Observational study of sublingual specific immunotherapy persistent and intermittent allergic rhinitis: The EFESO trial

Current Medical Research and Opinion

Volumn 24, Issue 9, 2008, Pages 2719-2724

  Milani, Massimo ^a   Pecora, Silvia ^a   Burastero, Samuele ^b  

^a ALK Abello SpA   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

Allergic rhinitis; Asthma prevention; Case control trial; Sublingual immunotherapy

Indexed keywords

ALLERGEN; ANTIHISTAMINIC AGENT; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID; SLITONE; UNCLASSIFIED DRUG;

ADULT; ALLERGENICITY; ALLERGIC RHINITIS; ARTICLE; ASTHMA; CASE CONTROL STUDY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; DRUG TARGETING; FEMALE; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOMODULATION; IMMUNOREACTIVITY; IMMUNOTHERAPY; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OBSERVATIONAL STUDY; POLLEN ALLERGY; RHINOCONJUNCTIVITIS; SIDE EFFECT; SKIN SENSITIZATION;

ADULT; CASE-CONTROL STUDIES; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; IMMUNOTHERAPY; MALE; RHINITIS, ALLERGIC, PERENNIAL;

EID: 53349173860     PISSN: 03007995     EISSN: None     Source Type: Journal    
DOI: 10.1185/03007990802366639     Document Type: Article

References (21)

1. Bousquet J. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update. Allergy 2008;63(Suppl 86):8-160
2. Canonica GW, Passalacqua G. Noninjection routes for immunotherapy. J Allergy Clin Immunol 2003;111:437-48
3. Dahl R, Kapp A, Colombo G, et al. Efficacy and safety of sublingual immunotherapy with grass allergen tablets for seasonal allegic rhinoconjunctivitis. J Allergy Clin Immunol 2006;118:434-40
4. Wilson DR, Lima MT. Sublingual immunotherapy for allergic rhinitis: systematic review and meta-analysis. Allergy 2005; 60:4-12
5. Calamita Z, Saconato H, Pelá AB et al. Efficacy of sublingual immunotherapy in asthma: systematic review of randomised-clinical trials using the Cochrane Collaboration method. Allergy 2006;61:1162-72
6. Marogna M, Massolo A. The type of sensitizing allergen can affect the evolution of respiratory allergy. Allergy 2006;61:1209-15
7. Canonica GW. Recommendation for standardization of clinical trials with allergen specific immunotherapy for respiratory allergy. A statement of a World Allergy Organization (WAO) task force. Allergy 2007;62:317-24
8. Valovirta E, Jacobsen L, Ljørring C. Clinical efficacy and safety of sublingual immunotherapy with tree pollen extract in children. Allergy 2006;61:1177-83
9. Asher MI, Keil U, Anderson HR, et al. International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. Eur Respir J, 1995;8:483-91
10. Durham S, Yang WH, Pedersen MR, et al. Sublingual immunetherapy with once-daily grass allergen tablets: a randomized controlled trial in seasonal allergic rhinoconjunctivitis. J Allergy Clin Immunol 2006;117:802-9
11. Penagos M, Compalati E, Tarantini F. Efficacy of sublingual immunotherapy in the treatment of allergic rhinitis in pediatric patients 3 to 18 years of age: a meta-analysis of randomized, placebo-controlled, double-blind trials. Ann Allergy Asthma Immunol 2006;97:141-8
12. Dahl R, Kapp A, Colombo G, et al. Efficacy and safety of sublingual immunotherapy with grass allergen tablets for seasonal allergic rhinoconjunctivitis. J Allergy Clin Immunol 2006;118: 434-40
13. Jadad A, Rennie D. The randomized controlled trial gets a middle-aged checkup. JAMA 1998;279:319-20
14. Sackett DL, Gent M. Controversy in counting and attributing events in clinical trials. N Eng J Med 1979;301:1410-12
15. Rothwell PM. External validity of randomised controlled trials: to whom do the results of this trial apply?' Lancet 2005;365: 82-93
16. Durham SR, Walker SM, Varga EM, et al. Long-term clinical efficacy of grass-pollen immunotherapy. N Engl J Med 1999; 341:468
17. Stephenson BJ. Is this patient taking their medication? JAMA 1993;269:2779-81
18. Concato J. Randomized controlled trials, observational studies and the hierarchy of research design. N Eng J Med 2000;342: 1887-92
19. Feinstein AR. The Architecture of Clinical Research. Philadelphia, PA: WB Saunders, 1985
20. Laupacis A. Observational studies of treatment effectiveness: some cautions. Ann Intern Med 2004;140:923-4
21. Passalacqua G, Guerra L. Efficacy and safety of sublingual immunotherapy. Ann Asthma Allergy Immunol 2004;93:3-12