Suppression and recovery of the hypothalamic function after high-dose corticosteroid treatment in preterm infants

Neonatology

Volumn 94, Issue 3, 2008, Pages 170-175

  Ng, P C ^a   Lam, C W K ^a   Lee, C H ^a   Chan, I H S ^a   Wong, S P S ^a   Fok, T F ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Corticosteroids; Corticotropin releasing hormone; Hypothalamus

Indexed keywords

CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; DEXAMETHASONE; HYDROCORTISONE;

ADRENAL FUNCTION; ARTICLE; CLINICAL ARTICLE; CONVALESCENCE; CORTICOTROPIN BLOOD LEVEL; DRUG DOSE REDUCTION; DRUG MEGADOSE; DRUG WITHDRAWAL; FEMALE; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYPOPHYSIS FUNCTION; HYPOTHALAMUS FUNCTION; MALE; PREMATURITY; PRIORITY JOURNAL; VERY LOW BIRTH WEIGHT;

ADRENOCORTICOTROPIC HORMONE; BRONCHOPULMONARY DYSPLASIA; CORTICOTROPIN-RELEASING HORMONE; DEXAMETHASONE; FEMALE; GLUCOCORTICOIDS; HUMANS; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, VERY LOW BIRTH WEIGHT; LEAST-SQUARES ANALYSIS; LONGITUDINAL STUDIES; MALE; PITUITARY-ADRENAL SYSTEM; PROSPECTIVE STUDIES; VENTILATOR WEANING;

EID: 53549132510     PISSN: 16617800     EISSN: 16617819     Source Type: Journal    
DOI: 10.1159/000143396     Document Type: Article

References (20)

1. Halliday HL, Ehrenkranz RA, Doyle LW: Moderately early (7-14 days) postnatal corticosteroids for preventing chronic lung disease in preterm infants. Cochrane Database Syst Rev 2003;1:CD001144.
2. Stark AR, Carlo WA, Tyson JE, Papile LA, Wright LL, Shankaran S, Donovan EF, Oh W, Bauer CR, Saha S, Poole WK, Stoll AJ: National Institute of Child Health and Human Development Neonatal Research Network. Adverse effects of early dexamethasone treatment in extremely low birth weight infants. N Engl J Med 2001;344:95-101.
3. Ng PC: The effectiveness and side effects of dexamethasone in preterm infants with bronchopulmonary dysplasia. Arch Dis Child 1993;68:330-336.
4. Ng PC, Wong GWK, Lam CWK, Lee CH, Fok TF, Wong MY, Wong W, Chan DC: Pituitary-adrenal suppression and recovery in preterm very low birth weight infants after dexamethasone treatment for bronchopulmonary dysplasia. J Clin Endocrinol Metab 1997;82:2429-2432.
5. Ng PC, Blackburn ME, Brownlee KG, Buckler JMH, Dear PRF: Adrenal response in very low birth weight babies after dexamethasone treatment for bronchopulmonary dysplasia. Arch Dis Child 1989;64:1721-1726.
6. Ford LR, Willi SM, Hollis BW, Wright NM: Suppression and recovery of the neonatal hypothalamic-pituitary-adrenal axis after prolonged dexamethasone therapy. J Pediatr 1997;131:722-726.
7. Ng PC, Brownlee KG, Dear PRF: Gastroduodenal perforation in preterm babies treated with dexamethasone for bronchopulmonary dysplasia. Arch Dis Child 1991;66:1164-1166.
8. Hanna CE, Keith LD, Colasurdo MA, Buffkin DC, Laird MR, Mandel SH, Cook DM, LaFranchi SH, Reynolds JW: Hypothalamic pituitary adrenal function in the extremely low birth weight infant. J Clin Endocrinol Metab 1993;76:384-387.
9. Hashimoto K, Nishioka T, Numata Y, Ogasa T, Kageyama J, Suemaru S: Plasma levels of corticotropin-releasing hormone in hypothalamic-pituitary-adrenal disorders and chronic renal failure. Acta Endocrinol 1993;128:503-507.
10. Torricelli M, Ignacchiti E, Giovannelli A, Merola A, Scarpetti E, Calonaci G, Picciolini E, Florio P, Reis FM, Linton EA, Petraglia F: Maternal plasma corticotrophin-releasing factor and urocortin levels in post-term pregnancies. Eur J Endocrinol 2006;154:281-285.
11. Goldstein H: Multilevel statistical models; in Kendall's Library of Statistics 3. London, Edward Arnold, 1995, pp 87-94.
12. Goland RS, Wardlow SL, Stark RI, Brown LS Jr, Frantz AG: High levels of corticotropin-releasing hormone immunoactivity in maternal and fetal plasma during pregnancy. J Clin Endocrinol Metab 1986;63:1199-1203.
13. Majzoub JA, McGregor JA, Lockwood CJ, Smith R, Taggart MS, Schulkin J: A central theory of preterm and term labor: putative role for corticotropin- releasing hormone. Am J Obstet Gynecol 1999;180:232S-241S.
14. Tropper PJ, Goland RS, Wardlaw SL, Fox HE, Frantz AG: Effects of betamethasone on maternal plasma corticotropin-releasing factor, ACTH, and cortisol during pregnancy. J Perinatol 1987;15:221-225.
15. Marinoni E, Korebrits C, Iorio R, Cosmi EV, Challis JR: Effect of betamethasone in vivo on placental corticotropin-releasing hormone in human pregnancy. Am J Obstet Gynecol 1998;178:770-778.
16. Brigell DF, Fang VS, Rosenfield RL: Recovery of responses of ovine corticotropin-releasing hormone after withdrawal of a short course of glucocorticoid. J Clin Endocrinol Metab 1992;74:1036-1039.
17. Gomez MT, Magiakou MA, Mastorakos G, Chrousos GP: The pituitary corticotroph is not the rate limiting step in the postoperative recovery of the hypothalamic-pituitary-adrenal axis in patients with Cushing syndrome. J Clin Endocrinol Metab 1993;77:173-177.
18. Graber AL, Ney RL, Nicholson WE, Island DP, Liddle GW: Natural history of pituitary-adrenal recovery following long-term suppression with corticosteroids. J Clin Endocrinol Metab 1965;25:11-16.
19. Muglia LJ, Jacobson L, Luedke C, Vogt SK, Schaefer ML, Dikkes P, Fududa S, Sakai Y, Suda T, Majzoub JA: Corticotropin-releasing hormone links pituitary adrenocorticotropin gene expression and release during adrenal insufficiency. J Clin Invest 2000;105:1269-1277.
20. Ng PC, Lam CWK, Lee CH, Fok TF, Chan IH, Ma KC, Wong E: Reference ranges and factors affecting the human corticotropin-releasing hormone test in preterm, very low birth weight infants. J Clin Endocrinol Metab 2002;87:4621-4628.