Enhanced cell death and learning deficits after a mini-stroke in aged hippocampus

Neurobiology of Aging

Volumn 29, Issue 12, 2008, Pages 1847-1858

  Driscoll, Ira ^a   Hong, Nancy S ^a   Craig, Laura A ^a   Sutherland, Robert J ^a   McDonald, Robert J ^a  

^a UNIVERSITY OF LETHBRIDGE   (Canada)

Author keywords

Aging; Alzheimer's disease; Dementia; Learning and memory; Spatial memory; Stroke

Indexed keywords

ENDOTHELIN 1;

AGE DISTRIBUTION; AGED; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSOCIATION; BRAIN SIZE; CONTROLLED STUDY; DISEASE PREDISPOSITION; EXPERIMENTAL MODEL; HIPPOCAMPUS; LEARNING DISORDER; LEARNING TEST; MALE; MULTIINFARCT DEMENTIA; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; STROKE; TASK PERFORMANCE;

AGING; ANIMALS; APOPTOSIS; HIPPOCAMPUS; HUMANS; LEARNING DISORDERS; MALE; RATS; STROKE;

EID: 53649089109     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2007.04.025     Document Type: Article

References (32)

1. Ball M.J., Fisman M., Hachinski V., Blume W., Fox A., Kral V.A., Kirshen A.J., Fox H., and Merskey H. A new definition of Alzheimer's disease: a hippocampal dementia. Lancet 1 (1985) 14-16
2. Barba R. Poststroke dementia: clinical features and risk factors. Stroke 31 (2003) 1494-1501
3. Biernaskie J., Corbett D., Peeling J., Wells J., and Lei H. A serial MR study of cerebral blood flow changes and lesion development following endothelin-1-induced ischemia in rats. Magn. Reson. Med. 46 (2001) 827-830
4. Bizon J.L., and Gallagher M. Production of new cells in the rat dentate gyrus over the lifespan: relation to cognitive decline. Eur. J. Neurosci. 18 (2003) 215-219
5. Corder E.H., Saunders A.M., Strittmatter W.J., Schmechel D.E., Gaskell P.C., Small G.W., Roses A.D., Haines J.L., and Pericak-Vance M.A. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261 (1993) 921-923
6. Driscoll I., Howard S.R., Stone J.C., Monfils M.H., Tomanek B., Brooks W.M., and Sutherland R.J. The aging hippocampus: a multilevel analysis in the rat. Neuroscience 139 (2006) 1173-1185
7. Duckworth E.A., Butler T.L., De Mesquita D., Collier S.N., Collier L., and Pennypacker K.R. Temporary focal ischemia in the mouse: technical aspects and patterns of Fluoro-Jade evident neurodegeneration. Brain Res. 1042 (2005) 29-36
8. Esiri M.M. Which vascular lesions are of importance in vascular dementia?. Ann. NY Acad. Sci. 903 (2000) 239-243
9. Ferbinteanu J., and McDonald R.J. Dorsal and ventral hippocampus-same or different?. Psychobiology 28 (2000) 314-324
10. Gorelick P.B. Risk factors for vascular dementia and Alzheimer's disease. Stroke 35 (2004) 2620-2622
11. Hachinski V. Vascular dementia: a radical redefinition. Dementia 5 (1994) 130-132
12. Hachinski V., and Munoz D. Vascular factors in cognitive impairment: where are we now?. Ann. NY Acad. Sci. 903 (2007) 1-5
13. Haring H. Cognitive impairment after stroke. Curr. Opin. Neurol. 15 (2002) 79-84
14. Heyman A., Fillenbaum G.G., Welsh-Bohmer K.A., Gearing M., Mirra S.S., Mohs R.C., Peterson B.L., and Pieper C.F. Cerebral infarcts in patients with autopsy-proven Alzheimer's disease: CERAD. Part XVIII. Consortium to establish a registry for Alzheimer's disease. Neurology 51 (1998) 159-162
15. McDonald R.J. Multiple combinations of co-factors produce variants of age-related cognitive decline: a theory. Can. J. Exp. Psychol. 56 (2002) 221-339
16. McDonald R.J., and Hong N.S. Rats with hippocampal damage are impaired on place learning in the water task even when overtrained under constrained behavioral conditions. Hippocampus 10 (2000) 153-161
17. McDonald R.J., Hong N.S., Craig L.A., Holahan M.L., and Muller R.U. NMDA receptor blockade by CPP impairs post-training consolidation of a rapidly acquired spatial representation in rat hippocampus. Eur. J. Neurosci. 22 (2005) 1201-1213
18. McDonald R.J., and White N.M. Parallel information processing in the water maze: evidence for independent memory systems involving dorsal striatum and hippocampus. Behav. Neural Biol. 61 (1994) 260-270
19. Morris R.G.M. Spatial localization does not require the presence of local cues. Learn. Motiv. 12 (1981) 239-260
20. O'Brien J.T., Erkinjuntti T., Reisberg B., Roman G., Sawada T., Pantoni L., Bowler J.V., Ballard C., DeCarli C., Gorelick P.B., Rockwood K., Burns A., Gauthier S., and DeKosky S.T. Vascular cognitive impairment. Lancet Neurol. 2 (2003) 89-98
21. Olicheney J.M., Hansen L.A., Lee J.H., Hofstetter C.R., Katzman R., and Thal L.J. Relationship between severe amyloid angiopathy, apolipoprotein E genotype, and vascular lesions in Alzheimer's disease. Ann. NY Acad. Sci. 903 (2000) 138-143
22. Robinson R.G., Starr L.B., Lipsey J.R., Rao K., and Price T.R. A two-year longitudinal study of post-stroke mood disorders: dynamic changes associated variables over the first six months of follow-up. Stroke 15 (1984) 510-517
23. Schacter D.L., and Tulving E. Memory Systems (1994), MIT Press, Cambridge, MA
24. Schmued L.C., and Hopkins K.J. Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration. Brain Res. 874 (2000) 123-130
25. Schneider J.A., Wilson R.S., Bienias J.L., Evans D.A., and Bennett D.A. Cerebral infarctions and the likelihood of dementia from Alzheimer disease pathology. Neurology 62 (2004) 1148-1155
26. Shetty A.K., Hattiangady B., and Shetty G.A. Stem/progenitor cell proliferation factors FGF-2, IGF-2, and VEGF exhibit early decline during the course of aging in the hippocampus: role of astrocytes. Glia 51 (2005) 173-186
27. Shi J., Yang S.H., Stubley L., Day A.L., and Simpkins J.W. Hypoperfusion induces overexpression of a β-amyloid precursor protein mRNA in a focal ischemic rodent model. Brain Res. 853 (2000) 1-4
28. Shipley R.D., and Muller-Delp J.M. Aging decreases vasoconstrictor responses of coronary resistance arterioles through endothelium-dependent mechanisms. Cardiovasc. Res. 66 (2005) 374-383
29. Sigurdsson E.M., Lee J.M., Dong X.W., Hejna M.J., and Lorens S.A. Bilateral injections of amyloid-β 25-35 into the amygdala of young Fisher rats: behavioral, neurochenical, and time dependent histopathological effects. Neurobiol. Aging 18 (1997) 591-608
30. Synder J.S., Hong N.S., McDonald R.J., and Wojtowicz J.M. An essential role for adult neurogenesis in long-term memory. Neuroscience 130 (2005) 843-852
31. Sutherland R.J., McDonald R.J., and Savage D.D. Prenatal exposure to moderate levels of ethanol can have long-lasting effects on learning and memory in adult offspring. Psychobiology 28 (2000) 532-539
32. Sutherland R.J., and Rudy J.W. Place learning in the Morris place navigation task is impaired by damage to the hippocampal formation even if the temporal demands are reduced. Psychobiology 16 (1988) 157-163