Identification of protein C epitopes altered during its nanoencapsulation

Journal of Protein Chemistry

Volumn 18, Issue 7, 1999, Pages 779-784

  Chognot, D ^a   Zambaux, M F ^a   Bonneaux, F ^a   Gaussem, P ^b   Pittet, J L ^c   Aiach, M ^b   Vigneron, C ^a  

^a UNIVERSITÉ DE LORRAINE   (France)

^b INSERM   (France)

^c BIOMÉRIEUX   (France)

Author keywords

Anticoagulant activity; Methylene chloride; Monoclonal antibodies; Protein C; Ultrasonication

Indexed keywords

DICHLOROMETHANE; DRUG ANTIBODY; EPITOPE; NANOPARTICLE; PROTEIN C;

ANTICOAGULATION; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG IDENTIFICATION; ENCAPSULATION; PARTIAL THROMBOPLASTIN TIME; PROTEIN AGGREGATION; PROTEIN DEGRADATION; ULTRASOUND;

EID: 53149154543     PISSN: 02778033     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1020633602335     Document Type: Article

References (21)

1. Bauer, K. A., Kass, B. L., Beeler, D. L. and Rosenberg, R. D. (1984). J. Clin. Invest. 74, 2033-2041.
2. Clouse, L. H., and Comp, M. D. (1986). New Engl. J. Med. 314, 1298-1304.
3. Couvreur, P. (1985). Formes pharmaceutiques nouvelles: Aspects technologique, biopharmaceutique et médical, Lavoisier Tec. et Doc.
4. Dahlbäck, B. (1995). Thromb. Res. 77, 1-43.
5. Fisher, C. L., Greencard, J. S., and Griffin, J. H. (1994). Prot. Sci. 3, 588-599.
6. Gaspar, M. M., Blanco, D., Cruz, M. E. M., and Alonso, M. J. (1998). J. Control. Rel. 52, 53-62.
7. Grey, S. T., and Hancock, W. W. (1996). J. Immunol. 156, 2256-2263.
8. Guillin, M. C. (1987). La Presse Médicale. 16, 468-470.
9. Marlar, R. A., Kressin, D. D., and Madden, R. M. (1993). Thromb. Haemost. 69, 16-20.
10. Mather, T., Oganessyan, V., Hof, P., Huber, R., Foundling, S., Esmon, C., Bode, W. (1996). Embo J. 15, 6822-6831.
11. Mesters, R. M., Houghten, R. A., Griffin, J. H. (1991). J. Biol. Chem. 266, 24514-24519.
12. Niven, R. W., Ip, A. Y., Mittelman, S., Prestrelski, S. J., Arakawa, T. (1995). Pharm. Res. 12, 53-59.
13. Park, T. G., Lu, W., and Crotts, G. (1995). J. Control. Rel. 33, 211-222.
14. Stenflo, J. (1984). Semin. Thromb. Hemostas. 10, 109-121.
15. Vincenot, A., and Gaussem, P. (1997). Ann. Biol. Clin. 55, 17-24.
16. Vincenot, A., Gaussem, P., Pittet, J. L., Debost, S., and Aiach, M. (1995). FEBS Letters. 367, 153-157.
17. Vincenot, A., Pittet, J. L., Aiach, M., and Gaussem, P. (1998). FEBS Letters 432, 94-97.
18. Walker, F. J., and Fay, P. J. (1992). FASEB J. 6, 2561-2567.
19. Wiesel, M. L., Grunebaum, D., Freyssinet, J. M., and Cazenave, J. P. (1988). La Presse Médicale 17, 1333-1337.
20. Zambaux, M. F., Bonneaux, F., and Dellacherie, E. (1998). J. Prot. Chem. 17, 279-284.
21. Zambaux, M. F., Bonneaux, F., Gref, R., Dellacherie, E., and Vigneron, C. (1999). J. Control. Rel. in press.