Application of high-speed counter-current chromatography for the isolation of antiviral eremophilenolides from Ligularia atroviolacea

Biomedical Chromatography

Volumn 22, Issue 9, 2008, Pages 985-991

  Shi, Shu Yun ^a   Zhou, Hong Hao ^a   Huang, Ke Long ^a   Li, Hai Bo ^b   Liu, Su Qin ^a   Zhao, Yu ^c  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b Nantong Center for Disease Control and Prevention   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

Antiviral activity; Eremophilenolides; Hepatitis B virus; High speed counter current chromatography; Ligularia atroviolacea; Preparation

Indexed keywords

BIOASSAY; CELL CULTURE; LIQUID CHROMATOGRAPHY; MEDICINE; PURIFICATION; VIRUSES;

ANTIVIRAL ACTIVITIES; ANTIVIRALS; EREMOPHILENOLIDES; ETHYL-ACETATE; HEPATITIS B VIRUS; HEPG2.2.15 CELLS; HIGHSPEED COUNTERCURRENT CHROMATOGRAPHIES (HSCCC); LIGULARIUM ATROVIOLACEA; PREPARATION; SURFACE ANTIGEN;

ORGANIC SOLVENTS;

8BETA HYDROXYEREMOPHIL 3,7(11)DIEN 12,8ALPHA,15,6ALPHA DIOLIDE; 8BETA METHOXYEREMOPHIL 3,7(11)DIEN 12,8ALPHA,15,6ALPHA DIOLIDE; ACETIC ACID ETHYL ESTER; EREMOPHILENOLIDE DERIVATIVE; HEPATITIS B SURFACE ANTIGEN; LAMIVUDINE; LIGULARIA ATROVIOLACEA EXTRACT; METHANOL; PETROLEUM; PLANT EXTRACT; TERPENOID; TERPENOID DERIVATIVE; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ANTIVIRAL ACTIVITY; ARTICLE; ASTERACEAE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL STRAIN HEPG2; CONTROLLED STUDY; COUNTER CURRENT CHROMATOGRAPHY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG PURIFICATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; LIGULARIA ATROVIOLACEA; NONHUMAN; PHYTOCHEMISTRY; PROCESS DEVELOPMENT; PROTON NUCLEAR MAGNETIC RESONANCE; SOLVENT EXTRACTION; VIRUS INHIBITION;

HEPATITIS B VIRUS; LIGULARIA;

EID: 53349098149     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1017     Document Type: Article

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