Endosulfan modulates estrogen-dependent genes like a non-uterotrophic dose of 17β-estradiol

Reproductive Toxicology

Volumn 26, Issue 2, 2008, Pages 138-145

  Varayoud, Jorgelina ^a   Monje, Lucas ^a   Bernhardt, Tania ^a   Muñoz de Toro, Mónica ^a   Luque, Enrique H ^a   Ramos, Jorge G ^a  

^a UNIVERSIDAD NACIONAL DEL LITORAL   (Argentina)

Author keywords

17 Estradiol; Complement factor 3; Endosulfan; Estrogen receptor; Progesterone receptor; Uterus; Xenoestrogens

Indexed keywords

COMPLEMENT COMPONENT C3; ENDOCRINE DISRUPTOR; ENDOSULFAN; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; MESSENGER RNA; ORGANOCHLORINE INSECTICIDE; PROGESTERONE RECEPTOR; SESAME SEED OIL; UNCLASSIFIED DRUG; XENOESTROGEN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ESTROGEN ACTIVITY; FEMALE; GENE CONTROL; GENE EXPRESSION REGULATION; HORMONE RESPONSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OVARIECTOMY; PRENATAL EXPOSURE; RAT; REAL TIME POLYMERASE CHAIN REACTION; UTERUS WEIGHT; VAGINA SMEAR;

ANIMALS; CELL SIZE; COMPLEMENT C3; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOSULFAN; EPITHELIAL CELLS; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGENS, NON-STEROIDAL; FEMALE; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; ORGAN SIZE; RATS; RATS, WISTAR; RECEPTORS, PROGESTERONE; RNA, MESSENGER; UTERUS;

ANIMALIA; RATTUS; SESAMUM INDICUM;

EID: 53249118908     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2008.08.004     Document Type: Article

References (41)

1. Colborn T., vom Saal F.S., and Soto A.M. Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environ Health Perspect 101 (1993) 378-384
2. Ramos J.G., Varayoud J., Kass L., Rodriguez H., Costabel L., Muñoz-de-Toro M., and Luque E.H. Bisphenol A induces both transient and permanent histofunctional alterations of the hypothalamic-pituitary-gonadal axis in prenatally exposed male rats. Endocrinology 144 (2003) 3206-3215
3. Stoker C., Rey F., Rodriguez H., Ramos J.G., Sirosky P., Larriera A., Luque E.H., and Muñoz-de-Toro M. Sex reversal effects on Caiman latirostris exposed to environmentally relevant doses of the xenoestrogen bisphenol A. Gen Comp Endocrinol 133 (2003) 287-296
4. Muñoz-de-Toro M., Beldomenico H.R., Garcia S.R., Stoker C., De Jesus J.J., Beldomenico P.M., Ramos J.G., and Luque E.H. Organochlorine levels in adipose tissue of women from a littoral region of Argentina. Environ Res 102 (2006) 107-112
5. Sutherland T.D., Home I., Weir K.M., Russell R.J., and Oakeshott J.G. Toxicity and residues of endosulfan isomers. Rev Environ Contam Toxicol 183 (2004) 99-113
6. Blasco C., Lino C.M., Pico Y., Pena A., Font G., and Silveira M.I. Determination of organochlorine pesticide residues in honey from the central zone of Portugal and the Valencian community of Spain. J Chromatogr A 1049 (2004) 155-160
7. Carreño J., Rivas A., Granada A., Jose Lopez-Espinosa M., Mariscal M., Olea N., and Olea-Serrano F. Exposure of young men to organochlorine pesticides in Southern Spain. Environ Res 103 (2007) 55-61
8. ATSDR Toxicological profile for endosulfan. Agency for Toxic Substances and Disease Registry, Division of Toxicology, Atlanta, GA, 2000.
9. Marshall I., and Rutherford S. Health investigation level for endosulfan in soil. Proceedings of the fifth national workshop on the assessment of site contamination. National Environment Protection Council (Australia) (2003) 217-223
10. Hunter D.S., Hodges L.C., Vonier P.M., Fuchs-Young R., Gottardis M.M., and Walker C.L. Estrogen receptor activation via activation function 2 predicts agonism of xenoestrogens in normal and neoplastic cells of the uterine myometrium. Cancer Res 59 (1999) 3090-3099
11. Lemaire G., Mnif W., Mauvais P., Balaguer P., and Rahmani R. Activation of alpha- and beta-estrogen receptors by persistent pesticides in reporter cell lines. Life Sci 79 (2006) 1160-1169
12. Newbold R.R., Jefferson W.N., Padilla-Banks E., Walker V.R., and Pena D.S. Cell response endpoints enhance sensitivity of the immature mouse uterotropic assay. Reprod Toxicol 15 (2001) 245-252
13. Dalsenter P.R., Dallegrave E., Mello J.R.B., Langeloh A., Oliveira R.T., and Faqi A.S. Reproductive effects of endosulfan on male offspring of rats exposed during pregnancy and lactation. Hum Exp Toxicol 18 (1999) 583-589
14. Dalsenter P.R., de Araujo S.L., de Assis H.C., Andrade A.J., and Dallegrave E. Pre and postnatal exposure to endosulfan in Wistar rats. Hum Exp Toxicol 22 (2003) 171-175
15. Ashby J., Tinwell H., Odum J., and Lefevre P. Natural variability and the influence of concurrent control values on the detection and interpretation of low-dose or weak endocrine toxicities. Environ Health Perspect 112 (2004) 847-853
16. vom Saal F.S., and Welshons W.V. Large effects from small exposures. II. The importance of positive controls in low-dose research on bisphenol A. Environ Res 100 (2006) 50-76
17. Montes G.S., and Luque E.H. Effects of ovarian steroids on vaginal smears in the rat. Acta Anat (Basel) 133 (1988) 192-199
18. Varayoud J., Ramos J.G., Monje L., Bosquiazzo V., Muñoz-de-Toro M., and Luque E.H. The estrogen receptor alpha sigma3 mRNA splicing variant is differentially regulated by estrogen and progesterone in the rat uterus. J Endocrinol 186 (2005) 51-60
19. Monje L., Varayoud J., Luque E.H., and Ramos J.G. Neonatal exposure to bisphenol A modifies the abundance of estrogen receptor {alpha} transcripts with alternative 5′-untranslated regions in the female rat preoptic area. J Endocrinol 194 (2007) 201-212
20. Ramos J.G., Varayoud J., Sonnenschein C., Soto A.M., Munoz De Toro M., and Luque E.H. Prenatal exposure to low doses of bisphenol A alters the periductal stroma and glandular cell function in the rat ventral prostate. Biol Reprod 65 (2001) 1271-1277
21. Ramos J.G., Varayoud J., Bosquiazzo V.L., Luque E.H., and Muñoz-de-Toro M. Cellular turnover in the rat uterine cervix and its relationship to estrogen and progesterone receptor dynamics. Biol Reprod 67 (2002) 735-742
22. Castleman K.R. Digital image processing (1996), Prentice Hall Press, Englewood Cliffs, NJ
23. Vik D.P., Amiguet P., Moffat G.J., Fey M., Amiguet-Barras F., Wetsel R.A., and Tack B.F. Structural features of the human C3 gene: intron/exon organization, transcriptional start site, and promoter region sequence. Biochemistry 30 (1991) 1080-1085
24. vom Saal F.S., and Hughes C. An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment. Environ Health Perspect 113 (2005) 926-933
25. Durando M., Kass L., Piva J., Sonnenschein C., Soto A.M., Luque E.H., and Muñoz-de-Toro M. Prenatal bisphenol A exposure induces preneoplastic lesions in the mammary gland in Wistar rats. Environ Health Perspect 115 (2007) 80-86
26. Kilian E., Delport R., Bornman M.S., and Jager C. Simultaneous exposure to low concentrations of dichlorodiphenyltrichloroethane, deltamethrin, nonylphenol and phytoestrogens has negative effects on the reproductive parameters in male Spraque-Dawley rats. Andrologia 39 (2007) 128-135
27. Vandenberg L.N., Wadia P.R., Schaeberle C.M., Rubin B.S., Sonnenschein C., and Soto A.M. The mammary gland response to estradiol: monotonic at the cellular level, non-monotonic at the tissue-level of organization?. J Steroid Biochem Mol Biol 101 (2006) 263-274
28. Branham W.S., Zehr D.R., and Sheehan D.M. Differential sensitivity of rat uterine growth and epithelium hypertrophy to estrogens and antiestrogens. Proc Soc Exp Biol Med 203 (1993) 297-303
29. Buchanan D.L., Setiawan T., Lubahn D.B., Taylor J.A., Kurita T., Cunha G.R., and Cooke P.S. Tissue compartment-specific estrogen receptor-alpha participation in the mouse uterine epithelial secretory response. Endocrinology 140 (1999) 484-491
30. Barnes C.J., Vadlamudi R.K., and Kumar R. Novel estrogen receptor coregulators and signaling molecules in human diseases. Cell Mol Life Sci 61 (2004) 281-291
31. Cooper R.L., and Kavlock R.J. Endocrine disrupters and reproductive development: a weight-of-evidence overview. J Endocrinol 152 (1997) 159-166
32. Evans R.M. The steroid and thyroid hormone receptor superfamily. Science 240 (1988) 889-895
33. Mangelsdorf D.J., and Evans R.M. The RXR heterodimers and orphan receptors. Cell 83 (1995) 841-850
34. McKenna N.J., and O'Malley B.W. Combinatorial control of gene expression by nuclear receptors and coregulator. Cell 108 (2002) 465-474
35. Inoshita H., Masuyama H., and Hiramatsu Y. The different effects of endocrine-disrupting chemicals on estrogen receptor-mediated transcription through interaction with coactivator TRAP220 in uterine tissue. J Mol Endocrinol 31 (2003) 551-561
36. Fleming F.J., Hill A.D., McDermott E.W., O'Higgins N.J., and Young L.S. Differential recruitment of coregulator proteins steroid receptor coactivator-1 and silencing mediator for retinoid and thyroid receptors to the estrogen receptor-estrogen response element by beta-estradiol and 4-hydroxytamoxifen in human breast cancer. J Clin Endocrinol Metab 89 (2004) 375-383
37. Martini P.G., and Katzenellenbogen B.S. Modulation of estrogen receptor activity by selective coregulators. J Steroid Biochem Mol Biol 85 (2003) 117-122
38. Sasaki H., Hayakawa J., Terai Y., Kanemura M., Tanabe-Kimura A., Kamegai H., Seino-Noda H., Ezoe S., Matsumura I., Kanukura Y., Sakata M., Tasaka K., and Ohmichi M. Difference between genomic actions of estrogen versus raloxifene in human ovarian cancer cell lines. Oncogene 27 (2008) 2737-2745
39. Chang E.C., Charn T.H., Park S.H., Helferich W.G., Komm B., Katzenellenbogen J.A., and Katzenellenbogen B.S. Estrogen receptors alpha and beta as determinants of gene expression: influence of ligand, dose, and chromatin binding. Mol Endocrinol 22 (2008) 1032-1043
40. Hiremath M.B., and Kaliwal B.B. The anti-implantation action of endosulfan in albino mice: possible mechanisms. J Basic Clin Physiol Pharmacol 13 (2002) 329-340
41. Saxena S.P., Khare C., Farooq A., Murugesan K., Buckshee K., and Chandra J. DDT and its metabolites in leiomyomatous and normal human uterine tissue. Arch Toxicol 59 (1987) 453-455