Prolonged B-cell depletion following rituximab therapy in systemic lupus erythematosus: a report of two cases

Annals of the Rheumatic Diseases

Volumn 67, Issue 10, 2008, Pages 1493-1494

  Lu, T Y T ^a   Jonsdottir, T ^b   Van Vollenhoven, R F ^b   Isenberg, D A ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CD19 ANTIGEN; CYCLOPHOSPHAMIDE; HYDROXYCHLOROQUINE; IMMUNOSUPPRESSIVE AGENT; PREDNISOLONE; RIBONUCLEOPROTEIN ANTIBODY; RITUXIMAB; RO ANTIBODY;

ADULT; B LYMPHOCYTE; CASE REPORT; DRUG EFFECT; DRUG TREATMENT FAILURE; FEMALE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LETTER; LOW DRUG DOSE; LYMPHOCYTE DEPLETION; PRIORITY JOURNAL; SINUSITIS; SYSTEMIC LUPUS ERYTHEMATOSUS; TREATMENT DURATION; TREATMENT RESPONSE;

ADULT; ANTIBODIES, MONOCLONAL; B-LYMPHOCYTES; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTE COUNT; LYMPHOCYTE DEPLETION; TIME FACTORS;

EID: 53149133917     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.2008.091124     Document Type: Letter

References (5)

1. Ng KP, Leandro MJ, Edwards JC, Ehrenstein MR, Cambridge G, Isenberg DA. Repeated B cell depletion in the treatment of refractory systemic lupus eythematosus. Ann Rheum Dis 2006;65:942-5.
2. Jonsdottir T, Gunnarsson I, Risselada A, Weir Henriksson E, Klareskog L. van Vollenhoven RF. Treatment of refractory SLE with rituximab plus cyclophosphamide: cinical effects, serological changes, and predictors of response. Am Rheum Dis 2008;87:330-4.
3. Kimby E, Tolerability and safety of rituximab. Cancer Treat Rev 2005;31:456-73.
4. Solal-Celigny P, Safety of rituximab maintenance therapy in follicular rymphomas. Leuk Res 2006;30(Suppl 1):S16-21.
5. Anolik JH, Barnard J, Owen T, Zheng B, Kemshetti S, Looney RJ, et al. Delayed memory B cell recovery in peripheral blood and rymphoid tissue in systemic lupus erythematosus after B cell depletion therapy. Arthritis Rheum 2007;56:3044-56.