Phase transformation of erythromycin a dihydrate during fluid bed drying

Journal of Pharmaceutical Sciences

Volumn 97, Issue 9, 2008, Pages 4020-4029

  Römer, Meike ^a   Heinämäki, Jyrki ^a   Miroshimyk, Inna ^a   Kivikero, Niina ^a   Sandler, Niklas ^b   Rantanen, Jukka ^c   Yliruusi, Jouko ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b ASTRAZENECA   (United Kingdom)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Dehydration; Drying; Erythromycin; In line near infrared spectroscopy; Miniaturized fluid bed; Phase transformation; Principal component analysis; X ray powder diffractometry

Indexed keywords

ERYTHROMYCIN; MICROCRYSTALLINE CELLULOSE;

ARTICLE; DRUG PELLET; DRUG TRANSFORMATION; FLUIDIZED BED; INFRARED SPECTROMETRY; MOISTURE; NEAR INFRARED SPECTROMETRY; PRINCIPAL COMPONENT ANALYSIS; SOLID STATE; X RAY POWDER DIFFRACTION;

EID: 53549103568     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21272     Document Type: Article

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