A novel rabbit model for studying RPE transplantation

Investigative Ophthalmology and Visual Science

Volumn 49, Issue 9, 2008, Pages 4115-4125

  Cong, Lidan ^a   Sun, Dawei ^a   Zhang, Zhongyu ^a   Jiao, Wanqiu ^a   Rizzolo, Lawrence J ^b   Peng, Shaomin ^a,b  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYFLUORESCEIN DIACETATE SUCCINIMIDYL ESTER; CYTOKERATIN; PROTEIN S 100; PROTEIN ZO1; EYE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD RETINA BARRIER; CELL LABELING; CELL TRANSPLANTATION; CHOROID; COCULTURE; CONJUNCTIVA; CONTROLLED STUDY; ELECTRIC RESISTANCE; ELECTROPHYSIOLOGY; EXPERIMENTAL RABBIT; EYE FUNDUS; EYE PHOTOGRAPHY; FLUORESCENCE MICROSCOPY; HISTOCHEMISTRY; HUMAN; HUMAN CELL; IN VIVO STUDY; INCUBATION TEMPERATURE; INCUBATION TIME; NEWBORN; NONHUMAN; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; RETINA; RETINA ANGIOGRAPHY; RETINA BLOOD VESSEL; RETINA PIGMENT EPITHELIUM CELL TRANSPLANTATION; SCANNING LASER OPHTHALMOSCOPY; SCAR FORMATION; SCLEROTOMY; TIGHT JUNCTION; TISSUE FLAP; TISSUE STRUCTURE; ANIMAL; ANIMAL MODEL; CELL DIFFERENTIATION; CELL DIVISION; CYTOLOGY; ENUCLEATION; FEMALE; FLOW CYTOMETRY; GENETIC MARKER; GENETICS; METABOLISM; PIGMENT EPITHELIUM; PREGNANCY; RABBIT; TRANSPLANTATION;

ANIMALS; ANIMALS, NEWBORN; CELL DIFFERENTIATION; CELL DIVISION; EYE ENUCLEATION; EYE PROTEINS; FEMALE; FLOW CYTOMETRY; GENETIC MARKERS; MODELS, ANIMAL; PIGMENT EPITHELIUM OF EYE; PREGNANCY; RABBITS;

EID: 53149118225     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.08-1976     Document Type: Article

References (60)

1. West SK. Looking forward to 20/20: a focus on the epidemiology of eye diseases. Epidemiol Rev. 2000;22:64-70.
2. Aramant RB, Seiler MJ, Ball SL. Successful cotransplantation of intact sheets of fetal retina with retinal pigment epithelium. Invest Ophthalmol Vis Sci. 1999;40:1557-1564.
3. Crafoord S, Algvere PV, Kopp ED, Seregard S. Cyclosporine treatment of RPE allografts in the rabbit subretinal space. Acta Ophthalmol Scand. 2000;78:122-129. (Pubitemid 30201416)
4. Gouras P, Flood MT, Kjedbye H, Bilek MK, Eggers H. Transplantation of cultured human retinal epithelium to Bruch's membrane of the owl monkey's eye. Curr Eye Res. 1985;4:253-265. (Pubitemid 15117490)
5. Lane C, Boulton M, Marshall J. Transplantation of retinal pigment epithelium using a pars plana approach. Eye. 1989;3:27-32. (Pubitemid 19092079)
6. Li L, Turner JE. Optimal conditions for long-term photoreceptor cell rescue in RCS rats: the necessity for healthy RPE transplants. Exp Eye Res. 1991;52:669-679.
7. Li LX, Turner JE. Inherited retinal dystrophy in the RCS rat: prevention of photoreceptor degeneration by pigment epithelial cell transplantation. Exp Eye Res. 1988;47:911-917.
8. Little CW, Castillo B, DiLoreto DA, et al. Transplantation of human fetal retinal pigment epithelium rescues photoreceptor cells from degeneration in the Royal College of Surgeons rat retina. Invest Ophthalmol Vis Sci. 1996;37:204-211. (Pubitemid 26036532)
9. Little CW, Cox C, Wyatt J, del Cerro C, del Cerro M. Correlates of photoreceptor rescue by transplantation of human fetal RPE in the RCS rat. Exp Neurol. 1998;149:151-160. (Pubitemid 28091024)
10. Lopez R, Gouras P, Kjeldbye H, et al. Transplanted retinal pigment epithelium modifies the retinal degeneration in the RCS rat. Invest Ophthalmol Vis Sci. 1989;30:586-588. (Pubitemid 19100692)
11. Seaton AD, Sheedlo HJ, Turner JE. A primary role for RPE transplants in the inhibition and regression of neovascularization in the RCS rat. Invest Ophthalmol Vis Sci. 1994;35:162-169.
12. Algvere PV, Berglin L, Gouras P, Sheng Y, Kopp ED. Transplantation of RPE in age-related macular degeneration: observations in disciform lesions and dry RPE atrophy. Graefes Arch Clin Exp Ophthalmol. 1997;235:149-158.
13. Binder S, Stanzel BV, Krebs I, Glittenberg C. Transplantation of the RPE in AMD. Prog Retin Eye Res. 2007;26:516-554.
14. da Cruz L, Chen FK, Ahmado A, Greenwood J, Coffey P. RPE transplantation and its role in retinal disease. Prog Retin Eye Res. 2007;26:598-635. (Pubitemid 47615562)
15. Braun M, Kage A, Heimann K, Schraermeyer U. Retinal pigment epithelial cells from Royal College of Surgeons dystrophic rats can take up melanin granules. Graefes Arch Clin Exp Ophthalmol. 1999;237:67-71. (Pubitemid 29134868)
16. Crafoord S, Algvere PV, Seregard S, Kopp ED. Long-term outcome of RPE allografts to the subretinal space of rabbits. Acta Ophthalmol Scand. 1999;77:247-254.
17. Ye J, Wang HM, Ogden TE, Ryan SJ. Allotransplantation of rabbit retinal pigment epithelial cells double-labelled with 5-bromodeoxyuridine (BrdU) and natural pigment. Curr Eye Res. 1993;12:629-639. (Pubitemid 23238691)
18. Lund RD, Kwan AS, Keegan DJ, Sauve Y, Coffey PJ, Lawrence JM. Cell transplantation as a treatment for retinal disease. Prog Retin Eye Res. 2001;20:415-449. (Pubitemid 32523894)
19. Shiragami C, Matsuo T, Shiraga F, Matsuo N. Transplanted and repopulated retinal pigment epithelial cells on damaged Bruch's membrane in rabbits. Br J Ophthalmol. 1998;82:1056-1062. (Pubitemid 28451279)
20. Dunn KC, Aotaki-Keen AE, Putkey FR, Hjelmeland LM. ARPE-19, a human retinal pigment epithelial cell line with differentiated properties. Exp Eye Res. 1996;62:155-169. (Pubitemid 26140102)
21. Gabrielian K, Oganesian A, Patel SC, Verp MS, Ernest JT. Cellular response in rabbit eyes after human fetal RPE cell transplantation. Graefes Arch Clin Exp Ophthalmol. 1999;237:326-335. (Pubitemid 29145811)
22. Gouras P, Algvere P. Retinal cell transplantation in the macula: new techniques. Vision Res. 1996;36:4121-4125. (Pubitemid 26421769)
23. Jiang LQ, Jorquera M, Streilein JW, Ishioka M. Unconventional rejection of neural retinal allografts implanted into the immunologically privileged site of the eye. Transplantation. 1995;59:1201-1207.
24. Zhang X, Bok D. Transplantation of retinal pigment epithelial cells and immune response in the subretinal space. Invest Ophthalmol Vis Sci. 1998;39:1021-1027. (Pubitemid 28196688)
25. Gouras P, Lopez R, Brittis M, Kjeldbye H. The ultrastructure of transplanted rabbit retinal epithelium. Graefes Arch Clin Exp Ophthalmol. 1992;230:468-475.
26. Lai CC, Gouras P, Doi K, et al. Tracking RPE transplants labeled by retroviral gene transfer with green fluorescent protein. Invest Ophthalmol Vis Sci. 1999;40:2141-2146. (Pubitemid 29365180)
27. Morstyn G, Pyke K, Gardner J, Ashcroft R, de Fazio A, Bhathal P. Immunohistochemical identification of proliferating cells in organ culture using bromodeoxyuridine and a monoclonal antibody. J Histochem Cytochem. 1986;34:697-701. (Pubitemid 16073400)
28. Dumitriu IE, Mohr W, Kolowos W, Kern P, Kalden JR, Herrmann M. 5,6-carboxyfluorescein diacetate succinimidyl ester-labeled apoptotic and necrotic as well as detergent-treated cells can be traced in composite cell samples. Anal Biochem. 2001;299:247-252. (Pubitemid 34053417)
29. Paramore CG, Turner DA, Madison RD. Fluorescent labeling of dissociated fetal cells for tissue culture. J Neurosci Methods. 1992;44:7-17.
30. Weston SA, Parish CR. New fluorescent dyes for lymphocyte migration studies: analysis by flow cytometry and fluorescence microscopy. J Immunol Methods. 1990;133:87-97.
31. Fujioka H, Hunt PJ, Rozga J, et al. Carboxyfluorescein (CFSE) labelling of hepatocytes for short-term localization following intraportal transplantation. Cell Transplant. 1994;3:397-408. (Pubitemid 24286982)
32. Hasbold J, Gett AV, Rush JS, et al. Quantitative analysis of lymphocyte differentiation and proliferation in vitro using carboxyfluorescein diacetate succinimidyl ester. Immunol Cell Biol. 1999;77:516-522
33. Groszer M, Erickson R, Scripture-Adams DD, et al. Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo. Science. 2001;294:2186-2189. (Pubitemid 33150679)
34. Gruber HE, Leslie KP, Ingram JA, Hanley EN, Jr. Optimization of 5-(and-6)-carboxyfluorescein diacetate succinimidyl ester for labeling human intervertebral disc cells in vitro. Biotech Histochem. 2000;75:118-123.
35. Li X, Dancausse H, Grijalva I, Oliveira M, Levi AD. Labeling Schwann cells with CFSE-an in vitro and in vivo study. J Neurosci Methods. 2003;125:83-91. (Pubitemid 36579336)
36. Del Priore LV, Tezel TH, Kaplan HJ. Survival of allogeneic porcine retinal pigment epithelial sheets after subretinal transplantation. Invest Ophthalmol Vis Sci. 2004;45:985-992.
37. Luo Y, Zhuo Y, Fukuhara M, Rizzolo LJ. Effects of culture conditions on heterogeneity and the apical junctional complex of the ARPE-19 cell line. Invest Ophthalmol Vis Sci. 2006;47:3644-3655. (Pubitemid 351639734)
38. Peng S, Rahner C, Rizzolo LJ. Apical and basal regulation of the permeability of the retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2003;44:808-817. (Pubitemid 36159733)
39. Gonzalez-Mariscal L, Chavez de Ramirez B, Cereijido M. Effect of temperature on the occluding junctions of monolayers of epithelioid cells (MDCK). J Membr Biol. 1984;79:175-184. (Pubitemid 14114448)
40. Hunt RC, Dewey A, Davis AA. Transferrin receptors on the surfaces of retinal pigment epithelial cells are associated with the cytoskeleton. J Cell Sci. 1989;92:655-666.
41. Hu DN, Ritch R, McCormick SA, Pelton-Henrion K. Isolation and cultivation of human iris pigment epithelium. Invest Ophthalmol Vis Sci. 1992;33:2443-2453.
42. Hollborn M, Kohen L, Wiedemann P, Enzmann V. The influence of pro-inflammatory cytokines on human retinal pigment epithelium cell receptors. Graefes Arch Clin Exp Ophthalmol. 2001;239:294-301. (Pubitemid 32514997)
43. McKechnie NM, Boulton M, Robey HL, Savage FJ, Grierson I. The cytoskeletal elements of human retinal pigment epithelium: in vitro and in vivo. J Cell Sci. 1988;91:303-312.
44. Thumann G, Bartz-Schmidt KU, El Bakri H, et al. Transplantation of autologous iris pigment epithelium to the subretinal space in rabbits. Transplantation. 1999;68:195-201. (Pubitemid 29360276)
45. Rizzolo LJ. Development and role of tight junctions in the retinal pigment epithelium. Int Rev Cytol. 2007;258:195-234.
46. Ban Y, Rizzolo LJ. A culture model of development reveals multiple properties of RPE tight junctions. Mol Vis. 1997;3:18.
47. Rahner C, Fukuhara M, Peng S, Kojima S, Rizzolo LJ. The apical and basal environments of the retinal pigment epithelium regulate the maturation of tight junctions during development. J Cell Sci. 2004;117:3307-3318. (Pubitemid 39139915)
48. Chang CW, Roque RS, Defoe DM, Caldwell RB. An improved method for isolation and culture of pigment epithelial cells from rat retina. Curr Eye Res. 1991;10:1081-1086.
49. Gamm DM, Melvan JN, Shearer RL, et al. A novel serum-free method for culturing human prenatal retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 2008;49:788-799.
50. Hu J, Bok D. A cell culture medium that supports the differentiation of human retinal pigment epithelium into functionally polarized monolayers. Mol Vis. 2001;7:14-19. (Pubitemid 36153646)
51. Maminishkis A, Chen S, Jalickee S, et al. Confluent monolayers of cultured human fetal retinal pigment epithelium exhibit morphology and physiology of native tissue. Invest Ophthalmol Vis Sci. 2006;47:3612-3624. (Pubitemid 351639731)
52. Hu JG, Gallemore RP, Bok D, Lee AY, Frambach DA. Localization of NaK ATPase on cultured human retinal pigment epithelium. Invest Ophthalmol Vis Sci. 1994;35:3582-3588. (Pubitemid 24337971)
53. Gallemore RP, Hughes BA, Miller SS. Retinal pigment epithelial transport mechanisms and their contributions to the electroretinogram. Prog Retin Eye Res. 1997;16:509-566. (Pubitemid 27361766)
54. Wang H, Leonard DS, Castellarin AA, et al. Short-term study of allogeneic retinal pigment epithelium transplants onto debrided Bruch's membrane. Invest Ophthalmol Vis Sci. 2001;42:2990-2999. (Pubitemid 33035301)
55. De Clerck LS, Bridts CH, Mertens AM, Moens MM, Stevens WJ. Use of fluorescent dyes in the determination of adherence of human leucocytes to endothelial cells and the effect of fluorochromes on cellular function. J Immunol Methods. 1994;172:115-124.
56. Tanaka K, Koga Y, Taniguchi K, Kamikaseda K, Nomoto K. T cell recruitment from the thymus to the spleen in tumor-bearing mice. I. Analysis of recruited cells by surface markers. Cancer Immunol Immunother. 1986;22:37-42. (Pubitemid 16104504)
57. Wongpichedchai S, Weiter JJ, Weber P, Dorey CK. Comparison of external and internal approaches for transplantation of autologous retinal pigment epithelium. Invest Ophthalmol Vis Sci. 1992;33:3341-3352.
58. Sheedlo HJ, Li LX, Turner JE. Functional and structural characteristics of photoreceptor cells rescued in RPE-cell grafted retinas of RCS dystrophic rats. Exp Eye Res. 1989;48:841-854.
59. Thumann G, Aisenbrey S, Schraermeyer U, et al. Transplantation of autologous iris pigment epithelium after removal of choroidal neovascular membranes. Arch Ophthalmol. 2000;118:1350-1355. (Pubitemid 30775864)
60. Wen J, McKenna KC, Barron BC, Langston HP, Kapp JA. Use of superparamagnetic microbeads in tracking subretinal injections. Mol Vis. 2005;11:256-262. (Pubitemid 41358284)