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Volumn 3, Issue 3, 2008, Pages 171-183

Ultrafine titanium dioxide nanoparticles induce cell death in human bronchial epithelial cells

Author keywords

Airway cells; Nanoparticle; Titanium dioxide; UV absent nanotoxicity

Indexed keywords

CELL DEATH; OXIDES; TITANIUM; TITANIUM DIOXIDE;

EID: 53349095638     PISSN: 17458080     EISSN: 17458099     Source Type: Journal    
DOI: 10.1080/17458080802412430     Document Type: Article
Times cited : (23)

References (53)
  • 1
    • 0036055464 scopus 로고    scopus 로고
    • Evidence that ultrafine titanium dioxide induces micronuclei and apoptosis in Syrian hamster embryo fibroblasts
    • Rahman, Q., Lohani, M., Dopp, E., Pemsel, H., Weiss, DG and Schiffmann, D. (2002) Evidence that ultrafine titanium dioxide induces micronuclei and apoptosis in Syrian hamster embryo fibroblasts. Environ. Health Perspect., 110:8, pp. 797-800.
    • (2002) Environ. Health Perspect. , vol.110 , Issue.8 , pp. 797-800
    • Rahman, Q.1    Lohani, M.2    Dopp, E.3    Pemsel, H.4    Weiss, D.G.5    Schiffmann, D.6
  • 2
    • 0024273585 scopus 로고
    • Titanium dioxide induced chemiluminescence of human polymorphonuclear leukocytes
    • Hedenborg, M. (1988) Titanium dioxide induced chemiluminescence of human polymorphonuclear leukocytes. Int. Arch. Occup. Environ. Health, 61:1, pp. 1-6.
    • (1988) Int. Arch. Occup. Environ. Health , vol.61 , Issue.1 , pp. 1-6
    • Hedenborg, M.1
  • 3
    • 0025349238 scopus 로고
    • Toxicology and carcinogenesis studies of dietary titanium dioxide-coated mica in male and female Fischer 344 rats
    • Bernard, BK, Osheroff, MR, Hofmann, A. and Mennear, JH (1990) Toxicology and carcinogenesis studies of dietary titanium dioxide-coated mica in male and female Fischer 344 rats. J. Toxicol. Environ. Health, 29:4, pp. 417-429.
    • (1990) J. Toxicol. Environ. Health , vol.29 , Issue.4 , pp. 417-429
    • Bernard, B.K.1    Osheroff, M.R.2    Hofmann, A.3    Mennear, J.H.4
  • 4
    • 0024232134 scopus 로고
    • Epidemiologic study of workers exposed to titanium dioxide
    • Chen, JL and Fayerweather, WE (1988) Epidemiologic study of workers exposed to titanium dioxide. J. Occup. Med., 30:12, pp. 937-942.
    • (1988) J. Occup. Med. , vol.30 , Issue.12 , pp. 937-942
    • Chen, J.L.1    Fayerweather, W.E.2
  • 5
    • 0031914450 scopus 로고    scopus 로고
    • In vitro toxicity of respirable-size particles of diatomaceous earth and crystalline silica compared with asbestos and titanium dioxide
    • Hart, GA and Hesterberg, TW (1998) In vitro toxicity of respirable-size particles of diatomaceous earth and crystalline silica compared with asbestos and titanium dioxide. J. Occup. Environ. Med., 40:1, pp. 29-42.
    • (1998) J. Occup. Environ. Med. , vol.40 , Issue.1 , pp. 29-42
    • Hart, G.A.1    Hesterberg, T.W.2
  • 7
    • 23944463473 scopus 로고    scopus 로고
    • Ultrafine titanium dioxide particles in the absence of photoactivation can induce oxidative damage to human bronchial epithelial cells
    • Gurr, JR, Wang, AS, Chen, CH and Jan, KY (2005) Ultrafine titanium dioxide particles in the absence of photoactivation can induce oxidative damage to human bronchial epithelial cells. Toxicology, 213:1, pp. 66-73.
    • (2005) Toxicology , vol.213 , Issue.1 , pp. 66-73
    • Gurr, J.R.1    Wang, A.S.2    Chen, C.H.3    Jan, K.Y.4
  • 8
    • 0037241858 scopus 로고    scopus 로고
    • Development, and validation of a high-throughput method for the determination of titanium dioxide in rodent lung and lung-associated lymph node tissues
    • Levine, KE, Fernando, RA, Lang, M., Essader, A. and Wong, BA (2003) Development, and validation of a high-throughput method for the determination of titanium dioxide in rodent lung and lung-associated lymph node tissues. Anal. Lett., 36:3, pp. 563-576.
    • (2003) Anal. Lett. , vol.36 , Issue.3 , pp. 563-576
    • Levine, K.E.1    Fernando, R.A.2    Lang, M.3    Essader, A.4    Wong, B.A.5
  • 9
    • 0141849021 scopus 로고    scopus 로고
    • Assessment of the skin photoprotective capacities of an organo-mineral broad-spectrum sunblock on two ex vivo skin models
    • Gelis, C., Girard, S., Mavon, A., Delverdier, M., Paillous, N. and Vicendo, P. (2003) Assessment of the skin photoprotective capacities of an organo-mineral broad-spectrum sunblock on two ex vivo skin models. Photodermatol. Photoimmunol. Photomed., 19:5, pp. 242-253.
    • (2003) Photodermatol. Photoimmunol. Photomed. , vol.19 , Issue.5 , pp. 242-253
    • Gelis, C.1    Girard, S.2    Mavon, A.3    Delverdier, M.4    Paillous, N.5    Vicendo, P.6
  • 10
    • 0036183331 scopus 로고    scopus 로고
    • Fine and ultrafine particles of the diet: Influence on the mucosal immune response and association with Crohn's disease
    • Lomer, MC, Thompson, RP and Powell, JJ (2002) Fine and ultrafine particles of the diet: Influence on the mucosal immune response and association with Crohn's disease. Proc. Nutr. Soc., 61:1, pp. 123-130.
    • (2002) Proc. Nutr. Soc. , vol.61 , Issue.1 , pp. 123-130
    • Lomer, M.C.1    Thompson, R.P.2    Powell, J.J.3
  • 11
    • 0037014524 scopus 로고    scopus 로고
    • Environmental catalysis: Trends and outlook
    • Centi, G., Ciambelli, P., Perathoner, S. and Russo, P. (2002) Environmental catalysis: Trends and outlook. Catal. Today, 75:1, pp. 3-15.
    • (2002) Catal. Today , vol.75 , Issue.1 , pp. 3-15
    • Centi, G.1    Ciambelli, P.2    Perathoner, S.3    Russo, P.4
  • 12
    • 0036707780 scopus 로고    scopus 로고
    • Heterogeneous water phase catalysis as an environmental application: A review
    • Pirkanniemi, K. and Sillanpaa, M. (2002) Heterogeneous water phase catalysis as an environmental application: A review. Chemosphere, 48:10, pp. 1047-1060.
    • (2002) Chemosphere , vol.48 , Issue.10 , pp. 1047-1060
    • Pirkanniemi, K.1    Sillanpaa, M.2
  • 13
    • 0035003835 scopus 로고    scopus 로고
    • Titanium dioxide: Environmental white knight?
    • Frazer, L. (2001) Titanium dioxide: Environmental white knight?. Environ. Health Perspect., 109:4, p. A174.
    • (2001) Environ. Health Perspect. , vol.109 , Issue.4
    • Frazer, L.1
  • 14
    • 2442478632 scopus 로고    scopus 로고
    • Photo-irradiated titanium dioxide catalyzes site specific DNA damage via generation of hydrogen peroxide
    • Hirakawa, K., Mori, M., Yoshida, M., Oikawa, S. and Kawanishi, S. (2004) Photo-irradiated titanium dioxide catalyzes site specific DNA damage via generation of hydrogen peroxide. Free Radic. Res., 38:5, pp. 439-447.
    • (2004) Free Radic. Res. , vol.38 , Issue.5 , pp. 439-447
    • Hirakawa, K.1    Mori, M.2    Yoshida, M.3    Oikawa, S.4    Kawanishi, S.5
  • 15
    • 0035181979 scopus 로고    scopus 로고
    • Ultraviolet irradiation of titanium dioxide in aqueous dispersion generates singlet oxygen
    • Konaka, R., Kasahara, E., Dunlap, WC, Yamamoto, Y., Chien, KC and Inoue, M. (2001) Ultraviolet irradiation of titanium dioxide in aqueous dispersion generates singlet oxygen. Redox Rep., 6:5, pp. 319-325.
    • (2001) Redox Rep. , vol.6 , Issue.5 , pp. 319-325
    • Konaka, R.1    Kasahara, E.2    Dunlap, W.C.3    Yamamoto, Y.4    Chien, K.C.5    Inoue, M.6
  • 16
    • 0033790078 scopus 로고    scopus 로고
    • Excited-state properties of C(60) fullerene derivatives
    • Guldi, DM and Prato, M. (2000) Excited-state properties of C(60) fullerene derivatives. Acc. Chem. Res., 33:10, pp. 695-703.
    • (2000) Acc. Chem. Res. , vol.33 , Issue.10 , pp. 695-703
    • Guldi, D.M.1    Prato, M.2
  • 17
    • 0035526535 scopus 로고    scopus 로고
    • The history of photodetection and photodynamic therapy
    • Ackroyd, R., Kelty, C., Brown, N. and Reed, M. (2001) The history of photodetection and photodynamic therapy. Photochem. Photobiol., 74:5, pp. 656-669.
    • (2001) Photochem. Photobiol. , vol.74 , Issue.5 , pp. 656-669
    • Ackroyd, R.1    Kelty, C.2    Brown, N.3    Reed, M.4
  • 18
    • 7044247906 scopus 로고    scopus 로고
    • 2 nanoparticles on Ls-174-t human colon carcinoma cells
    • 2 nanoparticles on Ls-174-t human colon carcinoma cells. World J. Gastroenterol., 10:21, pp. 3191-3193.
    • (2004) World J. Gastroenterol. , vol.10 , Issue.21 , pp. 3191-3193
    • Zhang, A.P.1    Sun, Y.P.2
  • 19
    • 0038779340 scopus 로고    scopus 로고
    • Investigations on the inflammatory and genotoxic lung effects of two types of titanium dioxide: Untreated and surface treated
    • Rehn, B., Seiler, F., Rehn, S., Bruch, J. and Maier, M. (2003) Investigations on the inflammatory and genotoxic lung effects of two types of titanium dioxide: Untreated and surface treated. Toxicol. Appl. Pharmacol., 189:2, pp. 84-95.
    • (2003) Toxicol. Appl. Pharmacol. , vol.189 , Issue.2 , pp. 84-95
    • Rehn, B.1    Seiler, F.2    Rehn, S.3    Bruch, J.4    Maier, M.5
  • 23
    • 0035337960 scopus 로고    scopus 로고
    • Asbestos causes apoptosis in alveolar epithelial cells: Role of iron-induced free radicals
    • Aljandali, A., Pollack, H., Yeldandi, A., Li, Y., Weitzman, SA and Kamp, DW (2001) Asbestos causes apoptosis in alveolar epithelial cells: Role of iron-induced free radicals. J. Lab. Clin. Med., 137:5, pp. 330-339.
    • (2001) J. Lab. Clin. Med. , vol.137 , Issue.5 , pp. 330-339
    • Aljandali, A.1    Pollack, H.2    Yeldandi, A.3    Li, Y.4    Weitzman, S.A.5    Kamp, D.W.6
  • 25
    • 3543004104 scopus 로고    scopus 로고
    • Effects of nano-scaled particles on endothelial cell function in vitro: Studies on viability, proliferation and inflammation
    • Peters, K., Unger, RE and Kirkpatrick, CJ (2004) Effects of nano-scaled particles on endothelial cell function in vitro: Studies on viability, proliferation and inflammation. J. Mater. Sci. Mater. Med., 15:4, pp. 321-325.
    • (2004) J. Mater. Sci. Mater. Med. , vol.15 , Issue.4 , pp. 321-325
    • Peters, K.1    Unger, R.E.2    Kirkpatrick, C.J.3
  • 27
    • 33750567127 scopus 로고    scopus 로고
    • Ultrafine but not fine particulate matter causes airway inflammation and allergic airway sensitization to co-administered antigen in mice
    • de Haar, C., Hassing, I., Bol, M., Bleumink, R. and Pieters, R. (2006) Ultrafine but not fine particulate matter causes airway inflammation and allergic airway sensitization to co-administered antigen in mice. Clin. Exp. Allergy., 36:11, pp. 1469-1479.
    • (2006) Clin. Exp. Allergy. , vol.36 , Issue.11 , pp. 1469-1479
    • de Haar, C.1    Hassing, I.2    Bol, M.3    Bleumink, R.4    Pieters, R.5
  • 29
    • 33845189668 scopus 로고    scopus 로고
    • Carbon black nanoparticles induce type II epithelial cells to release chemotaxins for alveolar macrophages
    • Barlow, PG, Clouter-Baker, A., Donalson, K., Maccallum, J. and Stone, V. (2005) Carbon black nanoparticles induce type II epithelial cells to release chemotaxins for alveolar macrophages. Part. Fibre Toxicol., 2, p. 11.
    • (2005) Part. Fibre Toxicol. , vol.2 , pp. 11
    • Barlow, P.G.1    Clouter-Baker, A.2    Donalson, K.3    Maccallum, J.4    Stone, V.5
  • 30
    • 33745700841 scopus 로고    scopus 로고
    • Correlating nanoscale titania structure with toxicity: A cytotoxicity and inflammatory response study with human dermal fibroblasts and human lung epithelial cells
    • Sayes, CM, Wahi, R., Kurian, PA, Liu, Y., West, JL, Ausman, KD, Warheit, DB and Colvin, VL (2006) Correlating nanoscale titania structure with toxicity: A cytotoxicity and inflammatory response study with human dermal fibroblasts and human lung epithelial cells. Toxicol. Sci., 92:1, pp. 174-185.
    • (2006) Toxicol. Sci. , vol.92 , Issue.1 , pp. 174-185
    • Sayes, C.M.1    Wahi, R.2    Kurian, P.A.3    Liu, Y.4    West, J.L.5    Ausman, K.D.6    Warheit, D.B.7    Colvin, V.L.8
  • 34
    • 20644449754 scopus 로고    scopus 로고
    • Nanotoxicology: An emerging discipline evolving from studies of ultrafine particles
    • Oberdorster, GE, Oberdorster, E. and Oberdorster, J. (2005) Nanotoxicology: An emerging discipline evolving from studies of ultrafine particles. Environ. Health Perspect., 113:7, pp. 823-839.
    • (2005) Environ. Health Perspect. , vol.113 , Issue.7 , pp. 823-839
    • Oberdorster, G.E.1    Oberdorster, E.2    Oberdorster, J.3
  • 35
    • 33644746349 scopus 로고    scopus 로고
    • Instillation of six different ultrafine carbon particles indicates a surface area threshold dose for acute lung inflammation in mice
    • Stoeger, T., Reinhard, C., Takenaka, S., Schroeppel, A., Karg, E., Ritter, B., Heyder, J. and Schultz, H. (2006) Instillation of six different ultrafine carbon particles indicates a surface area threshold dose for acute lung inflammation in mice. Environ. Health Perspect., 114:3, pp. 328-333.
    • (2006) Environ. Health Perspect. , vol.114 , Issue.3 , pp. 328-333
    • Stoeger, T.1    Reinhard, C.2    Takenaka, S.3    Schroeppel, A.4    Karg, E.5    Ritter, B.6    Heyder, J.7    Schultz, H.8
  • 36
    • 33746890196 scopus 로고    scopus 로고
    • Daphnia magna mortality when exposed to titanium dioxide and fullerene (C-60) nanoparticles
    • Lovern, SB and Klaper, R. (2006) Daphnia magna mortality when exposed to titanium dioxide and fullerene (C-60) nanoparticles. Environ. Toxicol. Chem., 25:4, pp. 1132-1137.
    • (2006) Environ. Toxicol. Chem. , vol.25 , Issue.4 , pp. 1132-1137
    • Lovern, S.B.1    Klaper, R.2
  • 37
    • 33745619214 scopus 로고    scopus 로고
    • Research strategies for safety evaluation of nanomaterials, Part VIII: International efforts to develop risk-based safety evaluations for nanomaterials
    • Thomas, K., Aguar, P., Kawasaki, H., Morris, J., Nakanishi, J. and Savage, N. (2006) Research strategies for safety evaluation of nanomaterials, Part VIII: International efforts to develop risk-based safety evaluations for nanomaterials. Toxicol. Sci., 92:1, pp. 23-32.
    • (2006) Toxicol. Sci. , vol.92 , Issue.1 , pp. 23-32
    • Thomas, K.1    Aguar, P.2    Kawasaki, H.3    Morris, J.4    Nakanishi, J.5    Savage, N.6
  • 38
    • 24944452398 scopus 로고    scopus 로고
    • Research strategies for safety evaluation of nanomaterials, part I: Evaluating the human health implications of exposure to nanoscale materials
    • Thomas, K. and Sayre, P. (2005) Research strategies for safety evaluation of nanomaterials, part I: Evaluating the human health implications of exposure to nanoscale materials. Toxicol. Sci., 87:2, pp. 316-321.
    • (2005) Toxicol. Sci. , vol.87 , Issue.2 , pp. 316-321
    • Thomas, K.1    Sayre, P.2
  • 39
    • 0015432756 scopus 로고
    • Pulmonary deposits of titanium dioxide in man
    • Elo, R., Maatta, K., Uksila, E. and Arstila, AU (1972) Pulmonary deposits of titanium dioxide in man. Arch. Pathol., 94:5, pp. 417-424.
    • (1972) Arch. Pathol. , vol.94 , Issue.5 , pp. 417-424
    • Elo, R.1    Maatta, K.2    Uksila, E.3    Arstila, A.U.4
  • 40
    • 0019843850 scopus 로고
    • Massive pulmonary deposition of rutile after titanium dioxide exposure: Light-microscopical and physico-analytical methods in pigment identification
    • [A]
    • Rode, LE, Ophus, EM and Gylseth, B. (1981) Massive pulmonary deposition of rutile after titanium dioxide exposure: Light-microscopical and physico-analytical methods in pigment identification. Acta Pathol. Microbiol. Scand. [A], 89:6, pp. 455-461.
    • (1981) Acta Pathol. Microbiol. Scand. , vol.89 , Issue.6 , pp. 455-461
    • Rode, L.E.1    Ophus, E.M.2    Gylseth, B.3
  • 42
    • 33847256798 scopus 로고    scopus 로고
    • 2 particles in cultured human lymphoblastoid cells
    • 2 particles in cultured human lymphoblastoid cells. Mutat. Res., 628:2, pp. 99-106.
    • (2007) Mutat. Res. , vol.628 , Issue.2 , pp. 99-106
    • Wang, J.J.1    Sanderson, B.J.2    Wang, H.3
  • 43
    • 8444221217 scopus 로고    scopus 로고
    • Inflammatory cytokines and cell death in BEAS-2B lung cells treated with soil dust, lipopolysaccharide, and surface-modified particles
    • Veranth, JM, Reilly, CA, Veranth, MM, Moss, TA, Langelier, CR, Lanza, DL and Yost, GS (2004) Inflammatory cytokines and cell death in BEAS-2B lung cells treated with soil dust, lipopolysaccharide, and surface-modified particles. Toxicol. Sci., 82:1, pp. 88-96.
    • (2004) Toxicol. Sci. , vol.82 , Issue.1 , pp. 88-96
    • Veranth, J.M.1    Reilly, C.A.2    Veranth, M.M.3    Moss, T.A.4    Langelier, C.R.5    Lanza, D.L.6    Yost, G.S.7
  • 44
    • 4243403960 scopus 로고    scopus 로고
    • Asbestos-induced alveolar epithelial cell apoptosis: Role of mitochondrial dysfunction caused by iron-derived free radicals
    • Kamp, DW, Panduri, V., Weitzman, SA and Chandel, N. (2002) Asbestos-induced alveolar epithelial cell apoptosis: Role of mitochondrial dysfunction caused by iron-derived free radicals. Mol. Cell Biochem., 234235:12, pp. 153-160.
    • (2002) Mol. Cell Biochem. , vol.234-235 , Issue.1 , pp. 153-160
    • Kamp, D.W.1    Panduri, V.2    Weitzman, S.A.3    Chandel, N.4
  • 45
    • 0242331711 scopus 로고    scopus 로고
    • Silica-induced caspase activation in mouse alveolar macrophages is dependent upon mitochondrial integrity and aspartic proteolysis
    • Thibodeau, M., Giardina, C. and Hubbard, AK (2003) Silica-induced caspase activation in mouse alveolar macrophages is dependent upon mitochondrial integrity and aspartic proteolysis. Toxicol. Sci., 76:1, pp. 91-101.
    • (2003) Toxicol. Sci. , vol.76 , Issue.1 , pp. 91-101
    • Thibodeau, M.1    Giardina, C.2    Hubbard, A.K.3
  • 46
    • 33748310797 scopus 로고    scopus 로고
    • Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm
    • Xia, T., Kovochich, M., Brant, J., Hotze, M., Oberley, T., Sioutas, C., Yeh, JI, Wiesner, MR and Nel, AE (2006) Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. Nano Lett., 6:8, pp. 1794-1807.
    • (2006) Nano Lett. , vol.6 , Issue.8 , pp. 1794-1807
    • Xia, T.1    Kovochich, M.2    Brant, J.3    Hotze, M.4    Oberley, T.5    Sioutas, C.6    Yeh, J.I.7    Wiesner, M.R.8    Nel, A.E.9
  • 47
    • 1642341112 scopus 로고    scopus 로고
    • Increased viable osteoblast density in the presence of nanophase compared to conventional alumina and titania particles
    • Gutwein, LG and Webster, TJ (2004) Increased viable osteoblast density in the presence of nanophase compared to conventional alumina and titania particles. Biomaterials, 25:18, pp. 4175-4183.
    • (2004) Biomaterials , vol.25 , Issue.18 , pp. 4175-4183
    • Gutwein, L.G.1    Webster, T.J.2
  • 51
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr, JF, Wyllie, AH and Currie, AR (1972) Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer, 26:4, pp. 239-257.
    • (1972) Br. J. Cancer , vol.26 , Issue.4 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 52
    • 0028902451 scopus 로고
    • Mitotic disturbances and micronucleus induction in Syrian hamster embryo fibroblast cells caused by asbestos fibers
    • Dopp, E., Saedler, J., Stopper, H., Weiss, DG and Schiffmann, D. (1995) Mitotic disturbances and micronucleus induction in Syrian hamster embryo fibroblast cells caused by asbestos fibers. Environ. Health Perspect., 103:3, pp. 268-271.
    • (1995) Environ. Health Perspect. , vol.103 , Issue.3 , pp. 268-271
    • Dopp, E.1    Saedler, J.2    Stopper, H.3    Weiss, D.G.4    Schiffmann, D.5
  • 53
    • 0029558793 scopus 로고
    • Mineral fibers induce apoptosis in Syrian hamster embryo fibroblasts
    • Dopp, E., Nebe, B., Hahnel, C., Papp, T., Alonso, B., Simko, M. and Schiffmann, D. (1995) Mineral fibers induce apoptosis in Syrian hamster embryo fibroblasts. Pathobiology, 63:4, pp. 213-221.
    • (1995) Pathobiology , vol.63 , Issue.4 , pp. 213-221
    • Dopp, E.1    Nebe, B.2    Hahnel, C.3    Papp, T.4    Alonso, B.5    Simko, M.6    Schiffmann, D.7


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