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Volumn 43, Issue 35, 2004, Pages 4554-4556

Organic protein chemistry: Drug discovery through the chemical modification of proteins

Author keywords

Chemical ligation; Drug discovery; Medicinal chemistry; Proteins

Indexed keywords

BINDING ENERGY; CHEMICAL MODIFICATION; DRUG PRODUCTS; ORGANIC COMPOUNDS;

EID: 5344229414     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200460075     Document Type: Short Survey
Times cited : (28)

References (14)
  • 6
    • 5344248950 scopus 로고    scopus 로고
    • note
    • Yields of 15-30% were reported for the peptide synthesis and ligation, 30-50% for the oxime ligation, 40-70% for the thioester ligation, and 25-40% for the folding. This gives an overall yield of between 0.072 and 2% without consideration of losses in yield during peptide synthesis.
  • 10
    • 0347230974 scopus 로고    scopus 로고
    • S. Weik, J. Rademann, Angew. Chem. 2003, 115, 2595-2598; Angew. Chem. Int. Ed. 2003, 42, 2491-2494.
    • (2003) Angew. Chem. , vol.115 , pp. 2595-2598
    • Weik, S.1    Rademann, J.2
  • 11
    • 0037860931 scopus 로고    scopus 로고
    • S. Weik, J. Rademann, Angew. Chem. 2003, 115, 2595-2598; Angew. Chem. Int. Ed. 2003, 42, 2491-2494.
    • (2003) Angew. Chem. Int. Ed. , vol.42 , pp. 2491-2494


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.