Design of potent aspartic protease inhibitors to treat various diseases

Archiv der Pharmazie

Volumn 341, Issue 9, 2008, Pages 523-535

  Nguyen, Jeffrey Tri ^a   Hamada, Yoshio ^a   Kimura, Tooru ^a   Kiso, Yoshiaki ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Beta secretase inhibitor; HIV Protease inhibitor; HTLV Protease inhibitor; Plasmepsin inhibitor; Renin inhibitor

Indexed keywords

AG 1776; ALLONORSTATINE; ALLOPHENYLNORSTATINE; ASPARTIC PROTEINASE INHIBITOR; BETA SECRETASE; BETA SECRETASE INHIBITOR; JE 1482; JE 2147; JE 533; KMI 008; KMI 370; KMI 429; KMI 574; KMI 684; KNI 10006; KNI 1966; KNI 227; KNI 577; KNI 727; KNI 764; KYNOSTATIN 272; NORSTATINE; PHENYLNORSTATINE; PHENYLTHIONORSTATINE; PLASMEPSIN I; PLASMEPSIN II; PLASMEPSIN INHIBITOR; PROTEINASE; PROTEINASE INHIBITOR; RENIN; RENIN INHIBITOR; RITONAVIR; SM 319777; UNCLASSIFIED DRUG;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; DRUG ABSORPTION; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN T CELL LEUKEMIA VIRUS 1; HYPERTENSION; MALARIA; NONHUMAN; PRIORITY JOURNAL; REVIEW; SPASTIC PARAPLEGIA; SPINAL CORD DISEASE; STRUCTURE ACTIVITY RELATION; T CELL LEUKEMIA; X RAY CRYSTALLOGRAPHY;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID; ASPARTIC ENDOPEPTIDASES; DRUG DESIGN; HIV PROTEASE INHIBITORS; HUMANS; PROTEASE INHIBITORS; RENIN;

EID: 53549084594     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200700267     Document Type: Review

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