Hypoglycaemic activity of marine cyanobacteria in alloxan induced diabetic rats

Pharmacologyonline

Volumn 2, Issue , 2008, Pages 704-714

  Senthilkumar, R ^a   John, S Ahmed ^b  

^a Dongguk University Ilsan Hospital   (South Korea)

^b JAMAL MOHAMED COLLEGE   (India)

Author keywords

Blood glucose; Diabetes mellitus; Hypoglycemic; Marine cyanobacteria; Spirulina platensis

Indexed keywords

ACID PHOSPHATASE; ALANINE AMINOTRANSFERASE; ALCOHOL; ALKALINE PHOSPHATASE; ALLOXAN; ANTIDIABETIC AGENT; ASPARTATE AMINOTRANSFERASE; CHOLESTEROL; CHROOCOCCUS MINOR EXTRACT; CYANOBACTERIA EXTRACT; GLUCOSE; GLYCOGEN; NATURAL PRODUCT; OSCILLATORIA CHALYBEA EXTRACT; PHORMIDIUM CORIUM EXTRACT; SPIRULINA LABRYNTHIFORMIS EXTRACT; SPIRULINA PLATENSIS EXTRACT; SYNCHOCYSTIS PEVALAKII EXTRACT; UNCLASSIFIED DRUG;

ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CHEMISTRY; CHOLESTEROL BLOOD LEVEL; CHROOCOCCUS MINOR; CONTROLLED STUDY; CYANOBACTERIUM; DIABETES MELLITUS; DRUG MECHANISM; ENZYME BLOOD LEVEL; EXPERIMENTAL RAT; GLUCOSE BLOOD LEVEL; GLYCOGEN LIVER LEVEL; HYPOGLYCEMIA; MALE; MARINE BACTERIUM; NONHUMAN; OSCILLATORIA CHALYBEA; PHORMIDIUM CORIUM; PHYTOCHEMISTRY; PROTEIN BLOOD LEVEL; RAT; SPIRULINA LABRYNTHIFORMIS; SPIRULINA PLATENSIS; SWISS WEBSTER MOUSE; SYNCHOCYSTIS PEVALAKII; TOXICITY TESTING; TREATMENT DURATION;

EID: 53249100504     PISSN: None     EISSN: 18278620     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Li, W.L., Zheng, H.C., Bukuru, J., Dekimbe, N., Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus. Journal of Ethanopharmocology, 2004; 92: 1-21.
2. Das, A.V., Padayutti, P.S., and Paulose, C.S., Effect of leaf extract of Aegle marmelose (L) Corra ex Roxb. On histological and ultrastructural changes in tissues of streptozotocin induced diabetic rats, Indian Journal of Experimental Biology, 1996; 14: 341-344.
3. Garcia, M.J., McNamara PM, Gordan, T, and Kannel, W.B., Morbidity and mortality in diabetics in the Framingham population. Sixteen year follow-up study. Diabetes, 1974; 23(2): 105-112.
4. Piedrola, G., Novo, E., Escobar, F., Garcia - Robles, R., White blood cell count and insulin resistance in patients with coronary artery disease. Annual Endocrinaology (Paris). 2001; 62: 7-10.
5. Goksel Gokce, Mehmet Zeki Haznedaroglu, Evaluation of antidiabetic, antioxidant and vasoprotective effects of Posidonia oceanica extract, Journal of Ethnopharm., 2008; 115: 122-130.
6. Tülay Bakirel, Utku Bakirel, Oya Ü stüner Keles, Sinem Günes, Ü Igen, Hasret Yardibi, In vivo assessment of antidiabetic and antioxidant activities of rosemary (Rosmarinus officinalis) in alloxan-diabetic rabbits, Journal of Ethno Pharm., 2008; 116: 64-73.
7. Kar, D.M., L. Maharana, S. Pattnaik and G.K. Dash, Studies on hypoglycemic activity of Solanum xannthocarpum Schard and Wen. Fruit Extract in Rats, 2006; 108: 251-256.
8. Gerwick, W.H., Mrozek, C., Moghaddam, M.F., and Agarwal, S.K., Novel cytotoxic peptides form the tropical marine cyanobacterium Hormothamnion enteromorphoides - Discovery, isolation and initial chemical and biological characterization of the hormothamnins from wild and cultured material. Experientia, 1989; 45: 115-121.
9. Dasikachary, T.V., Cyanophyta. Indian Council of Agricultural Research, New Delhi, (1959).
10. Rippka, R., Duruelles, J., Waterbury, J.B., Herdman, M., and Stanier, R.Y. Generic assignments, strain histories and properties of pure cultures of cyanobacteria. Jour. Gen. Microbiol. 1979; 111: 1-61.
11. Prince, P.S., Menon, V.P., Pari, L., Hypoglycemic activity of Syzigium cuminii seeds; effect on lipid peroxidation in alloxan diabetes rats, Journal of Ethanopharmacology, 1998; 61: 1-7.
12. Sazaki, T., Matsy, S., Sonace, A., Effect of aceticacid concentration on the colour reaction in the o-toluidine boric acid method for blood glucose estimation. Rinsho kagaku, 1972; 1: 346-353.
13. Lowry, O.H., Rosebrough, N.J., Farr, A.L., and Randall, R.J., Protein measurements with the Folin - phenol reagent. J. Biol. Chem. 1951; 193: 265-270.
14. Zak, B., Boyle, A.J., Zlatkis, A., A method for the determination of cholesterol. Journal of Clinical Medicine, 1953; 41: 486-492.
15. Seifter S, Dayton S, Movic B, Mutwzer E, The estimation of glycogen with the anthrone reagent. Arch. Biochem, 1985; 25: 191-201.
16. King, J., Determination of serum alkaline and acid phosphatase. In: Practical Clinical Enzymology. Dvan Nostrand, London (1959a).
17. King, E.J., 2,4, DNPH method of determination of serum GOT and serum GPT. Can. Med. Assoc. J, 1934; 31: 326.
18. Oberley, L.W., Free radicals and diabetes. Free radical Biology and medicine, 1988; 5: 113-124.
19. Soto CP, Muriel P, Reyes JL. Pancreatic lipidperooxidation in alloxan induced diabetes mellitus. Archieves olf Medical Research, 1994; 25 (4): 377-380.
20. Soto CP, Presz BL, Fayari LP, Reyes JL. Prevention of alloxan induced diabetes mellitus in the rat by silymarin. Compedium of Bichemistry and Physiology. Part C Pharmacology, Toxicology and Endocrinology, 1998; 119 (2): 125-129.
21. Mahmood vessal, Mina Hemmati, Mohamed Vasei. Antidiabetic effects of quercetin in streptozocin - induced diabetic rats. Comparative Biochemistry and Physiology, 2003; 135: 357-364.
22. nd edn.(WB Saunders Co., Philadaphia), (1958) 48.
23. Gitte S. Jensen, Donald I. Ginsberg, MS, Christian Drapeau MS, Blue-Green Algae as an Immuno-Enhancer and Biomodulator, JANA, 2001; 3 (4): 25-30.
24. Rodriguez - Hernandaz, A., Ble - Castillo. J.L., Juarez - Oropeza, M.A., Diaz - Zagoya, J.C., Spirulina maxima prevents fatty liver formation in CD - 1 male and female mice with experimental diabetes, 2001; 69: 1029-1037.
25. Sundararaman, M., Subramanian, G., Averzl, H.I., Akbarsha, M.A., Evaluation of the bioactivity of Marine cyanobacteria on some biochemical parameters of Rat serum. 1996; 10: 9-12.
26. Grover, J.K., Vats, V., Yadav, S., Effect of feeding aqueous extract of Petrocarpus marsupium on glycogen content of tissues and the key enzymes of carbohydrate metabolism. Molecular cellular Biochemists, 2002; 241: 53-59.
27. Maiti, R., Hana, D., Das, U.K., Ghose, D., Antidiabetic effect of aqueous of seed on Tamarindus indica in streptozotocin - induced diabetic rats. Joournal of Ethno Pharm., 2004; 92 (1): 85-91.
28. Khan, B.A., Abraham, A., Leclamma, S., Hypoglycemic action of Murray Koenigii (Curry leaf), Brassica junca (mustard); mechanism of action. Indian Journal of Biochem Biophys., 1995; 32: 106-108.
29. Torres - Duran, P.V., Miranda - Zamora, R., Paredes - Carbajal, M.C., Mascher, D., Ble - Castillo, J., Diaz zasgoya, J.C., Juarez - Oropeza, M.A., Studies on the preventive effect of Spirulina maxima on fatty liver development induced by carbon tetrachloride in the rat. Journal of Ethno Pharm., 1999; 64(2): 141-147.
30. Ble - Castillo, J.L., Rodriguez- Hernandez, A., Mirand - Zamora, R., Juarez, M.A., Diaz - Zagoya, J.C., Arthrospira maxima prevents the acute fattyliver induced by the administration of Simvastatin, ethanol and a hypercholesterolemic diet to mice. Life Science, 2002; 70(22): 2665-2673.