Effect and molecular mechanism of tashinon IIA on the hypertrophic cadiocyte due to abdominal aorta stenosis in rats

Chinese Pharmaceutical Journal

Volumn 43, Issue 17, 2008, Pages

  Li, Yong Sheng ^a   Wang, Zhao Hua ^a   Wang, Jin ^a   Yan, Li ^a   Yong, Yong Quan ^a   Liang, Qian Sheng ^a   Zheng, Zhi ^a   Yang, Guang Tian ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Angiotensin II receptor; Hypertrophic myocardium; Nitric oxide synthase; Pressure overload; Protein kinase C; Tanshinone IIA

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PROTEIN KINASE C; TANSHINONE; VALSARTAN;

ABDOMINAL AORTA; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA STENOSIS; ARTICLE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE MASS; HEART LEFT VENTRICLE VOLUME; NONHUMAN; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 53549084606     PISSN: 10012494     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. YASUNARI K, MAEDA K, NAKAMURA M, et al. Left ventricular hypertrophy and angiotensin II receptor blocking agents [J]. Curr Med Chem Cardiovasc Hematol Agents, 2005,3(1):61-67.
2. CHENG T H, SHIH N L, CHEN S Y, et al. Nitric oxide inhibits endothelin-1-induced cardiomyocyte hypertrophy through cGMP-mediated suppression of extracellular-signal regulated kinase phosphorylation [J]. Mol Pharmacol, 2005,68(4):1183-1192.
3. FU S G, XIE X J, JI L M, et al. Influence of nitric oxide on the angiotensin II-activated protein kinase C activity in cultured neonatal rat cardiomycytes [J]. Acta Physiol Sin, 2003,55(1):53-57.
4. WANG Z H, LIANG Q S, ZHENG Z. The effect of tanshinone on L-type calcium current in hypertrophic myocardium [J]. Chin J Hypertens, 2006,14(6):450-454.
5. ZHAN C Y, TAO X L, HAN S J, et al. Effects of tanshinone IIA on the cardiac content of aldosterone and the expression of CYP11B1 and CYP11B2 mRNA related to aldosterone synthesis in spontaneously hypertensive rats [J]. Chin Pharm J, 2005,40(1):31-33.
6. ROSE M, BALAKUMAR P, SINGH M, et al. Ameliorative effect of combination of fenofibrate and rosiglitazone in pressure overload-induced cardiac hypertrophy in rats [J]. Pharmacology, 2007,80(2-3):177-184.
7. KOSUGI R, SHIOI T, WATANABE MAEDA K, et al. Angiotensin II receptor antagonist attenuates expression of aging markers in diabetic mouse heart [J]. Circ Ulation, 2006,70(4):482-488.
8. JUAN EDUARDO CARREX O, FELIPE APABLAZA, MARíA PAZ OCARANZA, et al. Cardiac hypertrophy: molecular and cellular events [J]. Rev Esp Cardiol, 2006,59(5):473-486.
9. TAKEISHI Y, GOTO K, KUBOTA I. Role of diacylglycerol kinase in cellular regulatory processes: a new regulator for cardiomyocyte hypertrophy [J]. Pharmacol Ther, 2007,115(3):352-359.
10. OKAZAKI H, MINAMINO T, TSUKAMOTO O, et al. Angiotensin II type 1 receptor blocker prevents atrial structural remodeling in rats with hypertension induced by chronic nitric oxide inhibition [J]. Hypertens Res, 2006,29(4):277-284.
11. NAKASHIMA H, SUZUKI H, OHTSU H, et al. Angiotensin II regulates vascular and endothelial dysfunction: recent topics of Angiotensin II type-1 receptor signaling in the vasculature [J]. Curr Vasc Pharmacol, 2006,4(1):67-78.
12. 2+ level induced by angiotensin in cultured porcine aortic endothelial cells [J]. Chin J Hypert, 2006,14(11):882-885.