MOTHERISK ROUNDS: Medications for Restless Legs Syndrome in Pregnancy

Journal of Obstetrics and Gynaecology Canada

Volumn 30, Issue 6, 2008, Pages 505-507

  Djokanovic, Nada ^a   Garcia Bournissen, Facundo ^a   Koren, Gideon ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Antiepileptics; Benzodizepines; Dopaminergics; Opioids; Pregnancy; Restless legs syndrome

Indexed keywords

ANTICONVULSIVE AGENT; BENZODIAZEPINE DERIVATIVE; CARBAMAZEPINE; CLONAZEPAM; DOPAMINE RECEPTOR STIMULATING AGENT; FERRITIN; FOLIC ACID; GABAPENTIN; IRON; LEVODOPA; OPIATE; PRAMIPEXOLE; ROPINIROLE; TEMAZEPAM; TRIAZOLAM; NARCOTIC ANALGESIC AGENT; TERATOGENIC AGENT;

ARTICLE; DOPAMINERGIC SYSTEM; DRUG EFFICACY; DRUG SAFETY; FERRITIN BLOOD LEVEL; HOMEOSTASIS; HUMAN; IRON HOMEOSTASIS; PARKINSON DISEASE; PATHOPHYSIOLOGY; PREGNANCY; QUALITY OF LIFE; RESTLESS LEGS SYNDROME; RISK ASSESSMENT; SUPPLEMENTATION; SYMPTOMATOLOGY; TERATOGENICITY; ADULT; CHEMICALLY INDUCED DISORDER; FEMALE; PREGNANCY COMPLICATION; PRENATAL EXPOSURE; RISK FACTOR;

ADULT; ANALGESICS, OPIOID; ANTICONVULSANTS; BENZODIAZEPINES; DOPAMINE AGONISTS; FEMALE; HUMANS; IRON; PREGNANCY; PREGNANCY COMPLICATIONS; PRENATAL EXPOSURE DELAYED EFFECTS; RESTLESS LEGS SYNDROME; RISK FACTORS; TERATOGENS;

EID: 53449091102     PISSN: 17012163     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1701-2163(16)32866-3     Document Type: Article

References (36)

1. Kushida C., Martin M., Nikam P., Blasidell B., Wallenstein G., Ferini-Strambi L., et al. Burden of restless legs syndrome on health-related quality of life. Qual Life Res 2007, 16(4):617-624.
2. Abetz L., Allen R., Follet A., Washburn T., Earley C., Kirsch J., et al. Evaluating the quality of life of patients with restless legs syndrome. Clin Ther 2004, 26(6):925-935.
3. Garcia-Borreguero D., Egatz R., Winkelmann J., Berger K. Epidemiology of restless legs syndrome: the current status. Sleep Med Rev 2006, 10:153-167.
4. Gamaldo C.E., Earley C.J. Restless legs syndrome: a clinical update. Chest 2006, 130(5):1596-1604.
5. Allen R.P., Picchietti D., Hening W.A., Trenkwalder C., Walters A.S., Montplaisi J. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the Restless Legs Syndrome Diagnosis and Epidemiology Workshop at the National Institutes of Health. Sleep Med 2003, 4:101-119.
6. Garcia-Borreguero Time to REST: epidemiology and burden. Eur J Neurol 2006, 13:15-20.
7. Pearce J.M.S. Restless leg syndrome. Eur J Neurol 2005, 53:206-207.
8. Winkelman J.W. Considering the causes of RLS. Eur J Neurol 2006, 13(Suppl. 2):8-14.
9. Trenkwalder C., Paulus W., Walters A. The restless legs syndrome. Lancet Neurol 2005, 4:465-475.
10. Allen R.P. Controversies and challenges in defining the etiology and pathophysiology of restless legs syndrome. Am J Med 2007, 120(1 A):S13-S21.
11. Ekbom K.A. Restless legs syndrome. Acta Med Scand 1945, 158:4-122.
12. Jolivet B. Paresthésies agitantes nocturnes des membres inférieurs, impatiences 1953, Thése de Paris.
13. Goodman J.D., Brodie C., Ayida G.A. Restless leg syndrome in pregnancy. BMJ 1988, 297:1101-1102.
14. Manconi M., Govoni V., De Vito A., Economou N.T., Cesnic E., Mollica G., et al. Pregnancy as a risk factor for restless legs syndrome. Sleep Med 2004, 5:305-308.
15. Allen R.P., Walters A.S., Montplaisir J., Hening W., Myers A., Bell T.J., et al. Restless legs syndrome prevalence and impact: REST general population study. Arch Intern Med 2005, 165(11):1286-1292.
16. Mucchiut M., Belgrado E., Cutuli D., Antonini A., Bergonzi P. Pramipexole-treated Parkinson's disease during pregnancy. Mov Disord 2004, 19(9):1114-1115.
17. Scott M., Chowdhury M. Pregnancy in Parkinson's disease: unique case report and review of the literature. Mov Disord 2005, 20(8):1078-1079.
18. Walters A.S., Wagner M.L., Hening W.A., Grasing K., Mills R., Chokroverty S., et al. Successful treatment of the idiopathic restless legs syndrome in a randomized double-blind trial of oxycodone versus placebo. Sleep 1993, 16:327-332.
19. Lauerma H., Markkula J. Treatment of restless legs syndrome with tramadol: an open study. J Clin Psychiatry 1999, 60:241-244.
20. Ondo W.G. Methadone for refractory restless legs syndrome. Mov Disord 2005, 20:345-348.
21. Mangurten H.H., Benawra R. Neonatal codeine withdrawal in infants of non-addicted mothers. Pediatrics 1980, 65:159-160.
22. Klein R.B., Blatman S., Little G.A. Probable neonatal propoxyphene withdrawal: a case report. Pediatrics 1975, 55:882-884.
23. Willis T. De anima brutorum 1672, Wells and Scot, London.
24. Phillips B. Movement disorders. A sleep specialist's perspective. Neurology 2004, 62(Suppl 2):S9-S16.
25. Hening W.A. Current guidelines and standards of practice for restless legs syndrome. Am J Med 2007, 120(1A):S22-S27.
26. Walters A.S., Winkelmann J., Trenkwalder C., Fry J.M., Kataria V., Wagner M., et al. Long-term follow-up on restless legs syndrome patients treated with opioids. Mov Disord 2001, 16(6):1105-1109.
27. Manconi M., Ferini-Strambi L., Hening W.A. Response to Clinical Corners case (Sleep Medicine 6/2:83-4): pregnancy associated with daytime sleepiness and nighttime restlessness. Sleep Med 2005, 6:477-478.
28. Dolovich L.R., Addis A., Vaillancourt J.M., Power J.D., Koren G., Einarson T.R. Benzodiazepine use in pregnancy and major malformations or oral cleft: meta-analysis of cohort and case-control studies. BMJ 1998, 317:839-843.
29. Gillberg C. "Floppy infant syndrome" and maternal diazepam. Lancet 1977, 2:244.
30. Saletu M., Anderer P., Saletu-Zyhlarz G., Prause W., Semler B., Zoghlami A., et al. Restless legs syndrome (RLS) and periodic limb movement disorder (PLMD): acute placebo-controlled sleep laboratory studies with clonazepam. Eur Neuropsychopharmacol 2001, 11:153-161.
31. Garcia-Borreguero D., Larrosa O., de la Llave Y., Verger K., Masramon X., Hernandez G. Treatment of restless legs syndrome with gabapentin: a double-blind, cross-over study. Neurology 2002, 59:1573-1579.
32. Happe S., Sauter C., Klosch G., Saletu B., Zeitlhofer J., et al. Gabapentin versus ropinirole in the treatment of idiopathic restless legs syndrome. Neuropsychobiology 2003, 48:82-86.
33. Montouris G. Gabapentin exposure in human pregnancy: results from the Gabapentin Pregnancy Registry. Epilepsy Behav 2003, 4:310-317.
34. Telstad W., Sørensen O., Larsen S., Lillevold P.E., Stensrud P., Nyberg-Hansen R. Treatment of the restless legs syndrome with carbamazepine: a double blind study. BMJ 1984, 288:444-446.
35. Morrow J., Russell A., Guthrie E., Parsons L., Robertson I., Waddell R., et al. Malformation risks of antiepileptic drugs in pregnancy: a prospective study from the UK Epilepsy and Pregnancy Register. J Neurol Neurosurg Psychiatry 2006, 77:193-198.
36. Sun E.R., Chen C.A., Ho G., Early C.J., Allen R.P. Iron and the restless legs syndrome. Sleep 1998, 21:371-377.