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In 1986 Ito et al. described a bifunctional gold catalyst that acts as both a classical Lewis acid and a Brønsted base, and thus is capable of catalyzing an asymmetric aldol reaction. This reaction does not involve a π-activation step: Y. Ito, M. Sawamura, T. Hayashi, J. Am. Chem. Soc. 1986, 108, 6405
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In 1986 Ito et al. described a bifunctional gold catalyst that acts as both a classical Lewis acid and a Brønsted base, and thus is capable of catalyzing an asymmetric aldol reaction. This reaction does not involve a π-activation step: Y. Ito, M. Sawamura, T. Hayashi, J. Am. Chem. Soc. 1986, 108, 6405.
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II complex has been structurally characterized: C. J. Burns, R. A. Andersen, J. Am. Chem. Soc. 1987, 109, 915.
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II complex has been structurally characterized: C. J. Burns, R. A. Andersen, J. Am. Chem. Soc. 1987, 109, 915.
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