Stimulation of fetal hypothalamus induces uterine contractions in pregnant rats at term

Biology of Reproduction

Volumn 79, Issue 4, 2008, Pages 633-637

  Endoh, Hisashi ^a   Fujioka, Takashi ^a   Endo, Hideki ^a   Inazuka, Yukiko ^a   Furukawa, Susumu ^a   Nakamura, Shoji ^a  

^a YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Embryo; Hypothalamus; Oxytocin; Pregnancy; Uterus

Indexed keywords

ARGIPRESTOCIN; OXYTOCIN; OXYTOCIN RECEPTOR; URETHAN;

ANIMAL EXPERIMENT; ARTICLE; BRAIN DEPTH STIMULATION; CONTROLLED STUDY; ELECTROSTIMULATION; FEMALE; FETOPLACENTAL UNIT; FIRST TRIMESTER PREGNANCY; HYPOTHALAMUS; MALE; MYOMETRIUM; NONHUMAN; PRIORITY JOURNAL; RAT; UMBILICAL CORD; UTERUS CONTRACTION;

ANIMALS; ELECTRIC STIMULATION; FEMALE; FETUS; HYPOTHALAMUS; MODELS, BIOLOGICAL; OXYTOCIN; PARTURITION; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; TERM BIRTH; UTERINE CONTRACTION;

RATTUS;

EID: 53349153331     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.108.069120     Document Type: Article

References (18)

1. Russell JA, Leng G. Sex, parturition, and motherhood without oxytocin? J Endocrinol 1998; 157:343-359.
2. Chard T, Hudson CN, Edwards CRW, Boyd NRH. Release of oxytocin and vasopressin by the human fetus during labor. Nature 1971; 234:352-353.
3. Chard T. Fetal and maternal oxytocin in human parturition. Am J Perinatol 1989; 6:145-152.
4. Boer K, Dogterom J, Pronker HF. Pituitary content of oxytocin, vasopressin, and alpha-melanocyte-stimulating hormone in the fetus of the rat during labor. J Endocrinol 1980; 86:221-229.
5. Nakamura S, Sakaguchi T. Development and plasticity of the locus coeruleus: a review of recent physiological and pharmacological experimentation. Prog Neurobiol (Oxford) 1990; 34:505-526.
6. Antonijevic IA, Douglas AJ, Dye S, Bicknell RJ, Leng G, Russell JA. Oxytocin antagonists delay the initiation of parturition and prolong its active phase in rats. J Endocrinol 1995; 145:97-103.
7. Kobayashi M, Akahane M, Minami K, Moro M, Ajisawa Y, Inoue Y, Kawarabayashi T. Role of oxytocin in the initiation of term and preterm labor in rats: changes in oxytocin receptor density and plasma oxytocin concentration and the effect of an oxytocin antagonist, L-366,509. Am J Obstet Gynecol 1999; 180:621-627.
8. Schellenberg JC. The effect of oxytocin receptor blockade on parturition in guinea pigs. J Clin Invest 1995; 95:13-19.
9. 2-adrenoceptor blockade on myometrial oxytocin receptors in parturient rats. Biol Reprod 1999; 60:322-329.
10. Young WSI, Shepard E, Amico J, Henninghausen L, Wagner K-U, LaMarca ME, McKinney A, Ginns E. Deficiency in mouse oxytocin prevents milk ejection, but not fertility or parturition. J Neuroendocrinol 1996; 8:847-853.
11. Nishimori K, Young LJ, Guo Q, Wang Z, Insel TR, Matzuk MM. Oxytocin is required for nursing but is not essential for parturition or reproductive behavior. Proc Natl Acad Sci U S A 1996; 93:11699-11704.
12. Muglia LJ. Genetic analysis of fetal development and parturition control in the mouse. Pediatr Res 2000; 47:437-443.
13. Otsuki Y, Tanizawa O, Yamaji K, Fujita M, Kurachi K. Feto-maternal plasma oxytocin levels in normal and anencephalic pregnancies. Acta Obstet Gynecol Scand 1983; 62:235-237.
14. Takayanagi Y, Yoshida M, Bielsky IF, Ross HE, Kawamata M, Onaka T, Yanagisawa T, Kimura T, Matzuk MM, Young LJ, Nishimori K. Pervasive social, but normal parturition, in oxytocin receptor-deficient mice. Proc Natl Acad Sci U S A 2005; 102:16096-16101.
15. Imamura T, Luedke CE, Vogt SK, Muglia LJ. Oxytocin modulates the onset of murine parturition by competing ovarian and uterine effects. Am J Physiol Regul Integr Comp Physiol 2000; 279:R1061-R1067.
16. Gross GA, Imamura T, Luedke C, Vogt SK, Olson LM, Nelson DM, Sadovsky Y, Muglia LJ. Opposing actions of prostaglandins and oxytocin determine the onset of murine labor. Proc Natl Acad Sci U S A 1998; 95:11875-11879.
17. Liggins GC, Kennedy PC, Holm LW. Failure of initiation of parturition after electrocoagulation of the pituitary of the fetal lamb. Am J Obstet Gynecol 1967; 98:1080-1086.
18. Casey ML, Winkel CA, Porter JC, MacDonald PC. Endocrine regulation of the initiation and maintenance of parturition. Clin Perinatol 1983; 10:709-721.