Catastrophic graft-versus-host disease after lung transplantation proven by PCR-based chimerism analysis

Transplant International

Volumn 21, Issue 11, 2008, Pages 1098-1101

  Worel, Nina ^a   Bojic, Andja ^a   Binder, Michael ^b   Jaksch, Peter ^a   Mitterbauer, Gerlinde ^a   Streubel, Berthold ^a   Thalhammer, Florian ^a   Staudinger, Thomas ^a   Laczika, Klaus F ^a   Locker, Gottfried J ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b Universitatsklinik fur Dermatologie   (Austria)

Author keywords

Chimerism analysis; Graft versus host disease; Lung transplantation

Indexed keywords

BASILIXIMAB; COTRIMOXAZOLE; CYCLOSPORIN A; GRANULOCYTE COLONY STIMULATING FACTOR; IMMUNOSUPPRESSIVE AGENT; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; TACROLIMUS; VALACICLOVIR;

ACUTE GRAFT VERSUS HOST DISEASE; ADULT; ARTICLE; BONE MARROW APLASIA; BONE MARROW BIOPSY; BONE MARROW DEPRESSION; CASE REPORT; CEREBRAL MICROANGIOPATHY; CHRONIC OBSTRUCTIVE LUNG DISEASE; DIARRHEA; DIFFERENTIAL DIAGNOSIS; DRUG DOSE INCREASE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; ENTEROPATHY; ERYTHEMA; FEMALE; FEVER; GASTROINTESTINAL HEMORRHAGE; GRAFT VERSUS HOST REACTION; HUMAN; HYPERBILIRUBINEMIA; IMMUNOSUPPRESSIVE TREATMENT; LIVER DISEASE; LUNG TRANSPLANTATION; MACULOPAPULAR RASH; MICROANGIOPATHY; MULTIPLE ORGAN FAILURE; NEUTROPENIA; ORGAN TRANSPLANTATION; POLYMERASE CHAIN REACTION; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; SEIZURE; SKIN BIOPSY; SKIN EXFOLIATION;

FATAL OUTCOME; FEMALE; GRAFT VS HOST DISEASE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LUNG TRANSPLANTATION; MIDDLE AGED; MULTIPLE ORGAN FAILURE; POLYMERASE CHAIN REACTION; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; TRANSPLANTATION CHIMERA;

EID: 53749083955     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/j.1432-2277.2008.00754.x     Document Type: Article

References (20)

1. Deeg HJ, Storer BE, Boeckh M, et al. Reduced incidence of acute and chronic graft- -host disease with the addition of thymoglobulin to a targeted busulfan/cyclophosphamide regimen. Biol Blood Marrow Transplant 2006 12 : 573.
2. Dwyre DM, Holland PV. Transfusion-associated graft-versus-host disease. Vox Sang 2008 95 : 85.
3. Pfitzmann R, Hummel M, Grauhan O, et al. Acute graft-versus-host disease after human heart-lung transplantation: a case report. J Thorac Cardiovasc Surg 1997 114 : 285.
4. Luckraz H, Zagolin M, McNeil K, Wallwork J. Graft-versus-host disease in lung transplantation: 4 case reports and literature review. J Heart Lung Transplant 2002 22 : 691.
5. Gulbahace HE, Brown CA, Wick M, Segall M, Jessurun J. Graft-vs-host disease after solid organ transplant. Am J Clin Pathol 2003 119 : 568.
6. Kohler S, Pascher A, Junge G, et al. Graft versus host disease after liver transplantation - a single center experience and review of literature. Transpl Int 2008 21 : 441.
7. Glucksberg H, Storb R, Fefer A, et al. Clinical manifestations of graft-versus-host disease in human recipients of marrow from HL-A-matched sibling donors. Transplantation 1974 18 : 295.
8. Ko S, Dahlke MH, Lauth O, et al. Bone marrow aplasia induced by passenger leukocytes from heart allografts. Exp Hematol 2001 29 : 339.
9. Greinix HT, Knobler RM, Worel N, et al. The effect of intensified extracorporeal photochemotherapy on long-term survival in patients with severe acute graft-versus-host disease. Haematologica 2006 91 : 405.
10. Nollet F, Billiet J, Selleslag D, Criel A. Standardisation of multiplex fluorescent short tandem repeat analysis for chimerism testing. Bone Marrow Transplant 2001 28 : 511.
11. Taylor AL, Gibbs P, Sudhindran S, et al. Monitoring systemic donor lymphocyte macrochimerism to aid the diagnosis of graft-versus-host disease after liver transplantation. Transplantation 2004 77 : 441.
12. Smith DM, Agura E, Netto G, et al. Liver transplant-associated graft-versus-host disease. Transplantation 2003 75 : 118.
13. Assi MA, Pulido JS, Peters SG, McCannel CA, Razonable RR. Graft-vs.-host disease in lung and other solid organ transplant recipients. Clin Transplant 2007 21 : 1.
14. Trulock EP, Edwards LB, Taylor DO, Boucek MM, Keck BM, Hertz MI. The registry of the international society for heart and lung transplantation: twenty-first official adult lung and heart-transplant report-2004. J Heart Lung Transplant 2004 23 : 804.
15. Wy A, SK M, Kwong YL, et al. Graft-versus-host disease after liver transplantation: documentation by fluorescent in situ hybridisation and human leukocyte antigen typing. Clin Transplant 2000 14 : 174.
16. Meves A, el-Azhary RA, Talwalkar JA. Acute graft-versus-host disease after liver transplantation diagnosed by fluorescent in situ hybridization testing of skin biopsy specimens. J Am Acad Dermatol 2006 55 : 642.
17. Taylor AL, Gibbs P, Bradley JA. Acute graft versus host disease following liver transplantation: the enemy within. Am J Transplant 2004 4 : 466.
18. Van Lint MT, Uderzo C, Locasciulli A, et al. Early treatment of acute graft-versus-host disease with high or low-dose 6-methylprednisolone: a multicenter randomised trial from the Italian Group for Bone Marrow Transplantation. Blood 1998 92 : 2288.
19. Graziani F, Van Lint MT, Dominietto A, et al. Treatment of acute graft versus host disease with low dose-alternate day anti-thymocyte globulin. Haematologica 2002 87 : 973.
20. Schmidt-Hieber M, Fietz T, Knauf W, et al. Efficacy of the interleukin-2 receptor antagonist basiliximab in steroid-refractory acute graft-versus-host disease. Br J Haematol 2005 130 : 568.