Hyperplasia of hair follicles and other adnexal structures in cutaneous lymphoproliferative disorders: A study of 53 cases, including so-called pseudolymphomatous folliculitis and overt lymphomas

American Journal of Surgical Pathology

Volumn 32, Issue 10, 2008, Pages 1468-1478

  Kazakov, Dmitry V ^a   Belousova, Irena E ^b   Kacerovska, Denisa ^a   Sima, Radek ^a   Vanecek, Tomas ^a   Vazmitel, Marina ^c   Pizinger, Karel ^a   Michal, Michal ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b Medical Military Academy   (Russian Federation)

^c Institute of Postgradual Studies   (Belarus)

Author keywords

Adnexal tumors; Cutaneous lymphoma; Folliculotropism; Pseudolymphoma; Translocation

Indexed keywords

ANTIBIOTIC AGENT; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; T LYMPHOCYTE RECEPTOR;

ADULT; AGED; ARTICLE; B CELL LYMPHOMA; CD3+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; FEMALE; FOLLICULITIS; HAIR FOLLICLE; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN TISSUE; HYPERPLASIA; LARGE CELL LYMPHOMA; LYMPHOMA; MALE; MYCOSIS FUNGOIDES; PROTEIN EXPRESSION; PSEUDOLYMPHOMATOUS FOLLICULITIS; T CELL LYMPHOMA; COMPARATIVE STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION REGULATION; GENE REARRANGEMENT; GENE TRANSLOCATION; GENETICS; IMMUNOGLOBULIN HEAVY CHAIN GENE; IMMUNOHISTOCHEMISTRY; LYMPHOPROLIFERATIVE DISEASE; MIDDLE AGED; PATHOLOGY; PSEUDOLYMPHOMA; RETROSPECTIVE STUDY; SKIN DISEASE; SKIN TUMOR; TIME; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; FOLLICULITIS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REARRANGEMENT, T-LYMPHOCYTE; GENES, IMMUNOGLOBULIN HEAVY CHAIN; HAIR FOLLICLE; HUMANS; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; LYMPHOMA; LYMPHOPROLIFERATIVE DISORDERS; MALE; MIDDLE AGED; PSEUDOLYMPHOMA; RETROSPECTIVE STUDIES; SKIN DISEASES; SKIN NEOPLASMS; TIME FACTORS; TRANSLOCATION, GENETIC; TREATMENT OUTCOME;

EID: 53449102212     PISSN: 01475185     EISSN: 15320979     Source Type: Journal    
DOI: 10.1097/PAS.0b013e31817bdcfb     Document Type: Article

References (42)

1. Abenoza P, Ackerman AB. Neoplasms With Eccrine differentiation. 1st ed. Philadelphia, London: Lea & Febgier; 1990: 595 pages.
2. Arai E, Okubo H, Tsuchida T, et al. Pseudolymphomatous folliculitis: a clinicopathologic study of 15 cases of cutaneous pseudolymphoma with follicular invasion. Am J Surg Pathol. 1999; 23:1313-1319.
3. Arai E, Shimizu M, Hirose T. A review of 55 cases of cutaneous lymphoid hyperplasia: reassessment of the histopathologic findings leading to reclassification of 4 lesions as cutaneous marginal zone lymphoma and 19 as pseudolymphomatous folliculitis. Hum Pathol. 2005;36:505-511.
4. Bergman R, Khamaysi Z, Sahar D, et al. Cutaneous lymphoid hyperplasia presenting as a solitary facial nodule: clinical, histopathological, immunophenotypical, and molecular studies. Arch Dermatol. 2006;142:1561-1566.
5. Boudova L, Kazakov DV, Sima R, et al. Cutaneous lymphoid hyperplasia and other lymphoid infiltrates of the breast nipple: a retrospective clinicopathologic study of fifty-six patients. Am J Dermatopathol. 2005;27:375-386.
6. Burg G, Schmockel C. Syringolymphoid hyperplasia with alopecia - a syringotropic cutaneous T-cell lymphoma? Dermatology. 1992;184:306-307.
7. Burg G, Kempf W. Cutaneous Lymphomas. Boca Raton: Taylor and Francis Group; 2005: 556 pages.
8. Carrozza PM, Kempf W, Kazakov DV, et al. A case of Sezary's syndrome associated with granulomatous lesions, myelodysplastic syndrome and transformation into CD30-positive large-cell pleomorphic lymphoma. Br J Dermatol. 2002;147:582-586.
9. Cerroni L, Fink-Puches R, Back B, et al. Follicular mucinosis: a critical reappraisal of clinicopathologic features and association with mycosis fungoides and Sezary syndrome. Arch Dermatol. 2002; 138:182-189.
10. Cerroni L, Gatter K, Kerl H. An Illustrated Guide to Skin Lymphoma. 2nd ed. Oxford: Blackwell Publishing Ltd; 2004: 186 pages.
11. Dargent JL, Debois J, Sass U, et al. Unusual T cell pseudolymphoma with features of so-called pseudolymphomatous folliculitis. Dermatology. 2002;204:159-161.
12. El Shabrawi-Caelen L, Kerl H, Cerroni L. Lymphomatoid papulosis: reappraisal of clinicopathologic presentation and classification into subtypes A, B, and C. Arch Dermatol. 2004;140: 441-447.
13. Gerami P, Guitart J. The spectrum of histopathologic and immunohistochemical findings in folliculotropic mycosis fungoides. Am J Surg Pathol. 2007;31:1430-1438.
14. Hempstead RW, Ackerman AB. Follicular mucinosis. A reaction pattern in follicular epithelium. Am J Dermatopathol. 1985;7:245-257.
15. Jacobs MA, Kocher W, Murphy GF. Combined folliculotropic/ syringotropic cutaneous T-cell lymphoma without epidermal involvement: report of 2 cases and pathogenic implications. Hum Pathol. 2003;34:1216-1220.
16. Jaffe ES, Harris NL, Stein H, et al. World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissue. Lyon: IARC Press; 2001: 355 pages.
17. Jain S, Wyatt D, McCaughey C, et al. Nested multiplex polymerase chain reaction for the diagnosis of cutaneous herpes simplex and herpes zoster infections and a comparison with electron microscopy. J Med Virol. 2001;63:52-56.
18. Kazakov DV, Kutzner H, Palmedo G, et al. Primary cutaneous lymphoproliferative disorders with dual lineage rearrangement. Am J Dermatopathol. 2006;28:399-409.
19. Kazakov DV, Ondic O, Zamecnik M, et al. Morphological variations of scar-related and spontaneous endometriosis of the skin and superficial soft tissue: a study of 71 cases with emphasis on atypical features and types of mullerian differentiations. J Am Acad Dermatol. 2007;57:134-146.
20. + lymphoproliferative disorders: histopathology, differential diagnosis, new variants, and simulators. J Cutan Pathol. 2006;33(suppl 1):58-70.
21. Kibbi AG, Scrimenti RJ, Koenig RR, et al. A solitary nodule of the left cheek. Pseudolymphomatous folliculitis. Arch Dermatol. 1988; 124:1272-1273, 1276.
22. Kossard S, White A, Killingsworth M. Basaloid folliculolymphoid hyperplasia with alopecia as an expression of mycosis fungoides (CTCL). J Cutan Pathol. 1995;22:466-471.
23. LeBoit PE, Zackheim HS, White CR Jr. Granulomatous variants of cutaneous T-cell lymphoma. The histopathology of granulomatous mycosis fungoides and granulomatous slack skin. Am J Surg Pathol. 1988;12:83-95.
24. LeBoit PE. Granulomatous slack skin. Dermatol Clin. 1994;12:375-389.
25. Lee HW, Ahn SJ, Lee MW, et al. A case of pseudolymphomatous folliculitis. J Eur Acad Dermatol Venereol. 2006;20:230-232.
26. Leinweber B, Kerl H, Cerroni L. Histopathologic features of cutaneous herpes virus infections (herpes simplex, herpes varicella/ zoster): a broad spectrum of presentations with common pseudo-lymphomatous aspects. Am J Surg Pathol. 2006;30:50-58.
27. + lymphomatoid papulosis and its differential diagnosis. Am J Clin Pathol. 2006;125: 490-501.
28. Magro CM, Nash JW, Werling RW, et al. Primary cutaneous CD30+ large cell B-cell lymphoma: a series of 10 cases. Appl Immunohistochem Mol Morphol. 2006;14:7-11.
29. McNutt NS. Cutaneous lymphohistiocytic infiltrates simulating malignant lymphoma. In: Murphy GF, Mihm MC, eds. Lymphoproliferative Disorders of the Skin. Boston: Butterworths; 1986: 256-285.
30. Mehregan AH. Proliferation of sweat ducts in certain diseases of the skin. Am J Dermatopathol. 1981;3:27-31.
31. Palmedo G, Hantschke M, Rutten A, et al. Primary cutaneous marginal zone B-cell lymphoma may exhibit both the t(14;18)(q32;q21) IGH/ BCL2 and the t(14;18)(q32;q21) IGH/MALT1 translocation: an indicator for clonal transformation towards higher-grade B-cell lymphoma? Am J Dermatopathol. 2007;29:231-236.
32. Rongioletti F, Cerroni L, Massone C, et al. Different histologic patterns of cutaneous granulomas in systemic lymphoma. J Am Acad Dermatol. 2004;51:600-605.
33. Salhany KE, Macon WR, Choi JK, et al. Subcutaneous panniculitis-like T-cell lymphoma: clinicopathologic, immunophenotypic, and genotypic analysis of alpha/beta and gamma/delta subtypes. Am J Surg Pathol. 1998;22:881-893.
34. Scarabello A, Leinweber B, Ardigo M, et al. Cutaneous lymphomas with prominent granulomatous reaction: a potential pitfall in the histopathologic diagnosis of cutaneous T- and B-cell lymphomas. Am J Surg Pathol. 2002;26:1259-1268.
35. Servitje O, Gallardo F, Estrach T, et al. Primary cutaneous marginal zone B-cell lymphoma: a clinical, histopathological, immunopheno-typic and molecular genetic study of 22 cases. Br J Dermatol. 2002; 147:1147-1158.
36. Shapiro PE, Pinto FJ. The histologic spectrum of mycosis fungoides/Sezary syndrome (cutaneous T-cell lymphoma). A review of 222 biopsies, including newly described patterns and the earliest pathologic changes. Am J Surg Pathol. 1994;18:645-667.
37. Thein M, Ravat F, Orchard G, et al. Syringotropic cutaneous T-cell lymphoma: an immunophenotypic and genotypic study of five cases. Br J Dermatol. 2004;151:216-226.
38. van Dongen JJ, Langerak AW, Bruggemann M, et al. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia. 2003;17:2257-2317.
39. van Doorn R, Scheffer E, Willemze R. Follicular mycosis fungoides, a distinct disease entity with or without associated follicular mucinosis: a clinicopathologic and follow-up study of 51 patients. Arch Dermatol. 2002;138:191-198.
40. Willemze R, Jaffe ES, Burg G, et al. WHO-EORTC classification for cutaneous lymphomas. Blood. 2005;105:3768-3785.
41. Wongchaowart NT, Kim B, Hsi ED, et al. t(14;18)(q32;q21) involving IGH and MALT1 is uncommon in cutaneous MALT lymphomas and primary cutaneous diffuse large B-cell lymphomas. J Cutan Pathol. 2006;33:286-292.
42. Zelger B, Sepp N, Weyrer K, et al. Syringotropic cutaneous T-cell lymphoma: a variant of mycosis fungoides? Br J Dermatol. 1994; 130:765-769.