions of histamine: microelectrophoretic studies. Brain Res. 122, 269 279.
27. Hajos M. Sharp T. (1996a) A 5-hydroxytryptamine lesion markedly reduces the incidence of burst-firing dorsal raphe neurones in the rat. Neurosci. Lett. 204, 161 164.
28. Hajos M. Sharp T. (1996b) Burst-firing activity of presumed 5-HT neurones of the rat dorsal raphe nucleus: electrophysiological analysis by antidromic stimulation. Brain Res. 740, 162 168.
29. Hajos M., Gartside S. E., Villa A. E. Sharp T. (1995) Evidence for a repetitive (burst) firing pattern in a sub-population of 5-hydroxytryptamine neurons in the dorsal and median raphe nuclei of the rat. Neuroscience 69, 189 197.
30. Hajos M., Sharp T. Newberry N. R. (1996) Intracellular recordings from burst-firing presumed serotonergic neurones in the rat dorsal raphe nucleus in vivo. Brain Res. 737, 308 312.
31. Hamami G., Adachi N., Liu K. Arai T. (2004) Alleviation of ischemic neuronal damage by histamine H2 receptor stimulation in the rat striatum. Eur. J. Pharmacol. 484, 167 173.
32. Iravani M. M. Kruk Z. L. (1997) Real-time measurement of stimulated 5-hydroxytryptamine release in rat substantia nigra pars reticulata brain slices. Synapse 25, 93 102.
33. Jacobs B. L. Fornal C. A. (1993) 5-HT and motor control: a hypothesis. Trends Neurosci. 16, 346 352.
34. John C. E., Budygin E. A., Mateo Y. Jones S. R. (2006) Neurochemical characterization of the release and uptake of dopamine in ventral tegmental area and serotonin in substantia nigra of the mouse. J. Neurochem. 96, 267 282.
35. Lakoski J. M. Aghajanian G. K. (1983) Effects of histamine, H1- and H2-receptor antagonists on the activity of serotonergic neurons in the dorsal raphe nucleus. J. Pharmacol. Exp. Ther. 227, 517 523.
36. Lefkowitz R. J., Cotecchia S., Samama P. Costa T. (1993) Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins. Trends Pharmacol. Sci. 14, 303 307.
37. Malagelada C., Xifro X., Badiola N., Sabria J. Rodriguez-Alvarez J. (2004) Histamine H2-receptor antagonist ranitidine protects against neural death induced by oxygen-glucose deprivation. Stroke 35, 2396 2401.
38. Meltzer H. (1989) Serotonergic dysfunction in depression. Br. J. Psychiatry Suppl., 8, 25 31.
39. Monczor F., Legnazzi B. L., Rivera E. Davio C. (1998) Tiotidine, a classical H2-antagonist, presents characteristics of an inverse agonist in U937 cell line. Inflamm. Res. 47 (Suppl 1 S42 S43.
40. Monczor F., Fernandez N., Legnazzi B. L., Riveiro M. E., Baldi A., Shayo C. Davio C. (2003) Tiotidine, a histamine H2 receptor inverse agonist that binds with high affinity to an inactive G-protein-coupled form of the receptor. Experimental support for the cubic ternary complex model. Mol. Pharmacol. 64, 512 520.
41. Morisset S., Rouleau A., Ligneau X., Gbahou F., Tardivel-Lacombe J., Stark H., Schunack W., Ganellin C. R., Schwartz J. C. Arrang J. M. (2000) High constitutive activity of native H3 receptors regulates histamine neurons in brain. Nature 408, 860 864.
42. Moukhles H., Bosler O., Bolam J. P., Vallee A., Umbriaco D., Geffard M. Doucet G. (1997) Quantitative and morphometric data indicate precise cellular interactions between serotonin terminals and postsynaptic targets in rat substantia nigra. Neuroscience 76, 1159 1171.
43. Nicholson S. L. Brotchie J. M. (2002) 5-hydroxytryptamine (5-HT, serotonin) and Parkinson's disease - opportunities for novel therapeutics to reduce the problems of levodopa therapy. Eur. J. Neurol. 9 (Suppl 3 1 6.
44. Oda T. Matsumoto S. (2001) Identification and characterization of histamine H4 receptor. Nippon Yakurigaku Zasshi 118, 36 42.
45. Panula P., Pirvola U., Auvinen S. Airaksinen M. S. (1989) Histamine-immunoreactive nerve fibers in the rat brain. Neuroscience 28, 585 610.
46. Paxinos G. Watson C. (1982) The Rat Brain in Stereotaxic Coordinates. Academic Press, San Diego.
47. Pillot C., Heron A., Cochois V., Tardivel-Lacombe J., Ligneau X., Schwartz J. C. Arrang J. M. (2002) A detailed mapping of the histamine H(3) receptor and its gene transcripts in rat brain. Neuroscience 114, 173 193.
48. Poli E., Todorov S., Pozzoli C. Bertaccini G. (1994) Presynaptic histamine H2 receptors modulate the sympathetic nerve transmission in the isolated rat vas deferens; no role for H3-receptors. Agents Actions 42, 95 100.
49. Prast H., Tran M. H., Lamberti C., Fischer H., Kraus M., Grass K. Philippu A. (1999) Histaminergic neurons modulate acetylcholine release in the ventral striatum: role of H1 and H2 histamine receptors. Naunyn Schmiedebergs Arch. Pharmacol. 360, 552 557.
50. Rice M. E. Nicholson C. (1989) Measurement of nanomolar dopamine diffusion using low-noise perfluorinated ionomer coated carbon fiber microelectrodes and high-speed cyclic voltammetry. Anal. Chem. 61, 1805 1810.
51. Rick C. E., Stanford I. M. Lacey M. G. (1995) Excitation of rat substantia nigra pars reticulata neurons by 5-hydroxytryptamine in vitro: evidence for a direct action mediated by 5-hydroxytryptamine2C receptors. Neuroscience 69, 903 913.
52. Smit M. J., Leurs R., Alewijnse A. E., Blauw J., Van Nieuw Amerongen G. P., Van De Vrede Y., Roovers E. Timmerman H. (1996) Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptors. Proc. Natl Acad. Sci. USA 93, 6802 6807.
53. Stanford I. M. Lacey M. G. (1996) Differential actions of serotonin, mediated by 5-HT1B and 5-HT2C receptors, on GABA-mediated synaptic input to rat substantia nigra pars reticulata neurons in vitro. J. Neurosci. 16, 7566 7573.
54. Thomson A. M. (2000) Molecular frequency filters at central synapses. Prog. Neurobiol. 62, 159 196.
55. Threlfell S., Cragg S. J., Kallo I., Turi G. F., Coen C. W. Greenfield S. A. (2004) Histamine H3 receptors inhibit serotonin release in substantia nigra pars reticulata. J. Neurosci. 24, 8704 8710.
56. Timm J., Marr I., Werthwein S., Elz S., Schunack W. Schlicker E. (1998) H2 receptor-mediated facilitation and H3 receptor-mediated inhibition of noradrenaline release in the guinea-pig brain. Naunyn Schmiedebergs Arch. Pharmacol. 357, 232 239.
57. Venton B. J., Michael D. J. Wightman R. M. (2003) Correlation of local changes in extracellular oxygen and pH that accompany dopaminergic terminal activity in the rat caudate-putamen. J. Neurochem. 84, 373 381.
58. Vizuete M. L., Traiffort E., Bouthenet M. L., Ruat M., Souil E., Tardivel-Lacombe J. Schwartz J. C. (1997) Detailed mapping of the histamine H2 receptor and its gene transcripts in guinea-pig brain. Neuroscience 80, 321 343.
59. Zhou F. W., Xu J. J., Zhao Y., LeDoux M. S. Zhou F. M. (2006) Opposite functions of histamine H1 and H2 receptors and H3 receptor in substantia nigra pars reticulata. J. Neurophysiol. 96, 1581 1591.