Melatonin improves tourniquet tolerance and enhances postoperative analgesia in patients receiving intravenous regional anesthesia

Anesthesia and Analgesia

Volumn 107, Issue 4, 2008, Pages 1422-1426

  Mowafi, Hany A ^a,b   Ismail, Salah A ^a  

^a KING FAISAL UNIVERSITY   (Saudi Arabia)

^b IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

DICLOFENAC; FENTANYL; LIDOCAINE; MELATONIN; PLACEBO; ANXIOLYTIC AGENT; CENTRAL DEPRESSANT AGENT; LOCAL ANESTHETIC AGENT;

ADULT; ANXIETY; ARTERIAL PRESSURE; ARTICLE; BRADYCARDIA; CLINICAL ARTICLE; CONTROL GROUP; CONTROLLED STUDY; CONVALESCENCE; DIZZINESS; DRUG EFFICACY; FEMALE; HEADACHE; HEART RATE; HEMODYNAMICS; HUMAN; HYPERTENSION; HYPOTENSION; HYPOXEMIA; MALE; NAUSEA; OXYGEN SATURATION; PAIN; PAIN ASSESSMENT; PAIN THRESHOLD; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RASH; REGIONAL ANESTHESIA; SOMNOLENCE; TACHYCARDIA; TINNITUS; TOURNIQUET; VOMITING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DOUBLE BLIND PROCEDURE; HAND; INTRAVENOUS DRUG ADMINISTRATION; NERVE BLOCK; PREMEDICATION; RANDOMIZED CONTROLLED TRIAL;

ADJUVANTS, ANESTHESIA; ADULT; ANESTHETICS, LOCAL; ANTI-ANXIETY AGENTS; DOUBLE-BLIND METHOD; FEMALE; HAND; HUMANS; INJECTIONS, INTRAVENOUS; LIDOCAINE; MALE; MELATONIN; NERVE BLOCK; PAIN; PAIN, POSTOPERATIVE; PREANESTHETIC MEDICATION; TOURNIQUETS;

EID: 53449100558     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ane.0b013e318181f689     Document Type: Article

References (23)

1. Brown EM, McGriff JT, Malinowski RW. Intravenous regional anaesthesia (Bier block): review of 20 years' experience. Can J Anaesth 1989;36:307-10
2. Jaakola ML. Dexmedetomidine premedication before intravenous regional anesthesia in minor outpatient hand surgery. J Clin Anesth 1994;6:204-11
3. Turan A, White PF, Karamanlioglu B, Pamukçu Z. Premedication with gabapentin: the effect on tourniquet pain and quality of intravenous regional anesthesia. Anesth Analg 2007;104:97-101
4. Naguib M, Gottumukkala V, Goldstein PA. Melatonin and anesthesia: a clinical perspective. J Pineal Res 2007;42:12-21
5. Yu CX, Zhu CB, Xu SF, Cao XD, Wu GC. The analgesic effects of peripheral and central administration of melatonin in rats. Eur J Pharmacol 2000;403:49-53
6. Bilici D, Akpinar E, Kiziltunc A. Protective effect of melatonin in carrageenan-induced acute local inflammation. Pharmacol Res 2002;46:133-9
7. El-Shenawy SM, Abdel-Salam OM, Baiuomy AR, El-Batran S, Arbid MS. Studies on the anti-inflammatory and anti-nociceptive effects of melatonin in the rat. Pharmacol Res 2002;46:235-43
8. Pang CS, Tsang SF, Yang JC. Effects of melatonin, morphine and diazepam on formalin-induced nociception in mice. Life Sci 2001;68:943-51
9. Caumo W, Torres F, Moreira NL Jr, Auzani JA, Monteiro CA, Londero G, Ribeiro DF, Hidalgo MP. The clinical impact of preoperative melatonin on postoperative outcomes in patients undergoing abdominal hysterectomy. Anesth Analg 2007; 105:1263-71
10. Reuben SS, Steinberg RB, Klatt Jl, Klatt ML. Intravenous regional anesthesia using lidocaine and clonidine. Anesthesiology 1999;91:654-8
11. Kindler CH, Harms C, Amsler F, Ihde-Scholl T, Scheidegger D. The Visual Analog Scale allows effective measurement of preoperative anxiety and detection of patients' anesthetic concerns. Anesth Analg 2000;90:706-12
12. Naguib M, Samarkandi AH. Premedication with melatonin: a double-blind, placebo controlled comparison with midazolam. Br J Anaesth 1999;82:875-80
13. Naguib M, Samarkandi AH. The comparative dose-response effect of melatonin and midazolam for premedication of adult's patients: a double-blinded placebo-controlled study. Anesth Analg 2000;91:473-9
14. Capuzzo M, Zanardi B, Schiffino E, Buccoliero C, Gragnaniello D, Bianchi S, Alvisi R. Melatonin does not reduce anxiety more than placebo in the elderly undergoing surgery. Anesth Analg 2006;103:121-3
15. Lowrie A, Jones MJ, Eastley RJ. Effect of a eutectic mixture of local anaesthetic agents (EMLA) on tourniquet pain in volunteers. Br J Anaesth 1989;63:751-3
16. Mense S. Nociception from skeletal muscle in relation to clinical muscle pain. Pain 1993;54:241-89
17. Kokki H, Väätäinen U, Penttilä I. Metabolic effects of a lowpressure tourniquet system compared with a high-pressure tourniquet system in arthroscopic anterior crucial ligament reconstruction. Acta Anaesthesiol Scand 1998;42:418-24
18. Laurido C, Pelissie T, Soto-Moyano R, Valladares L, Flores F, Herna'ndez A. Effect of melatonin on rat spinal cord nociceptive transmission. Neuroreport 2002;13:89-91
19. Noseda R, Herna'ndez A, Valladares L, Mondaca M, Laurido C, Soto-Moyano R. Melatonin-induced inhibition of spinal cord synaptic potentiation in rats is MT2 receptor-dependent. Neurosci Lett 2004;360:41-4
20. Ambriz-Tututi M, Granados-Soto V. Oral and spinal melatonin reduces tactile allodynia in rats via activation of MT2 and opioid receptors. Pain 2007;132:273-80
21. Ulugol A, Dokmeci D, Guray G, Sapolyo N, Ozyigit F, Tamer M. Antihyperalgesic, but not antiallodynic, effect of melatonin in nerve-injured neuropathic mice: possible involvements of the l-arginine-NO pathway and opioid system. Life Sci 2006; 78:1592-7
22. Yu CX, Zhu CB, Xu SF, Cao XD, Wu GC. Selective MT2 melatonin receptor antagonist blocks melatonin-induced antinociception in rats. Neurosci Lett 2000;282:161-4
23. Mantovani M, Kaster MP, Pertile R, Calixto JB, Rodrigues AL, Santos AR. Mechanisms involved in the antinociception caused by melatonin in mice. J Pineal Res 2006;41:382-9