A study to sustain the hypothesis of the multiple genesis of oligoasthenoteratospermia in human idiopathic infertile males

Biology of Reproduction

Volumn 79, Issue 4, 2008, Pages 667-673

  Cavallini, Giorgio ^a,d   Crippa, Andor ^a   Magli, Maria Cristina ^a   Cavallini, Nicola ^b   Ferraretti, Anna Pia ^c   Gianaroli, Luca ^c  

^a Laboratory of Assisted Reproduction   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c SISMER   (Italy)

^d NONE   (Italy)

Author keywords

Gamete biology; Gametogenesis; Idiopathic oligoasthenoteratospermia; Male infertility; Sperm

Indexed keywords

ADULT; ANEUPLOIDY; ARTICLE; AZOOSPERMIA; CHROMOSOME 13; CHROMOSOME 15; CHROMOSOME 16; CHROMOSOME 17; CHROMOSOME 18; CHROMOSOME 21; CHROMOSOME 22; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; GAMETOGENESIS; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; OLIGOASTHENOTERATOSPERMIA; PRIORITY JOURNAL; SPERMATOZOON DENSITY; SPERMATOZOON MOTILITY; TESTIS DISEASE; X CHROMOSOME; Y CHROMOSOME;

ADULT; ANEUPLOIDY; ASTHENOZOOSPERMIA; AZOOSPERMIA; CYTOGENETIC ANALYSIS; GENES, DEVELOPMENTAL; HUMANS; INFERTILITY, MALE; MALE; OLIGOSPERMIA; SPERM COUNT; SPERM MOTILITY;

EID: 53349099255     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.107.067330     Document Type: Article

References (67)

1. Cavallini G. Male idiopathic oligo-astheno-terato-sperospermia. Asian J Androl 2006; 8:143-157.
2. Comhaire FH, Mahmoud AM, Depuydt CE, Zalata AA, Christophe AB. Mechanisms and effects of male genital tract infection on sperm quality and fertilizing potential: the andrologist's viewpoint. Hum Reprod Update 1999; 5:393-398.
3. Hikim AP, Wang C, Lue Y, Johnson L, Wang XH, Swerdloff RS. Spontaneous germ cell apoptosis in humans: evidence for ethnic differences in the susceptibility of germ cells to programmed cell death. J Clin Endocrinol Metab 1998; 83:152-156.
4. Francavilla S, D'Abrizio P, Cordeschi G, Pelliccione F, Necozione S, Ulisse S, Properzi G, Fancavilla F. Fas expression correlates with human germ cell degeneration in meiotic and post-meiotic arrest of spermatogenesis. Mol Hum Reprod 2002; 8:213-220.
5. Amral A, Ramlho Santos J, St. John JC. The expression of polymerase gamma on a mitochondrial transcription factor A and the regulation of mitochondrial DNA content in mature human sperm. Hum Reprod 2007; 22:1585-1596.
6. St. John JC, Bowles EJ, Amaral A. Sperm mitochondria and fertilization. Soc Reprod Fertil Suppl 2007; 65:399-416.
7. Silber SJ. Evaluation and treatment of male infertility. Clin Obstet Gynecol 2000; 43:854-888.
8. Lewis SEM. Is sperm evaluation useful in predicting human fertility? Reproduction 2007; 134:31-40.
9. World Health Organization. 1999 WHO Laboratory Manual for the Examination of Human Semen and Semen-Cervical Mucus Interaction, 4th ed. Cambridge, UK: Cambridge University Press; 1999.
10. Muller CH. Rationale, interpretation, validation and uses of sperm function tests. J Androl 2000; 21:10-30.
11. Martin RH, Greene C, Rademaker A, Ko E, Chernos J. Analysis of aneuploidy in spermatozoa from testicular biopsies from men with non-obstructive azoospermia. J Androl 2003; 24:100-103.
12. Martin MH, Rademaker AW, Greene C, Ko E, Hoang T, Barclay L, Chernos J. A comparison of frequency of sperm chromosome abnormalities in men with mild, moderate or severe oligozoospermia. Biol Reprod 2003; 69:535-539.
13. Carrel DT. The clinical implementation of sperm chromosome aneuploidy testing: pitfalls and promises. J Androl 2008; 29:124-133.
14. Gianaroli L, Magli MC, Cavallini G, Crippa A, Nadalini M, Bernardini L, Menchini Fabris GF, Voliani S, Ferraretti AP. Frequency of aneuploidy in sperm from patients with extremely severe male factor infertility. Human Reprod 2005; 20:2140-2152.
15. Cavallini G, Ferraretti AP, Gianaroli L, Biagiotti G, Vitali G. Cinnoxicam and L-carnitine treatment for idiopathic and varicocele associated oligoasthenospermia. J Androl 2004; 25:761-772.
16. Iwamoto T, Nozawa S, Yoshiike K, Hoshino T, Baba K, Matsuhita T, Tanaka SN, Naka M, Skakkebaek NE, Jorgensen N. Semen quality of 324 fertile men. Hum Reprod 2006; 21:760-765.
17. Biagiotti G, Cavallini G, Modenini F, Vitali G, Gianaroli L. Spermatogenesis and spectral echo-colour Doppler traces form the main testicular artery. BJU Int 2002; 90:903-908.
18. Gunalp S, Onculoglu C, Gurgan T, Kruger TF, Lombard C. A study of semen parameters with emphasis on sperm morphology in a fertile population: an attempt to develop clinical thresholds. Hum Reprod 2001; 16:110-114.
19. Ombelet W, Bosmans E, Janssen M, Cox A, Vlasselaer J, Gyselaers W, Vandeput H, Gielen J, Pollet H, Maes M, Steeno O, Kruger T. Semen perameters in a fertile versus subfertile population: a need for change the interpretation of semen testing. Hum Reprod 1997; 12:987-993.
20. Guzick DS, Overstreet JW, Factor-Litvak P, Brazil CK, Nakajima ST, Coutifaris C, Carson SA, Cisneros P, Steinkampf MP, Hill JA, Xu D, Vogel DL. Sperm morphology, motility and concentration in fertile and infertile men. N Eng J Med 2001; 345:1388-1393.
21. Kruger TF, Menkveld R, Stander FS, Lombard CJ, Van der Merwe JP, Van Zyl JA, Smith K. Sperm morphologic features as prognostic factor in vitro fertilization. Fertil Steril 1986; 46:1118-1123.
22. Menkveld R, Kotze TJ, Kruger TK. Relationship of human sperm morphology with other semen parameters as seen in different populations. Hum Reprod 1992; 7:96-97.
23. Ushijima C, Kumasako Y, Kihaile PE, Hirotsuru K, Utsunomiya T. Analysis of chromosomal abnormalities in human spermatozoa using multi-colour fluorescence in-situ hybridization. Hum Reprod 2000; 15:1107-1111.
24. Xia Y, Cheng S, Bian Q, Xu L, Collins M, Chang HC, Song L, Liu J, Wang S, Wang X. Genotoxic effects of carbaril exposed workers. Toxicol Sci 2005; 85:615-623.
25. Camussi A, Moller F, Ottaviano E, Gorla M. 1995. Metodi Statistici per la Sperimentazione Biologica, 2nd ed. Bologna, Italy: Zanichelli; 1995:274-407.
26. Goodman SN. Stopping at nothing? Some dilemmas of data monitoring in clinical trails. Ann Intern Med 2007; 146:882-887.
27. Bernardini L, Gianaroli L, Fortini D, Conte N, Magli MC, Cavani S, Gaggero G, Tindiglia C, Ragni N, Ventirini PL. Frequency of hyperhypoaploidy and diploidy in ejaculate, epidydimal and testicular germ cells of infertile patients. Hum Reprod 2000; 15:2165-2172.
28. Palermo GD, Colombero LT, Hariprashad J, Schlegel PN, Rosenvacks Z. Chromosome analysis of epididimal and testicular sperm in azooospermic patients. Hum Reprod 2002; 17:570-575.
29. Calogero AE, De Palma A, Grazioso C, Barone N, Romeo R, Rappazzo G, D'Agata R. Aneuploidy rate in spermatozoa of selected men with abnormal semen parameters. Hum Reprod 2001; 16:1172-1179.
30. Pang MG, Kim YJ, Lee SH, Kim CK. The high incidence of meiotic errors increases with decreased sperm count in sever male factor infertilities. Hum Reprod 2005; 20:1688-1694.
31. Hrsitova R, Ko E, Greene C, Rademaker A, Chernos J, Martin R. Chromosome abnormalities in sperm from infertile men with asthenoteratospermia. Biol Reprod 2002; 66:1781-1783.
32. Pang MG, Hoegerman SF, Cuticchia AJ, Moon SY, Doncel GF, Acosta AA, Kearns WG. Detection of aneuploidy for chromosomes 4,6,7,8,9,10,11,12,13,17,18, 21 X and Y by fluorescence in situ hibridation in spermatozoa from nine patients with oligoasthenoteratospermia undergoing intracitoplasmic sperm injection. Hum Reprod 1999; 14:1266-1273.
33. Tempest HG, Homa ST, Dalakiouridou M, Christopikou D, Wright D, Zhai XP, Griffin DK. The association between male infertility and sperm disomy: evidence for variation in disomy levels among individuals and a correlation between particular semen parameters and disomy of specific chromosome pairs. Reprod Biol Endocrinol 2004; 2:82-91.
34. Collodel G, Capitani S, Baccetti B, Pammolli A, Moretti E. Sperm aneuploidies and low progressive motility. Hum Reprod 2007; 22:1893-1898.
35. Collodel G, Moretti E. Morphologic and meiotic segregation in spermatozoa from men of proven fertility. J Androl 2008; 29:106-114.
36. Trisini AT, Singh NP, Duty SM, Hauser M. Relationship between human semen parameters and deoxyribonucleic acid damaged assessed by neutral comet assay. Fertil Steril 2004; 82:1623-1632.
37. Wyrobeck AJ, Eskenazi B, Young S, Arnheim N, Tieman Boege I, Jabs EW, Glaser RL, Pearson FS, Evenson D. Advancing age has differential effects on DNA damage, chromatin integrity, gene mutations and aneuploidies in sperm. Proc Natl Acad Sci U S A 2006; 103:9601-9606.
38. Chohan KR, Griffin JT, Lafromboise M, De Jonge CJ, Carrell DT. Comparison of chromatin assays for DNA fragmentation evaluation in human sperm. J Androl 2006; 27:53-59.
39. Erenpreiss J, Jepson K, Giwercman A, Tsarev I, Erenpreisa J, Spano M. Toluidine blue cytometry test for sperm DNA conformation: comparison with the flow cytometric sperm chromatin structure and TUNEL assays. Hum Reprod 2004; 19:2277-2282.
40. Kamischke A, Nieschlag E. Varicocele treatment in the light of evidence-based andrology. Hum Reprod Update 2001; 7:65-69.
41. Kruger TF, Coetzee K. The role of sperm morphology in assisted reproduction. Hum Reprod Update 1999; 5:172-178.
42. Van Waart J, Kruger TF, Lombard CJ, Ombelet W. Predictive value of normal sperm morphology in intrauterine insemination (IUI): a structured literature review. Hum Reprod Update 2001; 7:495-500.
43. Liu DY, Baker HWG. Evaluation and assessment of semen for IVF/ICSI. Asian J Androl 2002; 4:281-285.
44. Menkveld R, Rhmerev JP, Franken DR, Vermeiden JP, Kruger TF. Acrosmal morphology as a novel criterion for male fertility diagnosis: relationship with acrosin activity, morphology (strict criteria) and fertilization in vitro. Fertil Steril 1996; 65:637-644.
45. Coetzee K, Kruger TF, Lombard CJ. Predictive value of normal sperm morphology: a structured literature review. Hum Reprod Update 1998; 4:73-82.
46. Said TM, Aziz N, Sharma RK, Lewis-Jones I, Thomas AJ Jr, Agarwal A. Novel association between sperm deformity index and oxidative stress-induced DNA damage in infertile male patients. Asian J Androl 2005; 7:121-126.
47. Mahadevan MM, Trounson AO. The influence of seminal characteristics on the success rate of human in vitro fertilization. Fertil Steril 1984; 42:400-405.
48. Liu DY, Baker HWG. Relationship between human acrosin, acrosomes, morphology and fertilization in vitro. Hum Reprod 1990; 5:298-303.
49. Grow DR, Oehninger DS, Seltman HJ, Toner JP, Swanson RJ, Kruger TF, Muasher SJ. Sperm morphology as diagnosed by strict criteria: probing the impact of teratozoospermia on fertilization rate and pregnancy outcome in a large in vitro fertilization population. Fertil Steril 1994; 62:559-567.
50. Kruger TF, Acosta AA, Simmons KF, Swanson RJ, Matta JF, Oehninger S. Predictive value of abnormal sperm morphology in vitro fertilization. Fertil Steril 1988; 49:112-117.
51. Berkovitz A, Eltes F, Lederman H, Peer S, Ellenbongen A, Feldberg B, Bartoov B. How to improve IVF-ICSI outcomes by sperm selection. Reprod Biomed Online 2006; 12:634-638.
52. Gianaroli L, Magli MC, Collodel G, Moretti E, Ferraretti AP, Baccetti B. Sperm head's birefringence: a new criterion for sperm selection. Fertil Steril 2008; 90:104-112.
53. Kumar S, Sathawara NG, Gautman AK, Agarwal K, Shah B, Kulkarni PK, Patel K, Patel A, Dave LM, Parikh DJ, Saiyed HN. Semen quality of industrial workers occupationally exposed to chromium. J Occup Health 2005; 47:424-530.
54. Huang I, Jones J, Khorram O. Human seminal plasma nitric oxide: correlation with sperm morphology and testosterone. Med Sci Monit 2006; 12:103-106.
55. Kuriyama K, Kitamura T, Yokoi R, Hayashi M, Kobaiashi K, Kuroda J, Tsuji H. Evaluation of testicular toxicity and sperm morphology in rats treated with methyl methanesulphonate [MMS]. J Reprod Dev 2005; 51:657-667.
56. Sun F, Ko E, Martin RH. Is there a relationship between sperm chromosome abnormalities and sperm morphology? Reprod Biol Endocrinol 2006; 41:1-15.
57. Viville S, Mollard R, Bach ML, Falquet C, Gerlinger P, Waeter S. Do morphological anomalies reflect chromosomal aneuplodies? Case report. Hum Reprod 2000; 15:2563-2566.
58. Rives N, Mousset Simeon N, Mazurier S, Mace B. Primary flagellar abnormality is associated with an increased rate of spermatozoa aneuploidy. J Androl 2005; 26:61-69.
59. Mateu E, Rodrigo L, Prados N, Gil-Salom M, Remohi J, Pellicer A, Rubio C. High incidence of chromosomal abnormalities in large headed and multiple tailed spermatozoa. J Androl 2006; 27:6-10.
60. Prisant N, Escalier D, Soufir JC, Morillon M, Schoevart D, Misrahi M, Tachdjian G. Ultrastructural nuclear defects and increased chromosome aneuploidies in spermatozoa with elongated heads. Hum Reprod 2007; 22:1052-1059.
61. Strassburger D, Reichart M, Kaufman S, Kasterstein E, Komarovsky D, Bern O, Friedler S, Schachter M, Ron-El R, Raziel A. Morphology assessment and fluorescence in situ hibridation of the same spermatozoon using a computerized cell-scanning system. Hum Reprod 2007; 22:201-209.
62. Vegetti W, Van Assche E, Frias A, Verheyen G, Bianchi MM, Bonduelle M, Liebaers I, Van Steirteghem A. Correlation between semen parameters and sperm aneuploidy rates investigated by fluorescence in situ hybridation in infertile men. Hum Reprod 2000; 15:351-365.
63. Burrello N, Arcidiacono G, Vicari E, Asero P, Di Benedetto D, De Palma A, Romeo R, D'Agata R, Calogero AE. Morphologically normal spematozoa of patients with secretory oligo-astheno-teratozoospermia have an increased aneuploidy rate. Hum Reprod 2004; 19:2298-2302.
64. De Palma A, Burrello N, Barone N, D'Agata R, Vicari E, Calogero AE. Patients with abnormal sperm parameters have an increased sex chromosomes aneuploidy rate in peripheral leukocytes. Hum Reprod 2005; 20:2153-2156.
65. Mudrak O, Tomilin N, Zalenski A. Chromosome architecture in the decondensing human sperm nucleous. J Cell Sci 2005; 118:4541-4550.
66. Foster HA, Abeydeera LR, Griffin DK, Bridger JM. Non-random chromosome positioning in mammalian sperm nuclei, with migration of the sex chromosomes during late spermatogenesis. J Cell Sci 2005; 118:1811-1820.
67. Gianaroli L, Magli MC, Ferraretti AP. Sperm and blastomere aneuploidy detection in reproductive genetics and medicine. J Histochem Cytochem 2005; 53:261-267.