Pig-MAP, porcine acute phase proteins and standardisation of assays in Europe

Comparative Clinical Pathology

Volumn 7, Issue 4, 1997, Pages 208-213

  Alava, María A ^a   Gonzalez Ramon N ^a   Heegaard, P ^b   Guzylack, S ^c   Toussaint, M J M ^d   Lipperheide, C ^e   Madec, F ^c   Grays, E ^d   Eckersall, P D ^f   Lampreave, F ^a   Pineiro A ^a  

^a UNIVERSITY OF ZARAGOZA   (Spain)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^c Healthy Pigs Production and Experimentation Section   (France)

^d UTRECHT UNIVERSITY   (Netherlands)

^e UNIVERSITY OF BONN   (Germany)

^f UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Acute phase proteins; Blood; Clinical chemistry; Immunoassays; Pig; Pig MAP; Standardisation

Indexed keywords

EID: 53249101628     PISSN: 16185641     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (28)

1. Berends, BR, Snijders JMA, van Logtestijn JG (1993) Efficacy of current EC meat inspection procedures and some proposed revisions with respect to microbiological safety: a critical review. Vet Rec 133:411-415
2. Burger W, Fennert EM, Pohle M et al. (1992) C-reactive protein - a characteristic feature of health control in swine. J Vet Med Ser A 39:635-638
3. Eckersall PD (1992) Meat inspection; the potential of acute phase protein assay. Meat Focus Int 1:279-283
4. Eckersall PD (1995) Acute phase proteins as markers of inflammatory lesions. Comp Haematol Int 5:93-97
5. 1-acid glycoprotein, ceruloplasmin, haptoglobin and C-reactive protein in the pig. Vet Immunol Immunopathol 51:377-385
6. Eckersall PD, Conner JG, Parton H (1989) An enzyme-linked immunosorbent assay for canine C-reactive protein. Vet Rec 124:490-491
7. Elbers ARW, Wisser IJR, Odink J et al. (1991) Changes in haematological and clinico-chemical profiles in blood of apparently healthy slaughter pigs, collected at the farm and at slaughter, in relation to the severity of pathological-anatomical lesions. Vet Quart 13:1-9.
8. Eurell TE, Bane DP, Hall WF et al. (1992) Serum haptoglobin concentration as an indicator of weight gain in pigs. Can J Vet Res 56:6-9
9. Francisco CJ, Shryock TR, Bane DP et al. (1996) Serum haptoglobin concentration in growing swine after intranasal challenge with Bordetella bronchiseptica and toxigenic Pasteurella multocida type D. Can J Vet Res 60:222-227
10. González-Ramón N, Alava MA, Sarsa JA et al. (1995) The major acute phase serum protein in pigs is homologous to human plasma kallikrein sensitive PK-120. FEBS Lett 371:227-230
11. Grays E, Obwolo MJ, Toussaint MJM (1994) Diagnostic significant of the major acute phase proteins in veterinary clinical chemistry: a review. Vet Bull 64:1009-1018
12. Hall WF, Eurell TE, Hansen RD et al. (1992) Serum haptoglobin concentration in swine naturally or experimentally infected with actinobacillus-pleuropneumoniae. J Am Vet Med Assoc 201:1730-1733
13. Hashimoto K, Tobe T, Sumiya J et al. (1996) Primary structure of the pig homologue of human IHRP: Inter-alpha-trypsin inhibitor family heavy chain-related protein. J Biochem Tokyo 119:577-584
14. Heegaard PMH, Klausen J, Nielsen JP et al. (1997) The porcine acute-phase response to infection with Actinobacillus pleuropneumoniae. Haptoglobin, C-reactive protein and major acute-phase protein are sensitive indicators of infection. Submitted.
15. Heinrich PC, Castell JV, Andus T (1990) Interleukin-6 and the acute phase response. Biochem J 265:621-636
16. Itoh H, Tamura K, Izumi M et al. (1992) The influence of age and health-status on the serum alpha-1- acid glycoprotein level of conventional and specific pathogen-free pigs. Can J Vet Res 57:74-78
17. Kuschner I (1982) The phenomenon of the acute phase response. Ann NY Acad Sci 389:39-49
18. Lampreave F, Piñeiro A (1982) Characterization of a new alpha-glycoprotein as the major serum component in later fetal and newborn pigs. Comp Biochem Physiol 72B:215-219
19. Lampreave F, Piñeiro A (1984) The major serum protein of fetal and newborn pigs: biochemical properties and identification as a fetal form of alpha-1-acid glycoprotein. Int J Biochem 16:47-53
20. Lampreave F, Piñeiro A (1992) Concentrations of major plasma proteins in serum and whole-tissue extracts of porcine fetuses during development. J Reprod Fert 95:441-449.
21. Lampreave F, González-Ramón N, Martínez-Ayensa S et al. (1994) Characterization of the acute phase serum protein response in pigs. Electrophoresis 15:672-676
22. Macintyre SS (1988) C-reactive Protein. Methods Enzymol 163:383-399
23. Nishimura H, Kakizaki I, Muta T et al. (1995) cDNA and deduced amino acid sequence of human PK-120, a plasma kallikrein-sensitive glycoprotein. FEBS Lett 357:207-211
24. Saguchi K, Tobe T, Hashimoto K et al. (1995) Cloning and characterization of cDNA of inter-alpha-trypsin inhibitor family heavy chain related protein, a novel human plasma glycoprotein. J Biochem Tokyo 117:14-18
25. Saini PK, Webert D (1991) Application of acute phase reactants during antemortem and postmortem mean inspection. J Am Vet Med Assoc 198:1898-1901
26. Schreiber G, Howlett G, Nagashima M et al. (1982) The acute phase response of plasma protein synthesis during experimental inflammation. J Biol Chem 257:10271-10277
27. Toussaint MJM, Van Ederen AM, Grays E (1995) Implication of clinical pathology in assessment of animal health and in animal production and meat inspection. Comp Haematol Int 5:149-157
28. Whicher JT, Westacott CI (1992) The acute phase response. In: Whicer JT, Evans SW (eds) Biochemistry of inflammation. Kluwer Academic, London, pp 243-271