Stuttering priapism complicating Warfarin therapy in a patient with protein C deficiency

International Journal of Laboratory Hematology

Volumn 30, Issue 4, 2008, Pages 339-343

  Abu Sham'a, R A H ^a   Kufri, F H ^a   Yassin, I H ^a  

^a Al Makassed Islamic Charitable Society Hospital   (Israel)

Author keywords

Priapism; Protein C deficiency; Thrombophilia; Warfarin; Warfarin induced skin necrosis

Indexed keywords

DOLOSTIN; ENOXAPARIN; HEPARIN; PETHIDINE; PROTEIN C; UNCLASSIFIED DRUG; WARFARIN; ANTICOAGULANT AGENT;

ADULT; ANTICOAGULANT THERAPY; ARTICLE; CASE REPORT; CLINICAL FEATURE; CONSERVATIVE TREATMENT; CONTINUOUS INFUSION; DEEP VEIN THROMBOSIS; DRUG SUBSTITUTION; DRUG WITHDRAWAL; GENERAL PRACTITIONER; HOSPITAL READMISSION; HUMAN; LOADING DRUG DOSE; MALE; PARTIAL THROMBOPLASTIN TIME; PHLEBOGRAPHY; PRIAPISM; PRIORITY JOURNAL; PROTEIN C DEFICIENCY; RECURRENT DISEASE; SKIN NECROSIS; LUNG EMBOLISM; VEIN THROMBOSIS;

ADULT; ANTICOAGULANTS; ENOXAPARIN; HUMANS; MALE; PRIAPISM; PROTEIN C DEFICIENCY; PULMONARY EMBOLISM; VENOUS THROMBOSIS; WARFARIN;

EID: 53449083250     PISSN: 17515521     EISSN: 1751553X     Source Type: Journal    
DOI: 10.1111/j.1751-553X.2007.00963.x     Document Type: Article

References (23)

1. Beitz J.M. (2002) Coumadin-induced skin necrosis. Wounds 14, 217-226.
2. Broderick G.A. & Lue T.F. (2002) Evaluation and nonsurgical management of erectile dysfunction and piapism. In: Campbell's Urology (eds P.C. Walsh, A.B. Retik, E.D. Vaughan Jr & A.J. Wein), Vol 2, 8th edn, pp. 1619-1671 Philadelphia, WB Saunders.
3. Daryanani S. & Wilde J.T. (1997) Priapism in a patient with protein C deficiency. Clinical and Laboratory Haematology 19, 213-214.
4. Eland I.A., van der Lei J., Stricker B.H. & Sturkenboom M.J. (2001) Incidence of priapism in the general population. Urology 57, 970-972.
5. Francis R.B. (1985) The protein C anticoagulant pathway and thrombosis. Western Journal of Medicine 143, 95-96.
6. Gailani D. & Reese E.P. Jr (1999) Anticoagulant-induced skin necrosis in a patient with hereditary deficiency of protein S. American Journal Hematology 60, 231-236.
7. Goto T., Yagi S., Matsushita S., Uchida Y., Kawahara M. & Ohi Y. (1999) Diagnosis and treatment of priapism: experience with 5 cases. Urology 53, 1019-1023.
8. Kearon C., Crowther M. & Hirsh J. (2000) Management of hereditary hypercoagulable disorders. Annual Review of Medicine 51, 169-185.
9. Keoghane S.R., Sullivan M.E. & Miller M.A. (2002) The aetiology, pathogenesis and management of priapism. BJU International 90, 149-154.
10. Lam T.B.L., Sundaram S.K. & Wright D. (2001) Recurrent spontaneous priapism in a patient with protein C deficiency and Klippel-Trenaunay-Weber syndrome. BJU International 87, 126.
11. Lane D.A., Mannucci P.M., Bauer K.A., Bertina R.M., Bochkov N.P., Boulyjenkov V., Chandy M., Dahlback B., Ginter E.K., Miletich J.P., Rosendaal F.R. & Seliqsohn U. (1996) Inherited thrombophilia: part 1. Thrombosis Haemostasis 76, 651-662.
12. Loeliger E.A., van der Esch M., Mattern M.J. & den Brabander A.S. (1963) Behaviour of factors II, VII, IX, and X during long-term treatment with coumarin. Thrombosis et Diathesis Haemorrhagica 9, 74-89.
13. Mahapatra M., Bhattacharya M., Mishra P., Kumar R. & Saxena R. (2006) Priapism: an unusual manifestation of Warfarin-induced skin necrosis with protein C deficiency. The Journal of the Association of Physicians of India 54, 963-964.
14. Melissari E. & Kakkar V.V. (1989) Congenital severe protein C deficiency in adults. British Journal of Haematology 72, 222-228.
15. Montague D.K., Jarow J., Broderick G.A., Dmochowski R.R., Heaton J.P., Lue T.F., Nehra A. & Sharlip I.D. (2003) Members of the erectile dysfunction guideline update panel; American Urological Association. American Urological Association Guideline on the Management of Priapism. Journal of Urology 170, 1318-1324.
16. Nelson J.H. III & Winter C.C. (1977) Priapism: evolution in management in 48 patients in a 22-year series. The Journal of Urology 117, 455-458.
17. Sadeghi-Nejad H. & Seftel A.D. (2002) The etiology, diagnosis, and treatment of priapism: review of the American Foundation for Urologic Disease Consensus Panel Report. Current Urology Reports 3, 492-498.
18. Spycher M.A. & Hauri D. (1986) The ultrastructure of erectile tissue in priapism. The Journal of Urology 135, 142-147.
19. Tait R.C., Walker I.D., Reitsma P.H., Islam S.I., McCall F., Poort S.R., Conkie J.A. & Bertina R.M. (1995) Prevalence of protein C in healthy population. Thrombosis and Haemostasis 73, 87-93.
20. Touloupidis S., Zoumpos I., Kalaitzis C., Vogiatzaki T. & Chloropoulou P. (2004) Acenocoumarol associated priapism: report of a case. Andrologia 36, 47-49.
21. Vilke G.M., Harrigan R.A., Ufberg J.W. & Chan T.C. (2004) Emergency evaluation and treatment of priapism. The Journal of Emergency Medicine 26, 325-329.
22. Weiss P., Soff G.A., Halkin H. & Seligsohn U. (1987) Decline of proteins C and S and factors II, VII, IX and X during the initiation of warfarin therapy. Thrombosis Research 15, 45 783-790.
23. Zimbelman J., Lefkowitz J., Schaeffer C., Hays T., Manco-Johnson M., Manhalter C. & Nuss R. (2000) Unusual complication of warfarin therapy: skin necrosis and priapism. The Journal of Pediatrics 137, 266-268.