메뉴 건너뛰기




Volumn 26, Issue 46, 2008, Pages 5814-5821

Chimeric hepatitis B virus core particles carrying an epitope of anthrax protective antigen induce protective immunity against Bacillus anthracis

Author keywords

Anthrax protective antigen; Anthrax vaccine; HBc particles; Neutralizing epitope

Indexed keywords

ALUMINUM POTASSIUM SULFATE; ANTHRAX TOXIN; ANTHRAX VACCINE; EPITOPE; FREUND ADJUVANT; HEPATITIS B CORE ANTIGEN; HEPATITIS B CORE ANTIGEN N144 PA LOOP2 PROTEIN; HEPATITIS B CORE ANTIGEN N144 PROTEIN; HYBRID PROTEIN; RECOMBINANT PROTECTIVE ANTIGEN; UNCLASSIFIED DRUG;

EID: 53649111582     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2008.08.031     Document Type: Article
Times cited : (25)

References (51)
  • 2
    • 0036022854 scopus 로고    scopus 로고
    • Introduction: anthrax history, disease and ecology
    • Turnbull P.C. Introduction: anthrax history, disease and ecology. Curr Top Microbiol Immunol 271 (2002) 1-19
    • (2002) Curr Top Microbiol Immunol , vol.271 , pp. 1-19
    • Turnbull, P.C.1
  • 4
    • 34447291354 scopus 로고    scopus 로고
    • Anthrax toxin: receptor binding, internalization, pore formation, and translocation
    • Young J.A., and Collier R.J. Anthrax toxin: receptor binding, internalization, pore formation, and translocation. Annu Rev Biochem 76 (2007) 243-265
    • (2007) Annu Rev Biochem , vol.76 , pp. 243-265
    • Young, J.A.1    Collier, R.J.2
  • 5
    • 0025868227 scopus 로고
    • Anthrax vaccines: past, present and future
    • Turnbull P.C. Anthrax vaccines: past, present and future. Vaccine 9 8 (1991) 533-539
    • (1991) Vaccine , vol.9 , Issue.8 , pp. 533-539
    • Turnbull, P.C.1
  • 6
    • 0034003059 scopus 로고    scopus 로고
    • Current status of immunization against anthrax: old vaccines may be here to stay for a while
    • Turnbull P.C. Current status of immunization against anthrax: old vaccines may be here to stay for a while. Curr Opin Infect Dis 13 2 (2000) 113-120
    • (2000) Curr Opin Infect Dis , vol.13 , Issue.2 , pp. 113-120
    • Turnbull, P.C.1
  • 7
    • 0021205725 scopus 로고
    • Anthrax: the disease in relation to vaccines
    • Hambleton P., Carman J.A., and Melling J. Anthrax: the disease in relation to vaccines. Vaccine 2 2 (1984) 125-132
    • (1984) Vaccine , vol.2 , Issue.2 , pp. 125-132
    • Hambleton, P.1    Carman, J.A.2    Melling, J.3
  • 8
    • 0035852337 scopus 로고    scopus 로고
    • Anthrax vaccine: short-term safety experience in humans
    • Pittman P.R., Gibbs P.H., Cannon T.L., and Friedlander A.M. Anthrax vaccine: short-term safety experience in humans. Vaccine 20 5-6 (2001) 972-978
    • (2001) Vaccine , vol.20 , Issue.5-6 , pp. 972-978
    • Pittman, P.R.1    Gibbs, P.H.2    Cannon, T.L.3    Friedlander, A.M.4
  • 9
    • 0033549124 scopus 로고    scopus 로고
    • Anthrax as a biological weapon: medical and public health management. Working Group on Civilian Biodefense
    • Inglesby T.V., Henderson D.A., Bartlett J.G., Ascher M.S., Eitzen E., Friedlander A.M., et al. Anthrax as a biological weapon: medical and public health management. Working Group on Civilian Biodefense. JAMA 281 18 (1999) 1735-1745
    • (1999) JAMA , vol.281 , Issue.18 , pp. 1735-1745
    • Inglesby, T.V.1    Henderson, D.A.2    Bartlett, J.G.3    Ascher, M.S.4    Eitzen, E.5    Friedlander, A.M.6
  • 10
    • 0034724524 scopus 로고    scopus 로고
    • Surveillance for adverse events associated with anthrax vaccination-U.S. Department of Defense, 1998-2000. MMWR Morb Mortal Wkly Rep 2000;49(16):341-345.
    • Surveillance for adverse events associated with anthrax vaccination-U.S. Department of Defense, 1998-2000. MMWR Morb Mortal Wkly Rep 2000;49(16):341-345.
  • 11
    • 0037157268 scopus 로고    scopus 로고
    • Monitoring anthrax vaccine safety in US military service members on active duty: surveillance of 1998 hospitalizations in temporal association with anthrax immunization
    • Sato P.A., Reed R.J., Smith T.C., and Wang L. Monitoring anthrax vaccine safety in US military service members on active duty: surveillance of 1998 hospitalizations in temporal association with anthrax immunization. Vaccine 20 17-18 (2002) 2369-2374
    • (2002) Vaccine , vol.20 , Issue.17-18 , pp. 2369-2374
    • Sato, P.A.1    Reed, R.J.2    Smith, T.C.3    Wang, L.4
  • 13
    • 33748679345 scopus 로고    scopus 로고
    • Rabies virus glycoprotein as a carrier for anthrax protective antigen
    • Smith M.E., Koser M., Xiao S., Siler C., McGettigan J.P., Calkins C., et al. Rabies virus glycoprotein as a carrier for anthrax protective antigen. Virology 353 2 (2006) 344-356
    • (2006) Virology , vol.353 , Issue.2 , pp. 344-356
    • Smith, M.E.1    Koser, M.2    Xiao, S.3    Siler, C.4    McGettigan, J.P.5    Calkins, C.6
  • 14
    • 22544455984 scopus 로고    scopus 로고
    • Chimeric influenza virus hemagglutinin proteins containing large domains of the Bacillus anthracis protective antigen: protein characterization, incorporation into infectious influenza viruses, and antigenicity
    • Li Z.N., Mueller S.N., Ye L., Bu Z., Yang C., Ahmed R., et al. Chimeric influenza virus hemagglutinin proteins containing large domains of the Bacillus anthracis protective antigen: protein characterization, incorporation into infectious influenza viruses, and antigenicity. J Virol 79 15 (2005) 10003-10012
    • (2005) J Virol , vol.79 , Issue.15 , pp. 10003-10012
    • Li, Z.N.1    Mueller, S.N.2    Ye, L.3    Bu, Z.4    Yang, C.5    Ahmed, R.6
  • 15
    • 0025829008 scopus 로고
    • Protection against anthrax with recombinant virus-expressed protective antigen in experimental animals
    • Iacono-Connors L.C., Welkos S.L., Ivins B.E., and Dalrymple J.M. Protection against anthrax with recombinant virus-expressed protective antigen in experimental animals. Infect Immun 59 6 (1991) 1961-1965
    • (1991) Infect Immun , vol.59 , Issue.6 , pp. 1961-1965
    • Iacono-Connors, L.C.1    Welkos, S.L.2    Ivins, B.E.3    Dalrymple, J.M.4
  • 16
    • 0344442277 scopus 로고    scopus 로고
    • Protective immunity evoked against anthrax lethal toxin after a single intramuscular administration of an adenovirus-based vaccine encoding humanized protective antigen
    • Tan Y., Hackett N.R., Boyer J.L., and Crystal R.G. Protective immunity evoked against anthrax lethal toxin after a single intramuscular administration of an adenovirus-based vaccine encoding humanized protective antigen. Hum Gene Ther 14 17 (2003) 1673-1682
    • (2003) Hum Gene Ther , vol.14 , Issue.17 , pp. 1673-1682
    • Tan, Y.1    Hackett, N.R.2    Boyer, J.L.3    Crystal, R.G.4
  • 17
    • 0037369798 scopus 로고    scopus 로고
    • Venezuelan equine encephalitis virus-vectored vaccines protect mice against anthrax spore challenge
    • Lee J.S., Hadjipanayis A.G., and Welkos S.L. Venezuelan equine encephalitis virus-vectored vaccines protect mice against anthrax spore challenge. Infect Immun 71 3 (2003) 1491-1496
    • (2003) Infect Immun , vol.71 , Issue.3 , pp. 1491-1496
    • Lee, J.S.1    Hadjipanayis, A.G.2    Welkos, S.L.3
  • 18
    • 9244246299 scopus 로고    scopus 로고
    • Adaptation of the endogenous Salmonella enterica serovar Typhi clyA-encoded hemolysin for antigen export enhances the immunogenicity of anthrax protective antigen domain 4 expressed by the attenuated live-vector vaccine strain CVD 908-htrA
    • Galen J.E., Zhao L., Chinchilla M., Wang J.Y., Pasetti M.F., Green J., et al. Adaptation of the endogenous Salmonella enterica serovar Typhi clyA-encoded hemolysin for antigen export enhances the immunogenicity of anthrax protective antigen domain 4 expressed by the attenuated live-vector vaccine strain CVD 908-htrA. Infect Immun 72 12 (2004) 7096-7106
    • (2004) Infect Immun , vol.72 , Issue.12 , pp. 7096-7106
    • Galen, J.E.1    Zhao, L.2    Chinchilla, M.3    Wang, J.Y.4    Pasetti, M.F.5    Green, J.6
  • 19
    • 20444394421 scopus 로고    scopus 로고
    • Molecular basis for improved anthrax vaccines
    • Brey R.N. Molecular basis for improved anthrax vaccines. Adv Drug Deliv Rev 57 9 (2005) 1266-1292
    • (2005) Adv Drug Deliv Rev , vol.57 , Issue.9 , pp. 1266-1292
    • Brey, R.N.1
  • 20
  • 21
    • 0036176299 scopus 로고    scopus 로고
    • A recombinant carboxy-terminal domain of the protective antigen of Bacillus anthracis protects mice against anthrax infection
    • Flick-Smith H.C., Walker N.J., Gibson P., Bullifent H., Hayward S., Miller J., et al. A recombinant carboxy-terminal domain of the protective antigen of Bacillus anthracis protects mice against anthrax infection. Infect Immun 70 3 (2002) 1653-1656
    • (2002) Infect Immun , vol.70 , Issue.3 , pp. 1653-1656
    • Flick-Smith, H.C.1    Walker, N.J.2    Gibson, P.3    Bullifent, H.4    Hayward, S.5    Miller, J.6
  • 22
    • 12744269883 scopus 로고    scopus 로고
    • Passive immunotherapy for anthrax toxin mediated by an adenovirus expressing an anti-protective antigen single-chain antibody
    • Kasuya K., Boyer J.L., Tan Y., Alipui D.O., Hackett N.R., and Crystal R.G. Passive immunotherapy for anthrax toxin mediated by an adenovirus expressing an anti-protective antigen single-chain antibody. Mol Ther 11 2 (2005) 237-244
    • (2005) Mol Ther , vol.11 , Issue.2 , pp. 237-244
    • Kasuya, K.1    Boyer, J.L.2    Tan, Y.3    Alipui, D.O.4    Hackett, N.R.5    Crystal, R.G.6
  • 23
    • 0035984720 scopus 로고    scopus 로고
    • Protection against anthrax toxin by recombinant antibody fragments correlates with antigen affinity
    • Maynard J.A., Maassen C.B., Leppla S.H., Brasky K., Patterson J.L., Iverson B.L., et al. Protection against anthrax toxin by recombinant antibody fragments correlates with antigen affinity. Nat Biotechnol 20 6 (2002) 597-601
    • (2002) Nat Biotechnol , vol.20 , Issue.6 , pp. 597-601
    • Maynard, J.A.1    Maassen, C.B.2    Leppla, S.H.3    Brasky, K.4    Patterson, J.L.5    Iverson, B.L.6
  • 25
    • 7044222907 scopus 로고    scopus 로고
    • Functional analysis of Bacillus anthracis protective antigen by using neutralizing monoclonal antibodies
    • Brossier F., Levy M., Landier A., Lafaye P., and Mock M. Functional analysis of Bacillus anthracis protective antigen by using neutralizing monoclonal antibodies. Infect Immun 72 11 (2004) 6313-6317
    • (2004) Infect Immun , vol.72 , Issue.11 , pp. 6313-6317
    • Brossier, F.1    Levy, M.2    Landier, A.3    Lafaye, P.4    Mock, M.5
  • 26
    • 33745625378 scopus 로고    scopus 로고
    • A monoclonal antibody to Bacillus anthracis protective antigen defines a neutralizing epitope in domain 1
    • Rivera J., Nakouzi A., Abboud N., Revskaya E., Goldman D., Collier R.J., et al. A monoclonal antibody to Bacillus anthracis protective antigen defines a neutralizing epitope in domain 1. Infect Immun 74 7 (2006) 4149-4156
    • (2006) Infect Immun , vol.74 , Issue.7 , pp. 4149-4156
    • Rivera, J.1    Nakouzi, A.2    Abboud, N.3    Revskaya, E.4    Goldman, D.5    Collier, R.J.6
  • 27
    • 33745845204 scopus 로고    scopus 로고
    • Production and characterization of neutralizing monoclonal antibodies that recognize an epitope in domain 2 of Bacillus anthracis protective antigen
    • Gubbins M.J., Berry J.D., Corbett C.R., Mogridge J., Yuan X.Y., Schmidt L., et al. Production and characterization of neutralizing monoclonal antibodies that recognize an epitope in domain 2 of Bacillus anthracis protective antigen. FEMS Immunol Med Microbiol 47 3 (2006) 436-443
    • (2006) FEMS Immunol Med Microbiol , vol.47 , Issue.3 , pp. 436-443
    • Gubbins, M.J.1    Berry, J.D.2    Corbett, C.R.3    Mogridge, J.4    Yuan, X.Y.5    Schmidt, L.6
  • 29
    • 0031606401 scopus 로고    scopus 로고
    • Core particles of hepatitis B virus as carrier for foreign epitopes
    • Ulrich R., Nassal M., Meisel H., and Kruger D.H. Core particles of hepatitis B virus as carrier for foreign epitopes. Adv Virus Res 50 (1998) 141-182
    • (1998) Adv Virus Res , vol.50 , pp. 141-182
    • Ulrich, R.1    Nassal, M.2    Meisel, H.3    Kruger, D.H.4
  • 30
    • 0022996325 scopus 로고
    • The nucleocapsid of hepatitis B virus is both a T-cell-independent and a T-cell-dependent antigen
    • Milich D.R., and McLachlan A. The nucleocapsid of hepatitis B virus is both a T-cell-independent and a T-cell-dependent antigen. Science 234 4782 (1986) 1398-1401
    • (1986) Science , vol.234 , Issue.4782 , pp. 1398-1401
    • Milich, D.R.1    McLachlan, A.2
  • 31
    • 0023546339 scopus 로고
    • Improved immunogenicity of a peptide epitope after fusion to hepatitis B core protein
    • Clarke B.E., Newton S.E., Carroll A.R., Francis M.J., Appleyard G., Syred A.D., et al. Improved immunogenicity of a peptide epitope after fusion to hepatitis B core protein. Nature 330 6146 (1987) 381-384
    • (1987) Nature , vol.330 , Issue.6146 , pp. 381-384
    • Clarke, B.E.1    Newton, S.E.2    Carroll, A.R.3    Francis, M.J.4    Appleyard, G.5    Syred, A.D.6
  • 32
    • 0025316017 scopus 로고
    • B virus nucleocapsid assembly: primary structure requirements in the core protein
    • Birnbaum F., Nassal M., and Hepatitis. B virus nucleocapsid assembly: primary structure requirements in the core protein. J Virol 64 7 (1990) 3319-3330
    • (1990) J Virol , vol.64 , Issue.7 , pp. 3319-3330
    • Birnbaum, F.1    Nassal, M.2    Hepatitis3
  • 33
    • 0029950758 scopus 로고    scopus 로고
    • Dimorphism of hepatitis B virus capsids is strongly influenced by the C-terminus of the capsid protein
    • Zlotnick A., Cheng N., Conway J.F., Booy F.P., Steven A.C., Stahl S.J., et al. Dimorphism of hepatitis B virus capsids is strongly influenced by the C-terminus of the capsid protein. Biochemistry 35 23 (1996) 7412-7421
    • (1996) Biochemistry , vol.35 , Issue.23 , pp. 7412-7421
    • Zlotnick, A.1    Cheng, N.2    Conway, J.F.3    Booy, F.P.4    Steven, A.C.5    Stahl, S.J.6
  • 34
    • 0028832273 scopus 로고
    • Hepatitis B virus core particles as epitope carriers
    • Pumpens P., Borisova G.P., Crowther R.A., and Grens E. Hepatitis B virus core particles as epitope carriers. Intervirology 38 1-2 (1995) 63-74
    • (1995) Intervirology , vol.38 , Issue.1-2 , pp. 63-74
    • Pumpens, P.1    Borisova, G.P.2    Crowther, R.A.3    Grens, E.4
  • 35
    • 53649094508 scopus 로고    scopus 로고
    • Schodel F, Will H, Milich D. Hybrid hepatitis B virus core/pre-S particles expressed in live attenuated Salmonella for oral immunization. In: Chanock RM, Ginsberg HS, Brown F, Lerner RA, editors. Vaccines. New York: Cold Spring Harbor Laboratory Press; 1991. p. 319-25.
    • Schodel F, Will H, Milich D. Hybrid hepatitis B virus core/pre-S particles expressed in live attenuated Salmonella for oral immunization. In: Chanock RM, Ginsberg HS, Brown F, Lerner RA, editors. Vaccines. New York: Cold Spring Harbor Laboratory Press; 1991. p. 319-25.
  • 36
    • 32344446588 scopus 로고    scopus 로고
    • Expression, purification and characterization of the recombinant anthrax protective antigen
    • Xu J., Dong D., Song X., Ge M., Li G., Fu L., et al. Expression, purification and characterization of the recombinant anthrax protective antigen. Chin J Biotechnol 20 (2004) 652-655
    • (2004) Chin J Biotechnol , vol.20 , pp. 652-655
    • Xu, J.1    Dong, D.2    Song, X.3    Ge, M.4    Li, G.5    Fu, L.6
  • 37
    • 32344440772 scopus 로고    scopus 로고
    • Expression and characterization of the recombinant anthrax lethal factor
    • Guo Q., Xu J., Dong D., Fu L., and Chen W. Expression and characterization of the recombinant anthrax lethal factor. Acta Microbiol Sinica 44 (2004) 749-751
    • (2004) Acta Microbiol Sinica , vol.44 , pp. 749-751
    • Guo, Q.1    Xu, J.2    Dong, D.3    Fu, L.4    Chen, W.5
  • 38
    • 0344199395 scopus 로고    scopus 로고
    • New chimaeric hepatitis B virus core particles carrying hantavirus (serotype Puumala) epitopes: immunogenicity and protection against virus challenge
    • Ulrich R., Koletzki D., Lachmann S., Lundkvist A., Zankl A., Kazaks A., et al. New chimaeric hepatitis B virus core particles carrying hantavirus (serotype Puumala) epitopes: immunogenicity and protection against virus challenge. J Biotechnol 73 2-3 (1999) 141-153
    • (1999) J Biotechnol , vol.73 , Issue.2-3 , pp. 141-153
    • Ulrich, R.1    Koletzki, D.2    Lachmann, S.3    Lundkvist, A.4    Zankl, A.5    Kazaks, A.6
  • 39
    • 0033514992 scopus 로고    scopus 로고
    • Native display of complete foreign protein domains on the surface of hepatitis B virus capsids
    • Kratz P.A., Bottcher B., and Nassal M. Native display of complete foreign protein domains on the surface of hepatitis B virus capsids. Proc Natl Acad Sci USA 96 5 (1999) 1915-1920
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.5 , pp. 1915-1920
    • Kratz, P.A.1    Bottcher, B.2    Nassal, M.3
  • 40
    • 33646128931 scopus 로고    scopus 로고
    • Recombinant virus-like particles as a carrier of B- and T-cell epitopes of hepatitis C virus (HCV)
    • Mihailova M., Boos M., Petrovskis I., Ose V., Skrastina D., Fiedler M., et al. Recombinant virus-like particles as a carrier of B- and T-cell epitopes of hepatitis C virus (HCV). Vaccine 24 20 (2006) 4369-4377
    • (2006) Vaccine , vol.24 , Issue.20 , pp. 4369-4377
    • Mihailova, M.1    Boos, M.2    Petrovskis, I.3    Ose, V.4    Skrastina, D.5    Fiedler, M.6
  • 41
    • 2542463976 scopus 로고    scopus 로고
    • An amino-terminal segment of hantavirus nucleocapsid protein presented on hepatitis B virus core particles induces a strong and highly cross-reactive antibody response in mice
    • Geldmacher A., Skrastina D., Petrovskis I., Borisova G., Berriman J.A., Roseman A.M., et al. An amino-terminal segment of hantavirus nucleocapsid protein presented on hepatitis B virus core particles induces a strong and highly cross-reactive antibody response in mice. Virology 323 1 (2004) 108-119
    • (2004) Virology , vol.323 , Issue.1 , pp. 108-119
    • Geldmacher, A.1    Skrastina, D.2    Petrovskis, I.3    Borisova, G.4    Berriman, J.A.5    Roseman, A.M.6
  • 42
    • 0028061210 scopus 로고
    • Efficacy of a standard human anthrax vaccine against Bacillus anthracis spore challenge in guinea-pigs
    • Ivins B.E., Fellows P.F., and Nelson G.O. Efficacy of a standard human anthrax vaccine against Bacillus anthracis spore challenge in guinea-pigs. Vaccine 12 10 (1994) 872-874
    • (1994) Vaccine , vol.12 , Issue.10 , pp. 872-874
    • Ivins, B.E.1    Fellows, P.F.2    Nelson, G.O.3
  • 43
    • 0022655565 scopus 로고
    • Comparative efficacy of Bacillus anthracis live spore vaccine and protective antigen vaccine against anthrax in the guinea pig
    • Little S.F., and Knudson G.B. Comparative efficacy of Bacillus anthracis live spore vaccine and protective antigen vaccine against anthrax in the guinea pig. Infect Immun 52 2 (1986) 509-512
    • (1986) Infect Immun , vol.52 , Issue.2 , pp. 509-512
    • Little, S.F.1    Knudson, G.B.2
  • 44
    • 0035972045 scopus 로고    scopus 로고
    • Efficacy of a human anthrax vaccine in guinea pigs, rabbits, and rhesus macaques against challenge by Bacillus anthracis isolates of diverse geographical origin
    • Fellows P.F., Linscott M.K., Ivins B.E., Pitt M.L., Rossi C.A., Gibbs P.H., et al. Efficacy of a human anthrax vaccine in guinea pigs, rabbits, and rhesus macaques against challenge by Bacillus anthracis isolates of diverse geographical origin. Vaccine 19 23-24 (2001) 3241-3247
    • (2001) Vaccine , vol.19 , Issue.23-24 , pp. 3241-3247
    • Fellows, P.F.1    Linscott, M.K.2    Ivins, B.E.3    Pitt, M.L.4    Rossi, C.A.5    Gibbs, P.H.6
  • 45
    • 0035055295 scopus 로고    scopus 로고
    • Search for correlates of protective immunity conferred by anthrax vaccine
    • Reuveny S., White M.D., Adar Y.Y., Kafri Y., Altboum Z., Gozes Y., et al. Search for correlates of protective immunity conferred by anthrax vaccine. Infect Immun 69 5 (2001) 2888-2893
    • (2001) Infect Immun , vol.69 , Issue.5 , pp. 2888-2893
    • Reuveny, S.1    White, M.D.2    Adar, Y.Y.3    Kafri, Y.4    Altboum, Z.5    Gozes, Y.6
  • 46
    • 0034889864 scopus 로고    scopus 로고
    • HBV core particles as a carrier for B cell/T cell epitopes
    • Pumpens P., and Grens E. HBV core particles as a carrier for B cell/T cell epitopes. Intervirology 44 2-3 (2001) 98-114
    • (2001) Intervirology , vol.44 , Issue.2-3 , pp. 98-114
    • Pumpens, P.1    Grens, E.2
  • 48
    • 0032928864 scopus 로고    scopus 로고
    • Hepatitis B core particles as a universal display model: a structure-function basis for development
    • Pumpens P., and Grens E. Hepatitis B core particles as a universal display model: a structure-function basis for development. FEBS Lett 442 1 (1999) 1-6
    • (1999) FEBS Lett , vol.442 , Issue.1 , pp. 1-6
    • Pumpens, P.1    Grens, E.2
  • 49
    • 0026795429 scopus 로고
    • RNA- and DNA-binding activities in hepatitis B virus capsid protein: a model for their roles in viral replication
    • Hatton T., Zhou S., and Standring D.N. RNA- and DNA-binding activities in hepatitis B virus capsid protein: a model for their roles in viral replication. J Virol 66 9 (1992) 5232-5241
    • (1992) J Virol , vol.66 , Issue.9 , pp. 5232-5241
    • Hatton, T.1    Zhou, S.2    Standring, D.N.3
  • 51
    • 34547613366 scopus 로고    scopus 로고
    • Mucosal immunization with a novel nanoemulsion-based recombinant anthrax protective antigen vaccine protects against Bacillus anthracis spore challenge
    • Bielinska A.U., Janczak K.W., Landers J.J., Makidon P., Sower L.E., Peterson J.W., et al. Mucosal immunization with a novel nanoemulsion-based recombinant anthrax protective antigen vaccine protects against Bacillus anthracis spore challenge. Infect Immun 75 8 (2007) 4020-4029
    • (2007) Infect Immun , vol.75 , Issue.8 , pp. 4020-4029
    • Bielinska, A.U.1    Janczak, K.W.2    Landers, J.J.3    Makidon, P.4    Sower, L.E.5    Peterson, J.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.