Smenospongine, a sesquiterpene aminoquinone from a marine sponge, induces G1 arrest or apoptosis in different leukemia cells

Marine Drugs

Volumn 6, Issue 3, 2008, Pages 480-488

  Kong, Dexin ^a,c   Aoki, Shunji ^a   Sowa, Yoshihiro ^b   Sakai, Toshiyuki ^b   Kobayashi, Motomasa ^a  

^a OSAKA UNIVERSITY   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c CANCER CHEMOTHERAPY CENTER   (Japan)

Author keywords

Apoptosis; G1 arrest; Leukemia cells; P21; Rb; Smenospongine

Indexed keywords

ANTINEOPLASTIC AGENT; PROTEIN P21; RETINOBLASTOMA PROTEIN; SMENOSPONGINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL STRAIN HL 60; CELL STRAIN K 562; CELL STRAIN U937; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; FLOW CYTOMETRY; GENE ACTIVATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION;

DACTYLOSPONGIA ELEGANS;

EID: 53349096248     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md20080023     Document Type: Article

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