Total structure and biological properties of laxaphycins A and B, cyclic lipopeptides from the marine cyanobacterium Lyngbya majuscula

International Journal of Peptide Research and Therapeutics

Volumn 4, Issue 4-6, 1997, Pages 289-292

  Bonnard, Isabelle ^a   Rolland, Marc ^a   Francisco, Christian ^a   Banaigs, Bernard ^a  

^a UNIVERSITÉ DE PERPIGNAN   (France)

Author keywords

Antifungal; Cytotoxic; E didehydroaminobutyric acid; Marfey's reagent; Synergism; Aminodeca(octa)noic acids

Indexed keywords

EID: 53249096085     PISSN: 15733149     EISSN: 15733904     Source Type: Journal    
DOI: 10.1007/BF02442891     Document Type: Article

References (11)

1. Frankmölle, W.P., Knübel, G., Moore, R.E. and Patterson, G.M.L., J. Antibiotics, 45 (1992) 1458.
2. Marfey, P., Carlsberg Res. Commun., 49 (1984) 591.
3. Freidinger, R.M., Hinkle, J.S., Perlow, D.S. and Arison, B.H., J. Org. Chem., 48 (1983) 77.
4. Gerwick, W.H., Jiang, Z.D., Agarwal, S.K. and Farmer, B.T., Tetrahedron, 48 (1992) 2313.
5. Schöllkopf, U., Tetrahedron, 39 (1983) 2085.
6. Kato, T., Hinoo, H., Terui, Y., Kikushi, J. and Shoji, J., J. Antibiotics, 41 (1988) 719. The CD spectrum of Asp(3-OH) obtained from laxaphycin B hydrolysate gave a negative 216 nm Cotton effect which increased to positive numbers at 239 nm, a spectrum indicative of D-configuration; in comparison, the CD spectrum of L-threo-Asp(3-OH) in the reference mentioned above gave a positive 205 nm Cotton effect which decreased to negative numbers at 245 nm.
7. Beck, W.T., Mueller, T.J. and Tanzer, L.R., Cancer Res., 39 (1979) 2070.
8. Danks, M.K., Yalowich, J.C. and Beck, W.T., Cancer Res., 47 (1987) 1297.
9. Frankmölle, W.P., Larsen, L.K., Caplan, F.R., Patterson, G.M.L., Knübel, G., Levine, I.A. and Moore, R.E., J. Antibiotics, 45 (1992) 1451.
10. Gerwick, W.H., Mrozek, C., Moghaddam, M.F. and Agarwal, S.K., Experientia, 45 (1989) 115.
11. Maget-Dana, R., Thimon, L., Peypoux, F. and Ptak, M., Biochimie, 74 (1992) 1047.