Architecture of enteric neural circuits involved in intestinal motility

European Review for Medical and Pharmacological Sciences

Volumn 12, Issue SUPPL. 1, 2008, Pages 3-19

  Costa, Marcello ^a   Brookes, S H ^a  

^a FLINDERS UNIVERSITY   (Australia)

Author keywords

Enteric neurons; Motor patterns; Neural transmission; Spatio temporal maps

Indexed keywords

NEUROTRANSMITTER;

ADRENERGIC NERVE CELL; ADRENERGIC TRANSMISSION; CELL FUNCTION; CELL LABELING; CELL POLARITY; CELL POPULATION; CELL PROLIFERATION; CELL STRUCTURE; CHOLINERGIC TRANSMISSION; CLINICAL CHEMISTRY; GANGLION; GOLGI COMPLEX; GUINEA PIG; HISTOCHEMISTRY; HUMAN; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; INTERNEURON; INTERSTITIAL CELL OF CAJAL; INTESTINE BLOOD FLOW; INTESTINE CONTRACTION; INTESTINE INNERVATION; INTESTINE MOTILITY; MECHANICAL STIMULATION; MOTONEURON; MYENTERIC PLEXUS; NERVE FIBER TRANSPORT; NERVE POTENTIAL; NEUROANATOMY; NEUROCHEMISTRY; NEUROFILAMENT; NEUROMODULATION; NEUROMUSCULAR TRANSMISSION; NONHUMAN; NORADRENERGIC NERVE; PARASYMPATHETIC NERVE; PHYSICAL CHEMISTRY; REFLEX; REVIEW; SENSORIMOTOR FUNCTION; SENSORY NERVE CONDUCTION; SEROTONINERGIC NERVE CELL; SMOOTH MUSCLE RELAXATION;

ANIMALS; ENTERIC NERVOUS SYSTEM; GASTROINTESTINAL MOTILITY; GUINEA PIGS; HUMANS; MOTOR NEURONS; MUSCLE, SMOOTH; NEURAL PATHWAYS;

EID: 53249122038     PISSN: 11283602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (91)

1. LEGROS AND ONIMUS. Mouvements de l'intestin. J Anat Physiol (Paris) 1869; 6: 37-65.
2. CANNON WB. The Mechanical Factors of Digestion. London: Edward Arnold; 1911.
3. TRENDELENBURG P. Physiological and pharmacological investigations of small intestinal peristalsis. Naunyn-Schmiedeberg's Arch Pharmacol 2006; 373: 101-103.
4. SANDERS KM. Interstitial cells of Cajal at the clinical and scientific interface. J Physiol Lond 2006; 576: 683-687.
5. SANDERS KM, KOH SD, WARD SM. Interstitial cells of Cajal as pacemakers in the gastrointestinal tract. Annu Rev Physiol 2006; 68: 307-343.
6. FURNESS JB, COSTA M. The Enteric Nervous System. Edinburgh: Churchill-Livingstone; 1987.
7. FURNESS JB. The Enteric Nervous System. Cambridge: Blackwell Publishing; 2006.
8. BORNSTEIN JC, COSTA M, GRIDER JR. Enteric motor and interneuronal circuits controlling motility. Neurogastroenterol Motil 2004; 16 (Suppl 1): 34-38.
9. BROOKES SJH, COSTA M. Functional Histoanatomy of the Enteric Nervous System. In: Johnson LR, ed. Physiology of the Gastrointestinal Tract (4th Ed). Elsevier; 2006.
10. BROOKES SJH, COSTA M. Cellular Organisation of the Mammalian Enteric Nervous System. In Brookes SJH, Costa M eds. Innervation of the Gastrointestinal Tract. Geoffrey Burnstock, Series ed. The Autonomic Nervous System. London: Taylor and Francis; 2002.
11. BAYLISS WM, STARLING EH. The movements and innervation of the small intestine. J Physiol Lond 1899; 24: 99-143.
12. MAGNUS R. Die Bewegungen des Verdauungskanals. Rev Physiol Biochem Expl Pharmacol 1905; 7: 27-64.
13. DOGIEL AS. Über den Bau der Ganglien in den Geflechten des Darmes und der Gallenblase des Menschen und der Säugethiere. Arch Anat Physiol Leipzig, Anat Abt Jg 1899; 130-158.
14. PATON WDM. The response of the guinea-pig to electrical stimulation by coaxial electrodes. J Physiol Lond 1955; 127: 40-41P.
15. AMBACHE N, VERNEY J, ZAR MA. Evidence for the release of two atropine-resistant spasmogens from Auerbach's plexus. J Physiol Lond 1970; 207: 761-782.
16. MUNRO AF. The effect of adrenaline on the guinea-pig intestine. J Physiol Lond 1951; 112: 84-94.
17. COSTA M, FURNESS JB. The sites of action of 5-hydroxytryptamine in nerve muscle preparations from the guinea-pig small intestine and colon. Br J Pharmacol 1979; 65: 237-248.
18. COSTA M, FURNESS JB, PULLIN CO, BORNSTEIN J. Substance P enteric neurons mediate non-cholinergic transmission to the circular muscle of the guinea-pig intestine. Naunyn-Schmiedeberg's Arch Pharmacol 1985; 328: 446-453.
19. BURNSTOCK G, CAMPBELL G, RAND MJ. The inhibitory innervation of the taenia of the guinea-pig caecum. J Physiol Lond 1966; 182: 504-526.
20. BENNETT MR. Non-adrenergic non-cholinergic (NANC) transmission to smooth muscle: 35 years on. Prog Neurobiol 1997; 52:159-195.
21. LANGLEY JN. The Autonomic Nervous System. Cambridge: Heffer; 1921.
22. BURNSTOCK G, COSTA M. Inhibitory innervation of the gut. Gastroenterology 1973; 64: 141-144.
23. KOSTERLITZ HW, PIRIE VW, ROBINSON JA. The mechanism of the peristaltic reflex in the isolated guinea-pig ileum. J Physiol Lond 1956; 133: 681-694.
24. CREMA A, FRIGO, FRIGO GM, LECCHINI S. A pharmacological analysis of the peristaltic reflex in the isolated colon of the guinea-pig or cat. Br J Pharmacol 1970; 39: 334-345.
25. COSTA M, FURNESS JB. The peristaltic reflex: An analysis of the nerve pathways and their pharmacology. Naunyn-Schmiedeberg's Arch Pharmacol 1976; 294: 47-60.
26. TONINI M, FRIGO, FRIGO GM, LECCHINI S, D'ANGELO S AND CREMA A. Hyoscine-resistant peristalsis in guinea-pig ileum. Eur J Pharmacol 1981; 71: 375-381.
27. 2 receptor-mediated control of peristaltic propulsion in the guinea-pig small intestine in vitro. Neuropharmacology 1998; 37: 131-138.
28. HUIZINGA JD, AMBROUS K, DERSILAPHET T. Co-operation between neural and myogenic mechanisms in the control of distension-induced peristalsis in the mouse small intestine. J Physiol Lond 1998; 506: 843-856.
29. HENNIG GW, COSTA M, CHEN BN, BROOKES SJH. Quantitative analysis of peristalsis in the guinea-pig small intestine using spatio-temporal maps. J Physiol Lond 1999; 517: 575-590.
30. SPENCER NJ, SMITH C B, SMITH TK. Role of muscle tone in peristalsis in guinea-pig small intestine. J Physiol Lond 2001; 530: 295-306.
31. COSTA M, FURNESS JB. Immunohistochemistry on whole mount preparations. In: Cuello AC ed. Immunohistochemistry. IBRO Handbook Series, Methods in the Neurosciences, Wiley; 1982.
32. STEELE P, BROOKES S, COSTA M. Immunohistochemical identification of cholinergic neurons in the myenteric plexus of guinea-pig small intestine. Neuroscience 1991; 45: 227-239.
33. COSTA M, ROBECCHI MG. Sulla presenza di fibre adrenergiche nel mesentere e nella parete del canale alimentare. Boll Soc Ital Biol Sper 1965; 4: 1106-1108.
34. COSTA M, FURNESS JB, CUELLO AC, VERHOFSTAD AA, STEINBUSCH HW, ELDE RP . Neurons with 5-hydroxytryptamine-like immunoreactivity in the enteric nervous system: Their visualization and reactions to drug treatment. Neuroscience 1982; 7: 351-363.
35. BORNSTEIN JC, NORTH RA, COSTA M, FURNESS JB. Excitatory synaptic potentials due to activation of neurons with short projections in the myenteric plexus. Neuroscience 1984; 11: 723-731.
36. HÖKFELT T, JOHANSSON O, LJUNGDAHL A, LUNDBERG JM, SCHULZBERG M . Peptidergic neurones. Nature 1980; 284: 515-521.
37. COSTA M, FURNESS JB. Neuronal peptides in the intestine. Br Med Bull 1982; 38: 247-252.
38. COSTA M, FURNESS JB, GIBBINS IL. Chemical coding of enteric neurons. In: Hökfelt T, Changeux P eds. Progr Br Res. Amsterdam: Elsevier; 1986.
39. BROOKES SJH, COSTA M. Identification of enteric motor neurones which innervate the circular muscle of the guinea pig small intestine. Neurosci Lett 1990; 118: 227-230.
40. BROOKES SJH, STEELE PA, COSTA M. Identification and immunohistochemistry of cholinergic and non-cholinergic circular muscle motor neurones in the guinea pig small intestine. Neuroscience 1991; 42: 863-878.
41. WILSON AJ, LLEWELLYN-SMITH IJ, FURNESS JB, COSTA M. The source of the nerve fibres forming the deep muscular and circular muscle plexuses in the guinea-pig small intestine. Cell Tiss Res 1987; 247: 497-504.
42. FURNESS JB, LLOYD KC, STERNINI C, WALSH JH. Projections of substance P, vasoactive intestinal peptide and tyrosine hydroxylase immunoreactive nerve fibres in the canine intestine, with special reference to the innervation of the circular muscle. Arch Histol Cytol 1990; 53: 129-140.
43. FAHRENKRUG J. Vasoactive intestinal polypeptide: Measurement, distribution and putative neurotransmitter function. Digestion 1979; 19: 149-169.
44. LLEWELLYN-SMITH IJ, FURNESS JB, COSTA M. Quantitative ultrastructural analysis of enkephalin-, substance P-, and vip- immunoreactive nerve fibers in the circular muscle of the guinea-pig small intestine. J Comp Neurol 1988; 272: 139-148.
45. COSTA M, FURNESS B., POMPOLO S, BROOKES SJH, BORNSTEIN JC, BREDT DS, SNYDER S. Projections and chemical coding of neurons with immunoreactivity for nitric oxide synthase in the guinea pig small intestine. Neurosci Lett 1992; 148: 121-125.
46. FURNESS JB, COSTA M. The nervous release and the action of substances which affect intestinal muscle through neither adrenoreceptors nor cholinoreceptors. Phil Trans R Soc Lond B 1973; 265: 123-133.
47. BURNSTOCK G. Purinergic nerves. Pharmacol Rev 1972; 24: 509-577.
48. BURNSTOCK G. Physiology and pathophysiology of purinergic neurotransmission. Physiol Rev 2007; 87: 659-797.
49. SAID SI. The discovery of VIP: Initially looked for in the lung, isolated from intestine, and identified as a neuropeptide. Peptides 2007; 28: 1620-1621.
50. LARSSON LI, FAHRENKRUG J, SCHAFFALITZKY DE MUCKADELL O, SUNDLER F, HÅKANSON R, REHFELD JR. Localization of vasoactive intestinal polypeptide (VIP) to central and peripheral neurons. Proc Natl Acad Sci USA 1976; 73: 3197-3200.
51. GRIDER JR, CABLE MB, BITAR KN, SAID SI, MAKHLOUF GM. Vasoactive intestinal peptide; Relaxant neurotransmitter in tenia coli of the guinea pig. Gastroenterology 1985; 89: 36-42.
52. COSTA M, FURNESS JB, HUMPHREYS CMS. Apamin distinguishes two types of relaxation mediated by enteric nerves in the guinea-pig gastrointestinal tract. Naunyn-Schmiedeberg's Arch Pharmacol 1986; 332: 79-88.
53. FURCHGOTT RF. Endothelium-derived relaxing factor: Discovery, early studies, and identification as nitric oxide. Biosci Rep 1999; 19: 235-251.
54. BULT H, BOECKXSTAENS GE, PELCKMANS PA, JORDAENS FH, VAN MAERCKE YM, HERMAN AG. Nitric oxide as an inhibitory non-adrenergic non-cholinergic neurotransmitter. Nature 1990; 345: 346-347.
55. LLEWELLYN-SMITH IJ, SONG Z-M, COSTA M, BREDT DS, SNYDER SH. Ultrastructural localization of nitric oxide synthase immunoreactivity in guinea-pig enteric neurons. Brain Res 1992; 577: 337-342.
56. BROOKES SJH, STEELE PA, COSTA M. Calretinin immunoreactivity in cholinergic motor neurones, interneurons and vasomotor neurones in the guinea-pig small intestine. Cell Tiss Res 1991; 263: 471-481.
57. LLEWELLYN-SMITH IJ, COSTA M, FURNESS JB, BORNSTEIN JC. Structure of the tertiary component of the myenteric plexus in the guinea-pig small intestine. Cell Tiss Res 1993; 272: 509-516.
58. VICKERS JC, COSTA M. The neurofilament triplet is present in distinct subpopulations of neurons in the central nervous system of the guinea-pig. Neuroscience 1992; 49: 73-100.
59. COSTA M, BROOKES S, STEELE P, VICKERS J. Chemical coding of neurons in the gastrointestinal tract. Adv Exp Med Biol 1991; 298: 17-27.
60. NISHI S, NORTH RA. Intracellular recording from the myenteric plexus of the guinea-pig ileum. J Physiol Lond 1973; 231: 471-491.
61. HIRST GDS, HOLMAN ME, SPENCE I. Two types of neurones in the myenteric plexus of duodenum in the guinea-pig. J Physiol Lond 1974; 236: 303-326.
62. GABELLA G. Detection of nerve cells by a histochemical technic. Experientia. 1969; 25: 218-219.
63. COSTA M, BROOKES SJH, STEELE PA, GIBBINS IL, BURCHER E, KANDIAH CJ . Neurochemical classification of myenteric neurons in the guinea-pig ileum. Neuroscience 1996; 75: 949-967.
64. FURNESS JB, JL MORRIS, GIBBINS IL, COSTA M. Chemical coding of neurons and plurichemical transmission. Annu Rev Pharmacol Toxicol 1989; 29: 289-306.
65. PORTER AJ, WATTCHOW DA, HUNTER A, COSTA M. Abnormalities of nerve fibres in the circular muscle of patients with slow transit constipation. Int J Colorect Dis 1998; 13: 208-216.
66. PORTER AJ, WATTCHOW DA, BROOKES SJH, COSTA M. The neurochemical coding and projections of circular muscle motor neurons in the human colon. Gastroenterology 1997; 113: 1916-1923
67. WATERMAN SA, COSTA M, TONINI M. Modulation of peristalsis in the isolated guinea-pig small intestine by exogenous and endogenous opioids. Br J Pharmacol 1992; 106: 1004-1010.
68. BROOKES SJH. Retrograde tracing of enteric neuronal pathways. Neurogastroenterol Motil 2001; 13: 1-18
69. FURNESS JB, JOHNSON PJ, POMPOLO S, BORNSTEIN JC. Evidence that enteric motility reflexes can be initiated through entirely intrinsic mechanisms in the guinea-pig small intestine. Neurogastroenterol Motil 1995; 7: 89-96.
70. GRIDER JR. CGRP as a transmitter in the sensory pathway mediating peristaltic reflex. Am J Physiol 1994; 266: G1139-G1145.
71. BORNSTEIN JC, FURNESS JB, KUNZE WAA. Electro-physiological characterization of myenteric neurons-How do classification schemes relate. J AutonNerv Syst 1994; 48: 1-15.
72. WOOD JD. Application of classification schemes to the enteric nervous system. J Auton Nerv Syst 1994; 48: 17-29.
73. BROOKES SJH, SONG Z-M. RAMSAY G, COSTA M. Long aboral projections of Dogiel type II, AH neurons within the myenteric plexus of the guinea-pig small intestine. J Neurosci 1995; 15: 4013-4022.
74. FURNESS J B, TRUSSELL DC, POMPOLO S, BORNSTEIN JC, SMITH TK. Calbindin neurons of the guinea-pig small intestine: Quantitative analysis of their numbers and projections. Cell Tissue Res 1990; 260: 261-272.
75. SMITH TK, SPENCER NJ, HENNIG GW, DICKSON EJ. Recent advances in enteric neurobiology: Mechanosensitive interneurons. Neurogastroenterol Motil 2007; 19: 869-878.
76. SHERRINGTON CS. The Integrative Action of the Nervous System. New York: Charles Scribner's Sons; 1906.
77. BROOKES SJH, CHEN BN, COSTA M, HUMPHREYS CM. Initiation of peristalsis by circumferential stretch of flat sheets of guinea-pig ileum. J Physiol Lond 1999; 516: 525-538.
78. BROOKES SJH, D'ANTONA G, ZAGORODNYUK VP, HUMPHREYS CMS, COSTA M. Propagating contractions of the circular muscle evolked by slow stretch in flat sheets of guinea-pig ileum. Neurogastroepterol Motil 2001; 13: 519-531.
79. SPENCER NJ, SMITH CB, SMITH TK. Role of muscle tone in peristalsis in guinea-pig small intestine. J Physiol Lond 2001; 530: 295-306.
80. TONINI M, COSTA M, BROOKES SJH, HUMPHREYS CM. Dissociation of the ascending excitatory reflex from peristalsis in the guinea-pig small intestine. Neuroscience 1996; 73: 287-297.
81. THOMAS EA, BERTRAND PP, BORNSTEIN JC. A computer simulation of recurrent, excitatory networks of sensory neurons of the gut in guinea-pig. Neurosci Lett 2000; 287: 137-140.
82. KUNZE WA, FURNESS JB. The enteric nervous system and regulation of intestinal motility. Annu Rev Physiol 1999; 61: 117-142.
83. COSTA M, HUMPHREYS C, HENNIG G, BROOKES SJH. Differences in neurally mediated motor patterns initiated by mechanical stimulation along the guinea-pig large intestine. Proc Austr Neurosci Soc 2004; 15.
84. GRILLNER S, PARKER D, EL MANIRA A. Vertebrate locomotion: A lamprey perspective. Ann N Y Acad Sci 1998; 860: 1-18.
85. DE SCHUTTER E, EKEBERG O, KOTALESKI JH, ACHARD P, LANSNER A. Biophysically detailed modelling of microcircuits and beyond. Trends Neurosci 2005; 28: 562-569.
86. GALLIGAN JJ, COSTA M, FURNESS JB. Gastrointestinal myoelectric activity in the conscious guinea-pig. Am J.Physiol 1985; 249: G92-G99.
87. SMITH TK. Spontaneous junction potentials and slow waves in the circular muscle of isolated segments of guinea-pig ileum. J Auton Nerv Syst 1989; 27: 147-154.
88. BERCIK P, BOULEY L, DUTOIT P, BLUM AL, KUCERA P. Quantitative analysis of intestinal motor patterns: Spatiotemporal organization of non-neural pacemaker sites in the rat ileum. Gastroenterology 2000; 119: 386-394.
89. BENARD T, BOUCHOUCHA M, DUPRES M, CUGNENC PH. In vitro analysis of rat intestinal wall movements at rest and during propagated contraction: a new method. Am J Physiol 1997; 273: G776-784.
90. D'ANTONA G, HENNIG GW, COSTA M, HUMPHREYS CM, BROOKES SJH. Analysis of motor patterns in the isolated guinea-pig large intestine by spatio-temporal maps. Neurogastroenterol Motil 2001; 13: 483-492.
91. BERTHOUD H-R, HENNIG G, CAMPBELL M, VOLAUFOVA J, COSTA M. Video-based spatio-temporal maps for analysis of gastric motility in vitro: Effects of vagal stimulation in guinea-pigs. Neurogastroenterol Motil 2002; 14: 677-688.