Effects of γ-irradiation, storage and hydration on osteoinductivity of DBM and DBM/AM composite

Journal of Biomedical Materials Research - Part A

Volumn 87, Issue 2, 2008, Pages 373-379

  Qiu, Qing Qing ^a   Connor, Jerome ^a  

^a LIFECELL CORPORATION   (United States)

Author keywords

irradiation; Animal model; Demineralized bone matrix; Osteoinductivity; Sterilization

Indexed keywords

BONE; CARBON FIBER REINFORCED PLASTICS; CURING; HYDRATES; HYDRATION; MATRIX ALGEBRA; METALLIC MATRIX COMPOSITES; POLYMETHYL METHACRYLATES; RADIATION;

ANIMAL MODEL; DEMINERALIZED BONE MATRIX; OSTEOINDUCTIVITY; STERILIZATION;

IRRADIATION;

ALKALINE PHOSPHATASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE CONDUCTION; BONE MATRIX; CONTROLLED STUDY; ENVIRONMENTAL TEMPERATURE; ENZYME ACTIVITY; GAMMA IRRADIATION; HISTOLOGY; HYDRATION; LOW TEMPERATURE; NONHUMAN; OSSIFICATION; RAT; STORAGE;

ALKALINE PHOSPHATASE; ANIMALS; BIOCOMPATIBLE MATERIALS; BONE DEMINERALIZATION TECHNIQUE; BONE MATRIX; BONE REGENERATION; BONE SUBSTITUTES; GAMMA RAYS; HUMANS; MATERIALS TESTING; OSTEOGENESIS; RATS; RATS, NUDE; TEMPERATURE; TISSUE PRESERVATION; WATER;

EID: 53549124413     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31790     Document Type: Article

References (21)

1. Urist MR. Bone formation by autoinduction. Science 1965;150:893-899.
2. Iwata H, Sakano S, Itoh T, Bauer TW. Demineralized bone matrix and native bone morphogenetic protein in orthopaedic surgery. Clin Orthop Relat Res 2002;395:99-109.
3. Glowacki J, Kaban LB, Murray JE, Folkman J, Mulliken JB. Application of the biological principle of induced osteogenesis for carnofacial defects. Lancet 1981;1:959-962.
4. Michelson JD, Curl LA. Use of demineralized bone matrix in hindfoot arthrodesis. Clin Orthop Relat Res 1996;325:203-208.
5. Tiedeman JJ, Huurman WW, Connolly JF, Strates BS. Healing of a large nonossifying fibroma after grafting with bone matrix and marrow. A case report. Clin Orthop Relat Res 1991;265:302-305.
6. Boden SD. Overview of the biology of lumbar spine fusion and principles for selecting a bone graft substitute. Spine 2002;27:S26-S31.
7. Han B, Yang Z, Nimni M. Effects of moisture and temperature on the osteoinductivity of demineralized bone matrix. J Orthop Res 2005;23:855-861.
8. Takikawa S, Bauer TW, Kambic H, Togawa D. Comparative evaluation of the osteoinductivity of two formulations of human demineralized bone matrix. J Biomed Mater Res A 2003;65:37-42.
9. Bomback DA, Grauer JN, Lugo R, Troiano N, Patel TC, Friedlaender GE. Comparison of posterolateral lumbar fusion rates of Grafton putty and OP-1 in an athymic rat model. Spine 2004;29:1612-1617.
10. Peterson B, Whang PG, Iglesias R, Wang JC, Lieberman JR. Osteoconductivity of commercially available demineralized bone matrix. J Bone Joint Surg Am A 2004;86:2243-2250.
11. Lee YP, Jo M, Luna M, Chien B, Lieberman JR, Wang JC. The efficacy of different commercially available demineralized bone matrix substances in an athymic rat model. J Spinal Discord Tech 2005;18:439-444.
12. Qiu QQ, Mendenhall HV, Garlick DS, Connor J. Evaluation of bone regeneration at critical-sized calvarial defect by DBM/AM composite. J Biomed Mater Res Part B: Appl Biomater 2007;81:516-523.
13. Qiu QQ, Shih MS, Stock K, Panzitta T, Murphy PA, Roesch SC, Connor J. Evaluation of DBM/AM composite as a graft substitute for posterolateral lumbar fusion. J Biomed Mater Res Part B: Appl Biomater 2007;82:239-245.
14. Stevenson SDVM. Autograft/allografts biology of bone grafts. Orthop Clin North Am 1999;30:543-545.
15. Stevenson S. The effect of processing and low dose irradiation on cortical bone grafts. Clin Ortho Relat Res 2000;375: 275-285.
16. Gertzman AA, Sunwoo MH, Raushi D, Dunn M. The effect of cold gamma radiation sterilisation on the properties of demineralized bone matrix. In: Kennedy JF, Phillips GO, Williams PA, editors. Sterilisation of Tissues Using Ionising Radiations. Boca Raton: CRC Press; 2005. p 151-156.
17. Hayzlett M, Griffey S, Greenleaf G. Rapid heat transfer dynamics and cold gamma sterilisation methods for soft tissue allografts. In: Kennedy JF, Phillips GO, Williams PA, editors. Sterilisation of Tissues Using Ionising Radiations. Boca Raton: CRC Press; 2005. p 117-122.
18. Hayzlett M, Honey MJ. Tissue irradiation system and apparatus. 2005. Patent No. WQ/2005/022555.
19. Griffey S, Schwarde ND, Wright CG. Particulate dermal matrix as an injectable soft tissue replacement material. J Biomed Mater Res 2001;58:10-15.
20. Kearney JN, Holland KT, Bojar R. Ethylene oxide sterilisation of bone alloimplants. Clin Mater 1993;12:129-135.
21. Aspenberg P, Lindqvist SB. Ethene oxide and bone induction. Controversy remains. Acta Orthop Scand 1998;69:173-176.