TNF-α could be responsible for disulfiram-mediated hepatotoxicity

Journal of Hepatology

Volumn 49, Issue 5, 2008, Pages 865-866

  Cvek, Boris ^a  

^a PALACKÝ UNIVERSITY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOTRANSFERASE; BILIRUBIN; DISULFIRAM; DITHIOCARBAMIC ACID; FAS ASSOCIATED DEATH DOMAIN PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ALCOHOLISM; CYTOTOXICITY; DISEASE ASSOCIATION; HUMAN; LETTER; LIVER DISEASE; LIVER TOXICITY; PRIORITY JOURNAL;

ALCOHOL DETERRENTS; ANIMALS; DISULFIRAM; HUMANS; LIVER; MICE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 53549106615     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2008.07.001     Document Type: Letter

References (6)

1. Lu J.W., Wang H., Yan-Li J., Zhang C., Ning H., Li X.Y., et al. Differential effects of pyrrolidine dithiocarbamate on TNF-α-mediated liver injury in two different models of fulminant hepatitis. J Hepatol 48 (2008) 442-452
2. Bjornsson E., Nordlinder H., and Olsson R. Clinical characteristics and prognostic markers in disulfiram-induced liver injury. J Hepatol 44 (2006) 791-797
3. Bradham C.A., Plumpe J., Manns M.P., Brenner D.A., and Trautwein C. Mechanisms of hepatic toxicity. TNF-induced liver injury. Am J Physiol 275 (1998) G387-G392
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6. Cvek B., and Dvorak Z. Targeting of nuclear factor-κB and proteasome by dithiocarbamate complexes with metals. Curr Pharm Des 13 (2007) 3155-3167