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Volumn 68, Issue 11, 2008, Pages 4013-4017

Unraveling the mystery of erythropoietin-stimulating agents in cancer promotion

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DACARBAZINE; DAUNORUBICIN; ERYTHROPOIETIN; FLUOROURACIL; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; PLACEBO; RECOMBINANT ERYTHROPOIETIN; VINBLASTINE;

EID: 53149147478     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-3324     Document Type: Review
Times cited : (2)

References (42)
  • 1
    • 15944374753 scopus 로고    scopus 로고
    • Recombinant human erythropoietin and overall survival in cancer patients: Results of a comprehensive meta-analysis
    • Bohlius J, Langensiepen S, Schwarzer G, et al. Recombinant human erythropoietin and overall survival in cancer patients: results of a comprehensive meta-analysis. J Natl Cancer Inst 2005;97:489-98.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 489-498
    • Bohlius, J.1    Langensiepen, S.2    Schwarzer, G.3
  • 2
    • 0142186283 scopus 로고    scopus 로고
    • Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: Randomised, double-blind, placebo-controlled trial
    • Henke M, Laszig R, Rube C, et al. Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial. Lancet 2003;362:1255-60.
    • (2003) Lancet , vol.362 , pp. 1255-1260
    • Henke, M.1    Laszig, R.2    Rube, C.3
  • 3
    • 24944454286 scopus 로고    scopus 로고
    • Maintaining normal hemoglobin levels with epoetin alfa in mainly nonanemic patients with metastatic breast cancer receiving first-line chemotherapy: A survival study
    • Leyland-Jones B, Semiglazov V, Pawlicki M, et al. Maintaining normal hemoglobin levels with epoetin alfa in mainly nonanemic patients with metastatic breast cancer receiving first-line chemotherapy: a survival study. J Clin Oncol 2005;23:5960-72.
    • (2005) J Clin Oncol , vol.23 , pp. 5960-5972
    • Leyland-Jones, B.1    Semiglazov, V.2    Pawlicki, M.3
  • 4
    • 0041976976 scopus 로고    scopus 로고
    • Breast cancer trial with erythropoietin terminated unexpectedly
    • Leyland-Jones B. Breast cancer trial with erythropoietin terminated unexpectedly. Lancet Oncol 2003;4:459-60.
    • (2003) Lancet Oncol , vol.4 , pp. 459-460
    • Leyland-Jones, B.1
  • 5
    • 34047221511 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled trial of erythropoietin in non-small-cell lung cancer with disease-related anemia
    • Wright JR, Ung YC, Julian JA, et al. Randomized, double-blind, placebo-controlled trial of erythropoietin in non-small-cell lung cancer with disease-related anemia. J Clin Oncol 2007;25:1027-32.
    • (2007) J Clin Oncol , vol.25 , pp. 1027-1032
    • Wright, J.R.1    Ung, Y.C.2    Julian, J.A.3
  • 6
    • 40549088086 scopus 로고    scopus 로고
    • Randomized study of the importance of novel erythropoiesis stimulating protein (Aranesp®) for the effect of radiotherapy in patients with primary squamous cell carcinoma of the head and neck (HNSCC) - the Danish Head and Neck Cancer Group DAHANCA 10 randomized trial
    • Overgaard J, Hoff C, Sand Hansen H, et al. Randomized study of the importance of novel erythropoiesis stimulating protein (Aranesp®) for the effect of radiotherapy in patients with primary squamous cell carcinoma of the head and neck (HNSCC) - the Danish Head and Neck Cancer Group DAHANCA 10 randomized trial. Eur J Cancer Suppl 2007;5:7.
    • (2007) Eur J Cancer Suppl , vol.5 , pp. 7
    • Overgaard, J.1    Hoff, C.2    Sand Hansen, H.3
  • 7
    • 53149103166 scopus 로고    scopus 로고
    • http://www.fda.gov/ohrms/dockets/ac/07/briefing/2007-4301b2-00-index.htm.
  • 8
    • 53149086222 scopus 로고    scopus 로고
    • http://wwwext.amgen.com/media/media_pr_detail.jsp?year= 2007&releaseID=1083091.
  • 9
    • 38649128164 scopus 로고    scopus 로고
    • Phase III trial to evaluate the efficacy of maintaining hemoglobin levels above 12.0 g/dL with erythropoietin vs above 10.0 g/dL without erythropoietin in anemic patients receiving concurrent radiation and cisplatin for cervical cancer
    • Thomas G, Ali S, Hoebers FJP, et al. Phase III trial to evaluate the efficacy of maintaining hemoglobin levels above 12.0 g/dL with erythropoietin vs above 10.0 g/dL without erythropoietin in anemic patients receiving concurrent radiation and cisplatin for cervical cancer. Gynecol Oncol 2008;108:317-25.
    • (2008) Gynecol Oncol , vol.108 , pp. 317-325
    • Thomas, G.1    Ali, S.2    Hoebers, F.J.P.3
  • 10
    • 33646905411 scopus 로고    scopus 로고
    • Recombinant human erythropoietins and cancer patients: Updated meta-analysis of 57 studies including 9353 patients
    • Bohlius J, Wilson J, Seidenfeld J, et al. Recombinant human erythropoietins and cancer patients: updated meta-analysis of 57 studies including 9353 patients. J Natl Cancer Inst 2006;98:708-14.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 708-714
    • Bohlius, J.1    Wilson, J.2    Seidenfeld, J.3
  • 11
    • 33750983605 scopus 로고    scopus 로고
    • Correction of anemia with epoetin alfa in chronic kidney disease
    • Singh AK, Szczech L, Tang KL, et al. Correction of anemia with epoetin alfa in chronic kidney disease. N Engl J Med 2006;355:2085-98.
    • (2006) N Engl J Med , vol.355 , pp. 2085-2098
    • Singh, A.K.1    Szczech, L.2    Tang, K.L.3
  • 12
    • 34548094540 scopus 로고    scopus 로고
    • Erythropoietin and erythropoietin receptor coexpression is associated with poor survival in stage I non-small cell lung cancer
    • Saintigny P, Besse B, Callard P, et al. Erythropoietin and erythropoietin receptor coexpression is associated with poor survival in stage I non-small cell lung cancer. Clin Cancer Res 2007;13:4825-31.
    • (2007) Clin Cancer Res , vol.13 , pp. 4825-4831
    • Saintigny, P.1    Besse, B.2    Callard, P.3
  • 13
    • 21744451644 scopus 로고    scopus 로고
    • Erythropoietin-mediated activation of JAK-STAT signaling contributes to cellular invasion in head and neck squamous cell carcinoma
    • Lai SY, Childs EE, Xi S, et al. Erythropoietin-mediated activation of JAK-STAT signaling contributes to cellular invasion in head and neck squamous cell carcinoma. Oncogene 2005;24:4442-9.
    • (2005) Oncogene , vol.24 , pp. 4442-4449
    • Lai, S.Y.1    Childs, E.E.2    Xi, S.3
  • 14
    • 0035328802 scopus 로고    scopus 로고
    • Erythropoietin and erythropoietin receptor expression in human cancer
    • Acs G, Acs P, Beckwith SM, et al. Erythropoietin and erythropoietin receptor expression in human cancer. Cancer Res 2001;61:3561-5.
    • (2001) Cancer Res , vol.61 , pp. 3561-3565
    • Acs, G.1    Acs, P.2    Beckwith, S.M.3
  • 15
    • 0037767746 scopus 로고    scopus 로고
    • Expression of erythropoietin receptor splice variants in human cancer
    • Arcasoy MO, Jiang X, Haroon ZA. Expression of erythropoietin receptor splice variants in human cancer. Biochem Biophys Res Commun 2003;307:999-1007.
    • (2003) Biochem Biophys Res Commun , vol.307 , pp. 999-1007
    • Arcasoy, M.O.1    Jiang, X.2    Haroon, Z.A.3
  • 17
    • 0032566597 scopus 로고    scopus 로고
    • Estrogen-dependent production of erythropoietin in uterus and its implication in uterine angiogenesis
    • Yasuda Y, Masuda S, Chikuma M, Inoue K, Nagao M, Sasaki R. Estrogen-dependent production of erythropoietin in uterus and its implication in uterine angiogenesis. J Biol Chem 1998;273:25381-7.
    • (1998) J Biol Chem , vol.273 , pp. 25381-25387
    • Yasuda, Y.1    Masuda, S.2    Chikuma, M.3    Inoue, K.4    Nagao, M.5    Sasaki, R.6
  • 18
    • 20344380430 scopus 로고    scopus 로고
    • Erythropoietin signaling promotes invasiveness of human head and neck squamous cell carcinoma
    • Mohyeldin A, Lu H, Dalgard C, et al. Erythropoietin signaling promotes invasiveness of human head and neck squamous cell carcinoma. Neoplasia 2005;7:537-43.
    • (2005) Neoplasia , vol.7 , pp. 537-543
    • Mohyeldin, A.1    Lu, H.2    Dalgard, C.3
  • 19
    • 33746224221 scopus 로고    scopus 로고
    • Erythropoietin activates the phosphoinositide 3-kinase/Akt pathway in human melanoma cells
    • Kumar SM, Yu H, Fong D, Acs G, Xu X. Erythropoietin activates the phosphoinositide 3-kinase/Akt pathway in human melanoma cells. Melanoma Res 2006;16:275-83.
    • (2006) Melanoma Res , vol.16 , pp. 275-283
    • Kumar, S.M.1    Yu, H.2    Fong, D.3    Acs, G.4    Xu, X.5
  • 20
    • 28244458421 scopus 로고    scopus 로고
    • Erythropoietin promotes MCF-7 breast cancer cell migration by an ERK/mitogen-activated protein kinase-dependent pathway and is primarily responsible for the increase in migration observed in hypoxia
    • Lester RD, Jo M, Campana WM, G onias SL. Erythropoietin promotes MCF-7 breast cancer cell migration by an ERK/mitogen-activated protein kinase-dependent pathway and is primarily responsible for the increase in migration observed in hypoxia. J Biol Chem 2005;280:39273-7.
    • (2005) J Biol Chem , vol.280 , pp. 39273-39277
    • Lester, R.D.1    Jo, M.2    Campana, W.M.3    onias SL, G.4
  • 22
    • 0038751965 scopus 로고    scopus 로고
    • Hypoxia-inducible erythropoietin signaling in squamous dysplasia and squamous cell carcinoma of the uterine cervix and its potential role in cervical carcinogenesis and tumor progression
    • Acs G, Zhang PJ, McGrath CM, et al. Hypoxia-inducible erythropoietin signaling in squamous dysplasia and squamous cell carcinoma of the uterine cervix and its potential role in cervical carcinogenesis and tumor progression. Am J Pathol 2003;162:1789-806.
    • (2003) Am J Pathol , vol.162 , pp. 1789-1806
    • Acs, G.1    Zhang, P.J.2    McGrath, C.M.3
  • 24
    • 33645341754 scopus 로고    scopus 로고
    • EPO receptor transcription is not elevated nor predictive of surface expression in human tumor cells [abstract 5457]
    • Sinclair A, Busse L, Rogers N, et al. EPO receptor transcription is not elevated nor predictive of surface expression in human tumor cells [abstract 5457]. Proc Am Assoc Cancer Res 2005;46:1287.
    • (2005) Proc Am Assoc Cancer Res , vol.46 , pp. 1287
    • Sinclair, A.1    Busse, L.2    Rogers, N.3
  • 25
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
    • James C, Ugo V, Le Couedic JP, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005;434:1144-8.
    • (2005) Nature , vol.434 , pp. 1144-1148
    • James, C.1    Ugo, V.2    Le Couedic, J.P.3
  • 26
    • 0034910717 scopus 로고    scopus 로고
    • Activation of the transcription factor NF-κB by the erythropoietin receptor: Structural requirements and biological significance
    • Bittorf T, Buchse T, Sasse T, Jaster R, Brock J. Activation of the transcription factor NF-κB by the erythropoietin receptor: structural requirements and biological significance. Cell Signal 2001;13:673-81.
    • (2001) Cell Signal , vol.13 , pp. 673-681
    • Bittorf, T.1    Buchse, T.2    Sasse, T.3    Jaster, R.4    Brock, J.5
  • 27
    • 33750588816 scopus 로고    scopus 로고
    • Do erythropoietin receptors on cancer cells explain unexpected clinical findings?
    • Henke M, Mattern D, Pepe M, et al. Do erythropoietin receptors on cancer cells explain unexpected clinical findings? J Clin Oncol 2006;24:4708-13.
    • (2006) J Clin Oncol , vol.24 , pp. 4708-4713
    • Henke, M.1    Mattern, D.2    Pepe, M.3
  • 28
    • 33947696124 scopus 로고    scopus 로고
    • Erythropoietin/erythropoietin- receptor system is involved in angiogenesis in human hepatocellular carcinoma
    • Ribatti D, Marzullo A, Gentile A, et al. Erythropoietin/erythropoietin- receptor system is involved in angiogenesis in human hepatocellular carcinoma. Histopathol 2007;50:591-6.
    • (2007) Histopathol , vol.50 , pp. 591-596
    • Ribatti, D.1    Marzullo, A.2    Gentile, A.3
  • 29
    • 33947711717 scopus 로고    scopus 로고
    • Erythropoietin/erythropoietin receptor system is involved in angiogenesis in human neuroblastoma
    • Ribatti D, Poliani PL, Longo V, Mangieri D, Nico B, Vacca A. Erythropoietin/erythropoietin receptor system is involved in angiogenesis in human neuroblastoma. Histopathol 2007;50:636-41.
    • (2007) Histopathol , vol.50 , pp. 636-641
    • Ribatti, D.1    Poliani, P.L.2    Longo, V.3    Mangieri, D.4    Nico, B.5    Vacca, A.6
  • 30
    • 34547120946 scopus 로고    scopus 로고
    • Expression and function of erythropoietin receptors in tumors: Implications for the use of erythropoiesis-stimulating agents in cancer patients
    • Sinclair AM, Todd MD, Forsythe K, Knox SJ, Elliott S, Begley CG. Expression and function of erythropoietin receptors in tumors: implications for the use of erythropoiesis-stimulating agents in cancer patients. Cancer 2007;110:477-88.
    • (2007) Cancer , vol.110 , pp. 477-488
    • Sinclair, A.M.1    Todd, M.D.2    Forsythe, K.3    Knox, S.J.4    Elliott, S.5    Begley, C.G.6
  • 31
    • 0036269105 scopus 로고    scopus 로고
    • Erythropoietin and G-CSF receptors in human tumor cells: Expression and aspects regarding functionality
    • Westphal G, Niederberger E, Blum C, et al. Erythropoietin and G-CSF receptors in human tumor cells: expression and aspects regarding functionality. Tumori 2002;88:150-9.
    • (2002) Tumori , vol.88 , pp. 150-159
    • Westphal, G.1    Niederberger, E.2    Blum, C.3
  • 32
    • 0033773958 scopus 로고    scopus 로고
    • Erythropoietin receptor expression in human melanoma cells
    • Selzer E, Wacheck V, Kodym R, et al. Erythropoietin receptor expression in human melanoma cells. Melanoma Res 2000;10:421-6.
    • (2000) Melanoma Res , vol.10 , pp. 421-426
    • Selzer, E.1    Wacheck, V.2    Kodym, R.3
  • 33
    • 0025848312 scopus 로고
    • Studies on the role of recombinant human erythropoietin in the growth regulation of human nonhematopoietic tumor cells in vitro
    • Berdel WE, Oberberg D, Reufi B, Thiel E. Studies on the role of recombinant human erythropoietin in the growth regulation of human nonhematopoietic tumor cells in vitro. Ann Hematol 1991;63:5-8.
    • (1991) Ann Hematol , vol.63 , pp. 5-8
    • Berdel, W.E.1    Oberberg, D.2    Reufi, B.3    Thiel, E.4
  • 34
    • 34948851821 scopus 로고    scopus 로고
    • Heat shock protein 70, erythropoietin, and cancer
    • author reply -7
    • Sizer KC. Heat shock protein 70, erythropoietin, and cancer. J Clin Oncol 2007;25:4326; author reply -7.
    • (2007) J Clin Oncol , vol.25 , pp. 4326
    • Sizer, K.C.1
  • 35
    • 12344335676 scopus 로고    scopus 로고
    • Erythropoietin induces cancer cell resistance to ionizing radiation and to cisplatin
    • Belenkov AI, Shenouda G, Rizhevskaya E, et al. Erythropoietin induces cancer cell resistance to ionizing radiation and to cisplatin. Mol Cancer Ther 2004;3:1525-32.
    • (2004) Mol Cancer Ther , vol.3 , pp. 1525-1532
    • Belenkov, A.I.1    Shenouda, G.2    Rizhevskaya, E.3
  • 37
    • 13444253909 scopus 로고    scopus 로고
    • Chemosensitization by erythropoietin through inhibition of the NF-κB rescue pathway
    • Carvalho G, Lefaucheur C, Cherbonnier C, et al. Chemosensitization by erythropoietin through inhibition of the NF-κB rescue pathway. Oncogene 2005;24:737-45.
    • (2005) Oncogene , vol.24 , pp. 737-745
    • Carvalho, G.1    Lefaucheur, C.2    Cherbonnier, C.3
  • 38
    • 23844507094 scopus 로고    scopus 로고
    • Recombinant human erythropoietin a targets intratumoral blood vessels, improving chemotherapy in human xenograft models
    • Tovari J, Gilly R, Raso E, et al. Recombinant human erythropoietin a targets intratumoral blood vessels, improving chemotherapy in human xenograft models. Cancer Res 2005;65:7186-93.
    • (2005) Cancer Res , vol.65 , pp. 7186-7193
    • Tovari, J.1    Gilly, R.2    Raso, E.3
  • 39
    • 36348966705 scopus 로고    scopus 로고
    • Cellular protection by erythropoietin: New therapeutic implications?
    • Joyeux-Faure M. Cellular protection by erythropoietin: new therapeutic implications? J Pharmacol Exp Ther 2007;323:759-62.
    • (2007) J Pharmacol Exp Ther , vol.323 , pp. 759-762
    • Joyeux-Faure, M.1
  • 40
    • 6944237300 scopus 로고    scopus 로고
    • Erythropoietin mediates tissue protection through an erythropoietin and common h-subunit heteroreceptor
    • Brines M, Grasso G, Fiordaliso F, et al. Erythropoietin mediates tissue protection through an erythropoietin and common h-subunit heteroreceptor. Proc Natl Acad Sci U S A 2004;101:14907-12.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 14907-14912
    • Brines, M.1    Grasso, G.2    Fiordaliso, F.3
  • 41
    • 34250349152 scopus 로고    scopus 로고
    • Weighing the hazards of erythropoiesis stimulation in patients with cancer
    • Khuri FR. Weighing the hazards of erythropoiesis stimulation in patients with cancer. N Engl J Med 2007;356:2445-8.
    • (2007) N Engl J Med , vol.356 , pp. 2445-2448
    • Khuri, F.R.1
  • 42
    • 38049174952 scopus 로고    scopus 로고
    • American Society of Hematology/American Society of Clinical Oncology 2007 clinical practice guideline update on the use of epoetin and darbepoetin
    • Rizzo JD, Somerfield MR, Hagerty KL, et al. American Society of Hematology/American Society of Clinical Oncology 2007 clinical practice guideline update on the use of epoetin and darbepoetin. Blood 2008;111:25-41.
    • (2008) Blood , vol.111 , pp. 25-41
    • Rizzo, J.D.1    Somerfield, M.R.2    Hagerty, K.L.3


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