Immune response following miltefosine therapy in a patient with post-kala-azar dermal leishmaniasis

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 102, Issue 11, 2008, Pages 1160-1162

  Ansari, Nasim Akhtar ^a   Ramesh, V ^b   Salotra, Poonam ^a  

^a SAFDARJUNG HOSPITAL CAMPUS   (India)

^b SAFDARJUNG HOSPITAL   (India)

Author keywords

Immune response; India; Leishmania; Miltefosine; Post kala azar dermal leishmaniasis; Rheumatoid arthritis

Indexed keywords

CD40 ANTIGEN; CLOFAZIMINE; GAMMA INTERFERON; HYDROXYCHLOROQUINE; INTERLEUKIN 10; LEPROSTATIC AGENT; MILTEFOSINE; RHEUMATOID FACTOR; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ARTHRALGIA; ARTICLE; CASE REPORT; CONTROLLED STUDY; FOLLOW UP; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOPIGMENTATION; IMMUNE RESPONSE; INDIA; KNEE PAIN; LABORATORY TEST; LEISHMANIA DONOVANI; LEPROSY; MALE; NONHUMAN; PAPULE; PARASITE IDENTIFICATION; PARASITE ISOLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SKIN BIOPSY; SKIN DISCOLORATION; SKIN EXAMINATION; SKIN LEISHMANIASIS; SKIN MANIFESTATION; TREATMENT DURATION; TREATMENT OUTCOME;

ADOLESCENT; ANIMALS; ANTIPROTOZOAL AGENTS; CLOFAZIMINE; DIAGNOSIS, DIFFERENTIAL; HUMANS; HYPOPIGMENTATION; LEISHMANIA DONOVANI; LEISHMANIASIS, CUTANEOUS; LEISHMANIASIS, VISCERAL; LEPROSTATIC AGENTS; MALE; MEDICATION ERRORS; PHOSPHORYLCHOLINE; POLYMERASE CHAIN REACTION;

NASO HEXACANTHUS;

EID: 53349143382     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trstmh.2008.05.015     Document Type: Article

References (5)

1. Ansari N.A., Ramesh V., and Salotra P. IFN-γ, TNF-α, IL-6 and IFN-γR1 are the major immunological determinants associated with post-kala azar dermal leishmaniasis. J. Infect. Dis. 194 (2006) 958-965
2. Belay A.D., Asafa Y., Mesure J., and Davidson R.N. Successful miltefosine treatment of post-kala-azar dermal leishmaniasis occurring during antiretroviral therapy. Ann. Trop. Med. Parasitol. 100 (2006) 223-227
3. Murray H.W., and Delph-Etienne S. Visceral leishmanicidal activity of hexadecylphosphocholine (miltefosine) in mice deficient in T cells and activated macrophage microbicidal mechanisms. J. Infect. Dis. 181 (2000) 795-799
4. Ramesh V., Ansari N.A., Jain R.K., and Salotra P. Oral miltefosine in the treatment of post-kala-azar dermal leishmaniasis. Clin. Exp. Dermatol. 33 (2008) 103-105
5. Saha S., Mondal S., Ravindran R., Bhowmick S., Modak D., Mallick S., Rahman M., Kar S., Goswami R., Guha S.K., Pramanik N., Saha B., and Ali N. IL-10- and TGF-beta-mediated susceptibility in kala-azar and post-kala-azar dermal leishmaniasis: the significance of amphotericin B in the control of Leishmania donovani infection in India. J. Immunol. 179 (2007) 5592-5603