-
1
-
-
0035799654
-
Microarrays of cells expressing defined cDNAs
-
10.1038/35075114 11333987
-
Ziauddin J Sabatini DM Microarrays of cells expressing defined cDNAs Nature 2001, 411(6833):107-110. 10.1038/35075114 11333987
-
(2001)
Nature
, vol.411
, Issue.6833
, pp. 107-110
-
-
Ziauddin, J.1
Sabatini, D.M.2
-
2
-
-
31744445957
-
Microarrays of lentiviruses for gene function screens in immortalized and primary cells
-
10.1038/nmeth848 16432521
-
Bailey SN Ali SM Carpenter AE Higgins CO Sabatini DM Microarrays of lentiviruses for gene function screens in immortalized and primary cells Nat Methods 2006, 3(2):117-122. 10.1038/nmeth848 16432521
-
(2006)
Nat Methods
, vol.3
, Issue.2
, pp. 117-122
-
-
Bailey, S.N.1
Ali, S.M.2
Carpenter, A.E.3
Higgins, C.O.4
Sabatini, D.M.5
-
3
-
-
33846865789
-
Retroviral microarray-based platform on nanostructured TiO2 for functional genomics and drug discovery
-
10.1016/j.biomaterials.2006.12.026 17276506
-
Carbone R Giorgetti L Zanardi A Marangi I Chierici E Bongiorno G Fiorentini F Faretta M Piseri P Pelicci PG et al.: Retroviral microarray-based platform on nanostructured TiO2 for functional genomics and drug discovery Biomaterials 2007, 28(13):2244-2253. 10.1016/ j.biomaterials.2006.12.026 17276506
-
(2007)
Biomaterials
, vol.28
, Issue.13
, pp. 2244-2253
-
-
Carbone, R.1
Giorgetti, L.2
Zanardi, A.3
Marangi, I.4
Chierici, E.5
Bongiorno, G.6
Fiorentini, F.7
Faretta, M.8
Piseri, P.9
Pelicci, P.G.10
-
4
-
-
0036842503
-
Arrayed adenoviral expression libraries for functional screening
-
10.1038/nbt746 12355097
-
Michiels F van EsH van Rompaey L Merchiers P Francken B Pittois K Schueren van der J Brys R Vandersmissen J Beirinckx F et al.: Arrayed adenoviral expression libraries for functional screening Nat Biotechnol 2002, 20(11):1154-1157. 10.1038/nbt746 12355097
-
(2002)
Nat Biotechnol
, vol.20
, Issue.11
, pp. 1154-1157
-
-
Michiels, F.1
Van, Es.H.2
van Rompaey, L.3
Merchiers, P.4
Francken, B.5
Pittois, K.6
Schueren, J.7
Brys, R.8
Vandersmissen, J.9
Beirinckx, F.10
-
5
-
-
24344500241
-
Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing
-
10.1089/108729003321629638 12804036
-
Harborth J Elbashir SM Vandenburgh K Manninga H Scaringe SA Weber K Tuschl T Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing Antisense Nucleic Acid Drug Dev 2003, 13(2):83-105. 10.1089/ 108729003321629638 12804036
-
(2003)
Antisense Nucleic Acid Drug Dev
, vol.13
, Issue.2
, pp. 83-105
-
-
Harborth, J.1
Elbashir, S.M.2
Vandenburgh, K.3
Manninga, H.4
Scaringe, S.A.5
Weber, K.6
Tuschl, T.7
-
6
-
-
0034185302
-
BTK mediated apoptosis, a possible mechanism for failure to generate high titer retroviral producer clones
-
10.1002/(SICI)1521-2254(200005/06)2:3<204::AID-JGM104>3.0.CO;2-5 10894266
-
Islam TC Branden LJ Kohn DB Islam KB Smith CI BTK mediated apoptosis, a possible mechanism for failure to generate high titer retroviral producer clones J Gene Med 2000, 2(3):204-209. 10.1002/ (SICI)1521-2254(200005/06)2:3<204::AID-JGM104>3.0.CO;2-5 10894266
-
(2000)
J Gene Med
, vol.2
, Issue.3
, pp. 204-209
-
-
Islam, T.C.1
Branden, L.J.2
Kohn, D.B.3
Islam, K.B.4
Smith, C.I.5
-
7
-
-
0034508241
-
The cellular phenotype conditions Btk for cell survival or apoptosis signaling
-
10.1034/j.1600-065X.2000.17811.x 11213806
-
Islam TC Smith CI The cellular phenotype conditions Btk for cell survival or apoptosis signaling Immunol Rev 2000, 178:49-63. 10.1034/ j.1600-065X.2000.17811.x 11213806
-
(2000)
Immunol Rev
, vol.178
, pp. 49-63
-
-
Islam, T.C.1
Smith, C.I.2
-
8
-
-
0031708849
-
Bruton's tyrosine kinase (BTK) as a dual-function regulator of apoptosis
-
10.1016/S0006-2952(98)00122-1 9751072
-
Uckun FM Bruton's tyrosine kinase (BTK) as a dual-function regulator of apoptosis Biochem Pharmacol 1998, 56(6):683-691. 10.1016/ S0006-2952(98)00122-1 9751072
-
(1998)
Biochem Pharmacol
, vol.56
, Issue.6
, pp. 683-691
-
-
Uckun, F.M.1
-
9
-
-
24644467226
-
p38 MAP kinase plays a role in G2 checkpoint activation and inhibits apoptosis of human B cell lymphoma cells treated with etoposide
-
10.1007/s10495-005-3372-z 16151644
-
Kurosu T Takahashi Y Fukuda T Koyama T Miki T Miura O p38 MAP kinase plays a role in G2 checkpoint activation and inhibits apoptosis of human B cell lymphoma cells treated with etoposide Apoptosis 2005, 10(5):1111-1120. 10.1007/s10495-005-3372-z 16151644
-
(2005)
Apoptosis
, vol.10
, Issue.5
, pp. 1111-1120
-
-
Kurosu, T.1
Takahashi, Y.2
Fukuda, T.3
Koyama, T.4
Miki, T.5
Miura, O.6
-
10
-
-
33744494283
-
Inhibition of p38alpha MAPK enhances proteasome inhibitor-induced apoptosis of myeloma cells by modulating Hsp27, Bcl-X(L), Mcl-1 and p53 levels in vitro and inhibits tumor growth in vivo
-
10.1038/sj.leu.2404200 16617327
-
Navas TA Nguyen AN Hideshima T Reddy M Ma JY Haghnazari E Henson M Stebbins EG Kerr I O'Young G et al.: Inhibition of p38alpha MAPK enhances proteasome inhibitor-induced apoptosis of myeloma cells by modulating Hsp27, Bcl-X(L), Mcl-1 and p53 levels in vitro and inhibits tumor growth in vivo Leukemia 2006, 20(6):1017-1027. 10.1038/ sj.leu.2404200 16617327
-
(2006)
Leukemia
, vol.20
, Issue.6
, pp. 1017-1027
-
-
Navas, T.A.1
Nguyen, A.N.2
Hideshima, T.3
Reddy, M.4
Ma, J.Y.5
Haghnazari, E.6
Henson, M.7
Stebbins, E.G.8
Kerr, I.9
O'Young, G.10
-
11
-
-
34548724059
-
Epidermal growth factor receptor signaling modulates apoptosis via p38alpha MAPK-dependent activation of Bax in intestinal epithelial cells
-
10.1152/ajpgi.00182.2007 17615176
-
Sheng G Guo J Warner BW Epidermal growth factor receptor signaling modulates apoptosis via p38alpha MAPK-dependent activation of Bax in intestinal epithelial cells Am J Physiol Gastrointest Liver Physiol 2007, 293(3):G599-606. 10.1152/ajpgi.00182.2007 17615176
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.293
, Issue.3
-
-
Sheng, G.1
Guo, J.2
Warner, B.W.3
-
12
-
-
33749503799
-
Combined depletion of cell cycle and transcriptional cyclin-dependent kinase activities induces apoptosis in cancer cells
-
10.1158/0008-5472.CAN-06-1758 16982772
-
Cai D Latham VM Jr Zhang X Shapiro GI Combined depletion of cell cycle and transcriptional cyclin-dependent kinase activities induces apoptosis in cancer cells Cancer Res 2006, 66(18):9270-9280. 10.1158/ 0008-5472.CAN-06-1758 16982772
-
(2006)
Cancer Res
, vol.66
, Issue.18
, pp. 9270-9280
-
-
Cai, D.1
Latham Jr., V.M.2
Zhang, X.3
Shapiro, G.I.4
-
13
-
-
4544233360
-
Measurement of changes in apoptosis and cell cycle regulatory kinase Cdk2
-
15105561
-
Gil-Gomez G Measurement of changes in apoptosis and cell cycle regulatory kinase Cdk2 Methods Mol Biol 2004, 282:131-144. 15105561
-
(2004)
Methods Mol Biol
, vol.282
, pp. 131-144
-
-
Gil-Gomez, G.1
-
14
-
-
0035881591
-
A novel cdk2-selective inhibitor, SU induces apoptosis in colon carcinoma cells
-
11507069
-
Lane ME Yu B Rice A Lipson KE Liang C Sun L Tang C McMahon G Pestell RG Wadler S A novel cdk2-selective inhibitor, SU induces apoptosis in colon carcinoma cells Cancer Res 2001, 61(16):6170-6177. 11507069
-
(2001)
Cancer Res
, vol.61
, Issue.16
, pp. 6170-6177
-
-
Lane, M.E.1
Yu, B.2
Rice, A.3
Lipson, K.E.4
Liang, C.5
Sun, L.6
Tang, C.7
McMahon, G.8
Pestell, R.G.9
Wadler, S.10
-
15
-
-
9144255423
-
Protein kinase PKN1 associates with TRAF2 and is involved in TRAF2-NF-kappaB signaling pathway
-
10.1016/j.bbrc.2003.12.148 14741690
-
Gotoh Y Oishi K Shibata H Yamagiwa A Isagawa T Nishimura T Goyama E Takahashi M Mukai H Ono Y Protein kinase PKN1 associates with TRAF2 and is involved in TRAF2-NF-kappaB signaling pathway Biochem Biophys Res Commun 2004, 314(3):688-694. 10.1016/j.bbrc.2003.12.148 14741690
-
(2004)
Biochem Biophys Res Commun
, vol.314
, Issue.3
, pp. 688-694
-
-
Gotoh, Y.1
Oishi, K.2
Shibata, H.3
Yamagiwa, A.4
Isagawa, T.5
Nishimura, T.6
Goyama, E.7
Takahashi, M.8
Mukai, H.9
Ono, Y.10
-
16
-
-
33646573938
-
Protein kinases controlling the onset of mitosis
-
10.1007/s00018-005-5515-3 16465440
-
Ferrari S Protein kinases controlling the onset of mitosis Cell Mol Life Sci 2006, 63(7-8):781-795. 10.1007/s00018-005-5515-3 16465440
-
(2006)
Cell Mol Life Sci
, vol.63
, Issue.7-8
, pp. 781-795
-
-
Ferrari, S.1
-
17
-
-
33646839443
-
Nek2 kinase in chromosome instability and cancer
-
10.1016/j.canlet.2005.06.017 16084011
-
Hayward DG Fry AM Nek2 kinase in chromosome instability and cancer Cancer Lett 2006, 237(2):155-166. 10.1016/j.canlet.2005.06.017 16084011
-
(2006)
Cancer Lett
, vol.237
, Issue.2
, pp. 155-166
-
-
Hayward, D.G.1
Fry, A.M.2
-
18
-
-
40549126830
-
Mitotic regulation by NIMA-related kinases
-
2018689 17727698 10.1186/1747-1028-2-25
-
O'Regan L Blot J Fry AM Mitotic regulation by NIMA-related kinases Cell Div 2007, 2:25. 2018689 17727698 10.1186/1747-1028-2-25
-
(2007)
Cell Div
, vol.2
, pp. 25
-
-
O'Regan, L.1
Blot, J.2
Fry, A.M.3
-
19
-
-
34249308194
-
PBK/TOPK promotes tumour cell proliferation through p38 MAPK activity and regulation of the DNA damage response
-
10.1038/sj.onc.1210142 17160018
-
Ayllon V O'Connor R PBK/TOPK promotes tumour cell proliferation through p38 MAPK activity and regulation of the DNA damage response Oncogene 2007, 26(24):3451-3461. 10.1038/sj.onc.1210142 17160018
-
(2007)
Oncogene
, vol.26
, Issue.24
, pp. 3451-3461
-
-
Ayllon, V.1
O'Connor, R.2
-
20
-
-
34248146665
-
Attenuation of DNA damage checkpoint by PBK, a novel mitotic kinase, involves protein-protein interaction with tumor suppressor p53
-
10.1016/j.bbrc.2007.04.125 17482142
-
Nandi AK Ford T Fleksher D Neuman B Rapoport AP Attenuation of DNA damage checkpoint by PBK, a novel mitotic kinase, involves protein-protein interaction with tumor suppressor p53 Biochem Biophys Res Commun 2007, 358(1):181-188. 10.1016/j.bbrc.2007.04.125 17482142
-
(2007)
Biochem Biophys Res Commun
, vol.358
, Issue.1
, pp. 181-188
-
-
Nandi, A.K.1
Ford, T.2
Fleksher, D.3
Neuman, B.4
Rapoport, A.P.5
-
21
-
-
0036731975
-
TrkA as a life and death receptor: Receptor dose as a mediator of function
-
12208732
-
Yan C Liang Y Nylander KD Schor NF TrkA as a life and death receptor: receptor dose as a mediator of function Cancer Res 2002, 62(17):4867-4875. 12208732
-
(2002)
Cancer Res
, vol.62
, Issue.17
, pp. 4867-4875
-
-
Yan, C.1
Liang, Y.2
Nylander, K.D.3
Schor, N.F.4
-
22
-
-
0033003760
-
A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays
-
10.1177/108705719900400206 10838414
-
Zhang JH Chung TD Oldenburg KR A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays J Biomol Screen 1999, 4(2):67-73. 10.1177/108705719900400206 10838414
-
(1999)
J Biomol Screen
, vol.4
, Issue.2
, pp. 67-73
-
-
Zhang, J.H.1
Chung, T.D.2
Oldenburg, K.R.3
-
23
-
-
33646033137
-
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen
-
10.1016/j.cell.2006.01.040 16564017
-
Moffat J Grueneberg DA Yang X Kim SY Kloepfer AM Hinkle G Piqani B Eisenhaure TM Luo B Grenier JK et al.: A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen Cell 2006, 124(6):1283-1298. 10.1016/j.cell.2006.01.040 16564017
-
(2006)
Cell
, vol.124
, Issue.6
, pp. 1283-1298
-
-
Moffat, J.1
Grueneberg, D.A.2
Yang, X.3
Kim, S.Y.4
Kloepfer, A.M.5
Hinkle, G.6
Piqani, B.7
Eisenhaure, T.M.8
Luo, B.9
Grenier, J.K.10
-
24
-
-
33747794587
-
Genome-scale loss-of-function screening with a lentiviral RNAi library
-
10.1038/nmeth924 16929317
-
Root DE Hacohen N Hahn WC Lander ES Sabatini DM Genome-scale loss-of-function screening with a lentiviral RNAi library Nat Methods 2006, 3(9):715-719. 10.1038/nmeth924 16929317
-
(2006)
Nat Methods
, vol.3
, Issue.9
, pp. 715-719
-
-
Root, D.E.1
Hacohen, N.2
Hahn, W.C.3
Lander, E.S.4
Sabatini, D.M.5
-
25
-
-
41149091256
-
Transient transfection methods for preparation of high-titer retroviral supernatants
-
Chapter 9 Unit9.11 Unit9 11. 18265279
-
Pear W Transient transfection methods for preparation of high-titer retroviral supernatants Curr Protoc Mol Biol 2001, Chapter 9 Unit9.11 Unit9 11. 18265279
-
(2001)
Curr Protoc Mol Biol
-
-
Pear, W.1
-
26
-
-
10744221455
-
Adenoviral vectors expressing siRNAs for discovery and validation of gene function
-
403715 12975310 10.1101/gr.1332603
-
Arts GJ Langemeijer E Tissingh R Ma L Pavliska H Dokic K Dooijes R Mesic E Clasen R Michiels F et al.: Adenoviral vectors expressing siRNAs for discovery and validation of gene function Genome Res 2003, 13(10):2325-2332. 403715 12975310 10.1101/gr.1332603
-
(2003)
Genome Res
, vol.13
, Issue.10
, pp. 2325-2332
-
-
Arts, G.J.1
Langemeijer, E.2
Tissingh, R.3
Ma, L.4
Pavliska, H.5
Dokic, K.6
Dooijes, R.7
Mesic, E.8
Clasen, R.9
Michiels, F.10
-
27
-
-
18244403744
-
Involvement of protein kinase PKN1 in G2/M delay caused by arsenite
-
10.1002/mc.20087 15791647
-
Isagawa T Takahashi M Kato T Jr Mukai H Ono Y Involvement of protein kinase PKN1 in G2/M delay caused by arsenite Mol Carcinog 2005, 43(1):1-12. 10.1002/mc.20087 15791647
-
(2005)
Mol Carcinog
, vol.43
, Issue.1
, pp. 1-12
-
-
Isagawa, T.1
Takahashi, M.2
Kato Jr., T.3
Mukai, H.4
Ono, Y.5
-
28
-
-
34248597065
-
Differential regulation and properties of MAPKs
-
10.1038/sj.onc.1210392 17496909
-
Raman M Chen W Cobb MH Differential regulation and properties of MAPKs Oncogene 2007, 26(22):3100-3112. 10.1038/sj.onc.1210392 17496909
-
(2007)
Oncogene
, vol.26
, Issue.22
, pp. 3100-3112
-
-
Raman, M.1
Chen, W.2
Cobb, M.H.3
-
29
-
-
2442593499
-
Therapeutic potential of inhibiting Bruton's tyrosine kinase, (BTK)
-
10.2174/1381612043384475 15180538
-
Vassilev AO Uckun FM Therapeutic potential of inhibiting Bruton's tyrosine kinase, (BTK) Curr Pharm Des 2004, 10(15):1757-1766. 10.2174/ 1381612043384475 15180538
-
(2004)
Curr Pharm Des
, vol.10
, Issue.15
, pp. 1757-1766
-
-
Vassilev, A.O.1
Uckun, F.M.2
-
30
-
-
35248864084
-
Comprehensive expression profiling of tumor cell lines identifies molecular signatures of melanoma progression
-
1895889 17611626 10.1371/journal.pone.0000594
-
Ryu B Kim DS Deluca AM Alani RM Comprehensive expression profiling of tumor cell lines identifies molecular signatures of melanoma progression PLoS ONE 2007, 2(7):e594. 1895889 17611626 10.1371/journal.pone.0000594
-
(2007)
PLoS ONE
, vol.2
, Issue.7
-
-
Ryu, B.1
Kim, D.S.2
Deluca, A.M.3
Alani, R.M.4
-
31
-
-
3242890471
-
siRNA Selection Server: An automated siRNA oligonucleotide prediction server
-
(Web Server) 441504 15215365 10.1093/nar/gkh366
-
Yuan B Latek R Hossbach M Tuschl T Lewitter F siRNA Selection Server: An automated siRNA oligonucleotide prediction server Nucleic Acids Res 2004, 32(Web Server):W130-134. 441504 15215365 10.1093/nar/gkh366
-
(2004)
Nucleic Acids Res
-
-
Yuan, B.1
Latek, R.2
Hossbach, M.3
Tuschl, T.4
Lewitter, F.5
-
32
-
-
3242877996
-
Sfold web server for statistical folding and rational design of nucleic acids
-
(Web Server) 441587 15215366 10.1093/nar/gkh449
-
Ding Y Chan CY Lawrence CE Sfold web server for statistical folding and rational design of nucleic acids Nucleic Acids Res 2004, 32(Web Server):W135-141. 441587 15215366 10.1093/nar/gkh449
-
(2004)
Nucleic Acids Res
-
-
Ding, Y.1
Chan, C.Y.2
Lawrence, C.E.3
-
33
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
10.1126/science.1068999 11910072
-
Brummelkamp TR Bernards R Agami R A system for stable expression of short interfering RNAs in mammalian cells Science 2002, 296(5567):550-553. 10.1126/science.1068999 11910072
-
(2002)
Science
, vol.296
, Issue.5567
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
34
-
-
0037089589
-
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
-
152352 11959843 10.1101/gad.981002
-
Paddison PJ Caudy AA Bernstein E Hannon GJ Conklin DS Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells Genes Dev 2002, 16(8):948-958. 152352 11959843 10.1101/gad.981002
-
(2002)
Genes Dev
, vol.16
, Issue.8
, pp. 948-958
-
-
Paddison, P.J.1
Caudy, A.A.2
Bernstein, E.3
Hannon, G.J.4
Conklin, D.S.5
-
35
-
-
0032478271
-
A simplified system for generating recombinant adenoviruses
-
19394 9482916 10.1073/pnas.95.5.2509
-
He TC Zhou S da Costa LT Yu J Kinzler KW Vogelstein B A simplified system for generating recombinant adenoviruses Proc Natl Acad Sci USA 1998, 95(5):2509-2514. 19394 9482916 10.1073/pnas.95.5.2509
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.5
, pp. 2509-2514
-
-
He, T.C.1
Zhou, S.2
da Costa, L.T.3
Yu, J.4
Kinzler, K.W.5
Vogelstein, B.6
-
36
-
-
0032834927
-
Adenovirus vectors for gene delivery
-
10.1016/S0958-1669(99)00007-5 10508634
-
Benihoud K Yeh P Perricaudet M Adenovirus vectors for gene delivery Curr Opin Biotechnol 1999, 10(5):440-447. 10.1016/S0958-1669(99)00007-5 10508634
-
(1999)
Curr Opin Biotechnol
, vol.10
, Issue.5
, pp. 440-447
-
-
Benihoud, K.1
Yeh, P.2
Perricaudet, M.3
-
37
-
-
33646839924
-
Cell adhesion profiling using extracellular matrix protein microarrays
-
16629399
-
Kuschel C Steuer H Maurer AN Kanzok B Stoop R Angres B Cell adhesion profiling using extracellular matrix protein microarrays Biotechniques 2006, 40(4):523-531. 16629399
-
(2006)
Biotechniques
, vol.40
, Issue.4
, pp. 523-531
-
-
Kuschel, C.1
Steuer, H.2
Maurer, A.N.3
Kanzok, B.4
Stoop, R.5
Angres, B.6
-
38
-
-
35148845555
-
A novel strategy for mammalian cell surface glycome profiling using lectin microarray
-
10.1093/glycob/cwm084 17693441
-
Tateno H Uchiyama N Kuno A Togayachi A Sato T Narimatsu H Hirabayashi J A novel strategy for mammalian cell surface glycome profiling using lectin microarray Glycobiology 2007, 17(10):1138-1146. 10.1093/glycob/ cwm084 17693441
-
(2007)
Glycobiology
, vol.17
, Issue.10
, pp. 1138-1146
-
-
Tateno, H.1
Uchiyama, N.2
Kuno, A.3
Togayachi, A.4
Sato, T.5
Narimatsu, H.6
Hirabayashi, J.7
|