-
1
-
-
0028798939
-
A double-blind comparison of Org 3770, amitriptyline, and placebo in major depression
-
Bremner JD (1995) A double-blind comparison of Org 3770, amitriptyline, and placebo in major depression. J Clin Psychiatr 56:519-525
-
(1995)
J Clin Psychiatr
, vol.56
, pp. 519-525
-
-
Bremner, J.D.1
-
2
-
-
0029070521
-
A double-blind placebo-controlled study of mirtazapine in depressed outpatients
-
Claghorn JL, Lesem MD (1995) A double-blind placebo-controlled study of mirtazapine in depressed outpatients. J Affect Disord 34:165-171
-
(1995)
J Affect Disord
, vol.34
, pp. 165-171
-
-
Claghorn, J.L.1
Lesem, M.D.2
-
3
-
-
0025082572
-
Mirtazapine vs. amitriptyline vs. placebo in the treatment of major depression
-
Smith WT, Glaudin V, Panagides J, Gilvary E (1990) Mirtazapine vs. amitriptyline vs. placebo in the treatment of major depression. Psychopharmacol Bull 26:191-196
-
(1990)
Psychopharmacol Bull
, vol.26
, pp. 191-196
-
-
Smith, W.T.1
Glaudin, V.2
Panagides, J.3
Gilvary, E.4
-
4
-
-
5344246257
-
A randomised, double-blind, placebo-controlled, 5-weeks' study of mirtazapine and placebo in hospitalized patients with major depression
-
Khan MC (1994) A randomised, double-blind, placebo-controlled, 5-weeks' study of mirtazapine and placebo in hospitalized patients with major depression. Eur Neuropsychopharmacol 4:145-150
-
(1994)
Eur Neuropsychopharmacol
, vol.4
, pp. 145-150
-
-
Khan, M.C.1
-
5
-
-
0028237797
-
Double-blind study of mirtazapine and placebo in hospitalized patients with major depression
-
Vartiainen H, Leinonen E (1994) Double-blind study of mirtazapine and placebo in hospitalized patients with major depression. Eur Neuropsychopharmacol 4:145-150
-
(1994)
Eur Neuropsychopharmacol
, vol.4
, pp. 145-150
-
-
Vartiainen, H.1
Leinonen, E.2
-
6
-
-
0029010292
-
Mirtazapine versus amitriptyline: A 6-week randomized double-blind multicentre trial in hospitalized depressed patients
-
Zivkov M, de Jongh GD (1995) Mirtazapine versus amitriptyline: a 6-week randomized double-blind multicentre trial in hospitalized depressed patients. Hum Psychopharmacol 10:173-180
-
(1995)
Hum Psychopharmacol
, vol.10
, pp. 173-180
-
-
Zivkov, M.1
De Jongh, G.D.2
-
7
-
-
0029745693
-
A multicentre, double-blind, amitriptyline-controlled study of mirtazapine in patients with major depression
-
Mullin J, Lodge A, Bennie E, McCready R, Singh Batt G, Fenton G (1996) A multicentre, double-blind, amitriptyline-controlled study of mirtazapine in patients with major depression. J Psychopharmacol 10:235-240
-
(1996)
J Psychopharmacol
, vol.10
, pp. 235-240
-
-
Mullin, J.1
Lodge, A.2
Bennie, E.3
McCready, R.4
Singh Batt, G.5
Fenton, G.6
-
8
-
-
0029118693
-
A multicentre, double-blind, clomipramine-controlled efficacy and safety study of mirtazapine
-
Richou H, Ruimy P, Charbaut J, Delisle JP, Brunner H, Patris M (1995) A multicentre, double-blind, clomipramine-controlled efficacy and safety study of mirtazapine. Hum Psychopharmacol 10:263-271
-
(1995)
Hum Psychopharmacol
, vol.10
, pp. 263-271
-
-
Richou, H.1
Ruimy, P.2
Charbaut, J.3
Delisle, J.P.4
Brunner, H.5
Patris, M.6
-
9
-
-
0028792322
-
A double-blind study comparing the efficacy and tolerability of mirtazapine and doxepin in patients with major depression
-
Marttila M, Jääskelainen J, Järvi R, Romanov M, Miettinen E, Sorri P, Ahlfors U, Zivkov M (1995) A double-blind study comparing the efficacy and tolerability of mirtazapine and doxepin in patients with major depression. Eur Neuropsychopharmacol 6:441-446
-
(1995)
Eur Neuropsychopharmacol
, vol.6
, pp. 441-446
-
-
Marttila, M.1
Jääskelainen, J.2
Järvi, R.3
Romanov, M.4
Miettinen, E.5
Sorri, P.6
Ahlfors, U.7
Zivkov, M.8
-
11
-
-
0029074770
-
Pharmacokinetic dose-proportionality study at steady-state of mirtazapine from Remeron® tablets
-
Timmer CJ, Lohmann AAM, Mink CPA (1995) Pharmacokinetic dose-proportionality study at steady-state of mirtazapine from Remeron® tablets. Hum Psychopharmacol 10:S97-S106
-
(1995)
Hum Psychopharmacol
, vol.10
-
-
Timmer, C.J.1
Lohmann, A.A.M.2
Mink, C.P.A.3
-
12
-
-
0030724679
-
A risk-benefit assessment of mirtazapine in the treatment of depression
-
Kasper S, Praschak-Rieder N, Tauscher J, Wolf R (1997) A risk-benefit assessment of mirtazapine in the treatment of depression. Drug Saf 17:251-64
-
(1997)
Drug Saf
, vol.17
, pp. 251-264
-
-
Kasper, S.1
Praschak-Rieder, N.2
Tauscher, J.3
Wolf, R.4
-
13
-
-
0037904925
-
Therapeutisches drug-monitoring von anti-depressiva-therapeutischer und gesundheitsökonomischer nutzen
-
Grasmäder K, Lohmann PL, Kuss HJ, Laux G, Hiemke C, Rao ML (2003) Therapeutisches Drug-Monitoring von Anti-depressiva-therapeutischer und gesundheitsökonomischer Nutzen. Med Mol Pharm 26:162-164
-
(2003)
Med Mol Pharm
, vol.26
, pp. 162-164
-
-
Grasmäder, K.1
Lohmann, P.L.2
Kuss, H.J.3
Laux, G.4
Hiemke, C.5
Rao, M.L.6
-
15
-
-
0041846678
-
Determination of eighteen antidepressants, four antipsychotics and active metabolites in serum by liquid chromatography: A simple tool for therapeutic drug monitoring
-
Frahnert C, Rao ML, Grasmäder K (2003) Determination of eighteen antidepressants, four antipsychotics and active metabolites in serum by liquid chromatography: a simple tool for therapeutic drug monitoring. J Chromatogr B Biomed Sci Appl 794:35-47
-
(2003)
J Chromatogr B Biomed Sci Appl
, vol.794
, pp. 35-47
-
-
Frahnert, C.1
Rao, M.L.2
Grasmäder, K.3
-
16
-
-
0028998678
-
Phenotyping of CYP2C19 with enantiospecific HPLC-quantification of R- and S-mephenytoin and comparison with the intron4/exon5 G-> A-splice site mutation
-
Brockmöller J, Rost KL, Gross D, Schenkel A, Roots I (1995) Phenotyping of CYP2C19 with enantiospecific HPLC-quantification of R- and S-mephenytoin and comparison with the intron4/exon5 G-> A-splice site mutation. Pharmacogenetics 5:80-88
-
(1995)
Pharmacogenetics
, vol.5
, pp. 80-88
-
-
Brockmöller, J.1
Rost, K.L.2
Gross, D.3
Schenkel, A.4
Roots, I.5
-
17
-
-
0028260641
-
The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans
-
de Morais SM, Wilkinson GR, Blaisdell J, Nakamura K, Meyer UA, Goldstein JA (1994) The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans. J Biol Chem 269:15419-15422
-
(1994)
J Biol Chem
, vol.269
, pp. 15419-15422
-
-
De Morais, S.M.1
Wilkinson, G.R.2
Blaisdell, J.3
Nakamura, K.4
Meyer, U.A.5
Goldstein, J.A.6
-
18
-
-
0029622336
-
An efficient strategy for detection of known and new mutations of the CYP2D6 gene using single strand conformation polymorphism analysis
-
Broly F, Marez D, Sabbagh N, Legrand M, Millecamps S, Lo Guidice JM, Boone P, Meyer UA (1995) An efficient strategy for detection of known and new mutations of the CYP2D6 gene using single strand conformation polymorphism analysis. Pharmacogenetics 5:373-384
-
(1995)
Pharmacogenetics
, vol.5
, pp. 373-384
-
-
Broly, F.1
Marez, D.2
Sabbagh, N.3
Legrand, M.4
Millecamps, S.5
Lo Guidice, J.M.6
Boone, P.7
Meyer, U.A.8
-
19
-
-
0029102348
-
Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology
-
Steen VM, Andreassen OA, Daly AK, Tefre T, Borresen AL, Idle JR, Gulbrandsen AK (1995) Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology Pharmacogenetics 5:215-223
-
(1995)
Pharmacogenetics
, vol.5
, pp. 215-223
-
-
Steen, V.M.1
Andreassen, O.A.2
Daly, A.K.3
Tefre, T.4
Borresen, A.L.5
Idle, J.R.6
Gulbrandsen, A.K.7
-
20
-
-
0007293059
-
Ultrarapid metabolizers of debrisoquine: Characterization and PCR-based detection of alleles with duplication of the CYP2D6 gene
-
Løvlie R, Daly AK, Molven A., Idle JR, Steen VM (1996) Ultrarapid metabolizers of debrisoquine: characterization and PCR-based detection of alleles with duplication of the CYP2D6 gene. FEBS Lett 392:30-34
-
(1996)
FEBS Lett
, vol.392
, pp. 30-34
-
-
Løvlie, R.1
Daly, A.K.2
Molven, A.3
Idle, J.R.4
Steen, V.M.5
-
21
-
-
5344280788
-
-
Pharsight Cooperation, Mountain View, California
-
WinNonMix™ Reference Guide (1999) Pharsight Cooperation, Mountain View, California
-
(1999)
WinNonMix™ Reference Guide
-
-
-
22
-
-
0016922835
-
Quick estimation of the absorption rate constant for clinical purposes using a nomograph
-
Franke EK, Ritschel WA (1976) Quick estimation of the absorption rate constant for clinical purposes using a nomograph. Drug Intel Clin Pharm 10:77-82
-
(1976)
Drug Intel Clin Pharm
, vol.10
, pp. 77-82
-
-
Franke, E.K.1
Ritschel, W.A.2
-
23
-
-
0029028790
-
Bioavailability of mirtazapine from Remeron® tablets after single and multiple oral dosing
-
Voortman G, Paanakker JE (1995) Bioavailability of mirtazapine from Remeron® tablets after single and multiple oral dosing. Hum Psychopharmacol 10[Suppl]:83-96
-
(1995)
Hum Psychopharmacol
, vol.10
, Issue.SUPPL.
, pp. 83-96
-
-
Voortman, G.1
Paanakker, J.E.2
-
24
-
-
0027049043
-
Building population pharmacokinetic-pharmacodynamic models. I. Models for covariate effects
-
Mandema JW, Verotta D, Sheiner LB (1992) Building population pharmacokinetic-pharmacodynamic models. I. Models for covariate effects. J Pharmacokinet Biopharm. 20:511-528
-
(1992)
J Pharmacokinet Biopharm
, vol.20
, pp. 511-528
-
-
Mandema, J.W.1
Verotta, D.2
Sheiner, L.B.3
-
25
-
-
0031884233
-
Assessment of the predictive power of genotypes for the in-vivo catalytic function of CYP2D6 in a German population
-
Griese EU, Zanger UM, Brudermanns U, Gaedigk A, Mikus G, Mörike K, Stuven T, Eichelbaum M (1998) Assessment of the predictive power of genotypes for the in-vivo catalytic function of CYP2D6 in a German population. Pharmacogenetics 8:15-26
-
(1998)
Pharmacogenetics
, vol.8
, pp. 15-26
-
-
Griese, E.U.1
Zanger, U.M.2
Brudermanns, U.3
Gaedigk, A.4
Mikus, G.5
Mörike, K.6
Stuven, T.7
Eichelbaum, M.8
-
26
-
-
0034283762
-
Influence of cytochrome P-450 CYP2C9 polymorphisms on warfarin sensitivity and risk of over-anticoagulation in patients on long-term treatment
-
Taube J, Halsall D, Baglin T (2000) Influence of cytochrome P-450 CYP2C9 polymorphisms on warfarin sensitivity and risk of over-anticoagulation in patients on long-term treatment. Blood 96:1816-1819
-
(2000)
Blood
, vol.96
, pp. 1816-1819
-
-
Taube, J.1
Halsall, D.2
Baglin, T.3
-
27
-
-
0032716358
-
Allelic, genotypic and phenotypic distributions of S-mephenytoin 4′-hydroxylase (CYP2C19) in healthy Caucasian populations of European descent throughout the world
-
Xie HG, Stein CM, Wilkinson GR, Flockhart DA, Wood AJ (1999) Allelic, genotypic and phenotypic distributions of S-mephenytoin 4′-hydroxylase (CYP2C19) in healthy Caucasian populations of European descent throughout the world. Pharmacogenetics 9:539-549
-
(1999)
Pharmacogenetics
, vol.9
, pp. 539-549
-
-
Xie, H.G.1
Stein, C.M.2
Wilkinson, G.R.3
Flockhart, D.A.4
Wood, A.J.5
-
28
-
-
0030460935
-
Pharmacokinetics of mirtazapine from orally administered tablets: Influence of gender, age and treatment regimen
-
Timmer CJ, Paanàkker JE, van Hal HJM (1996) Pharmacokinetics of mirtazapine from orally administered tablets: influence of gender, age and treatment regimen. Hum Psychopharmacol 11:497-509
-
(1996)
Hum Psychopharmacol
, vol.11
, pp. 497-509
-
-
Timmer, C.J.1
Paanàkker, J.E.2
Van Hal, H.J.M.3
-
29
-
-
0031930087
-
Pharmacokinetics and biotransformation of mirtazapine in healthy volunteers
-
Delbressine LPC, Moonen MEG, Kaspersen FM, Wagenaars GN, Jacobs PL, Timmer CJ, Paanakker JE, van Hal HJM, Voortman G (1998) Pharmacokinetics and biotransformation of mirtazapine in healthy volunteers. Clin Drug Invest 15:45-55
-
(1998)
Clin Drug Invest
, vol.15
, pp. 45-55
-
-
Delbressine, L.P.C.1
Moonen, M.E.G.2
Kaspersen, F.M.3
Wagenaars, G.N.4
Jacobs, P.L.5
Timmer, C.J.6
Paanakker, J.E.7
Van Hal, H.J.M.8
Voortman, G.9
-
30
-
-
0033810675
-
Metabolism of the antidepressant mirtazapine in vitro: Contribution of cytochromes P-450 1A2, 2D6 and 3A4
-
Stornier E, von Moltke LL, Shader RI, Greenblatt DJ (2000) Metabolism of the antidepressant mirtazapine in vitro: contribution of cytochromes P-450 1A2, 2D6 and 3A4. Drug Metab Dispos 28:1168-1175
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 1168-1175
-
-
Stornier, E.1
Von Moltke, L.L.2
Shader, R.I.3
Greenblatt, D.J.4
-
31
-
-
0033790979
-
Elucidation of the genetic basis of the common 'intermediate metabolizer' phenotype for drug oxidation by CYP2D6
-
Raimundo S, Fischer J, Eichelbaum M, Griese EU, Schwab M, Zanger UM (2000) Elucidation of the genetic basis of the common 'intermediate metabolizer' phenotype for drug oxidation by CYP2D6. Pharmacogenetics 10:577-581
-
(2000)
Pharmacogenetics
, vol.10
, pp. 577-581
-
-
Raimundo, S.1
Fischer, J.2
Eichelbaum, M.3
Griese, E.U.4
Schwab, M.5
Zanger, U.M.6
-
32
-
-
0031029475
-
In vitro and in vivo studies on the disposition of mirtazapine in humans
-
Dahl ML, Voortman G, Aim C, Elwin CE, Delbressine L, Vos R, Bogaards JJP, Bertilson L (1997) In vitro and in vivo studies on the disposition of mirtazapine in humans. Clin Drug Invest 13:37-46
-
(1997)
Clin Drug Invest
, vol.13
, pp. 37-46
-
-
Dahl, M.L.1
Voortman, G.2
Aim, C.3
Elwin, C.E.4
Delbressine, L.5
Vos, R.6
Bogaards, J.J.P.7
Bertilson, L.8
-
33
-
-
0034794112
-
Fluvoxamine augmentation increases serum mirtazapine concentrations three- to fourfold
-
Anttila SAK, Rasanen I, Leinonen EVJ (2001) Fluvoxamine augmentation increases serum mirtazapine concentrations three- to fourfold. Ann Pharmacother 35:1221-1223
-
(2001)
Ann Pharmacother
, vol.35
, pp. 1221-1223
-
-
Anttila, S.A.K.1
Rasanen, I.2
Leinonen, E.V.J.3
|