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Volumn 628, Issue 2, 2008, Pages 204-213
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An accurate and precise high-performance liquid chromatography method for the rapid quantification of the novel HIV integrase inhibitor raltegravir in human blood plasma after solid phase extraction
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Author keywords
Antiretroviral agent; Chromatography; High performance liquid chromatography UV; Human immunodeficiency virus; Integrase inhibitor; Raltegravir; Solid phase extraction
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Indexed keywords
ACIDS;
BLOOD;
BODY FLUIDS;
CHROMATOGRAPHIC ANALYSIS;
CHROMATOGRAPHY;
HIGH PRESSURE LIQUID CHROMATOGRAPHY;
IONIC STRENGTH;
IONIZATION OF LIQUIDS;
LIQUID CHROMATOGRAPHY;
METHANOL;
OPTIMIZATION;
PLASMAS;
SOLAR RADIATION;
SOLVENT EXTRACTION;
ANTIRETROVIRAL AGENT;
HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY-UV;
HUMAN IMMUNODEFICIENCY VIRUS;
INTEGRASE INHIBITOR;
RALTEGRAVIR;
SOLID PHASE EXTRACTION;
EXTRACTION;
ANTILIPEMIC AGENT;
ANTIRETROVIRUS AGENT;
ATORVASTATIN;
DARUNAVIR;
DIAZEPAM;
EMTRICITABINE;
ENFUVIRTIDE;
ETRAVIRINE;
LAMIVUDINE;
PROTEINASE INHIBITOR;
RALTEGRAVIR;
RITONAVIR;
RNA DIRECTED DNA POLYMERASE INHIBITOR;
TENOFOVIR DISOPROXIL;
ZIDOVUDINE;
ACCURACY;
ANALYTIC METHOD;
ARTICLE;
BLOOD SAMPLING;
DRUG BLOOD LEVEL;
DRUG STABILITY;
DRUG STRUCTURE;
FEMALE;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HUMAN;
HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT;
HUMAN IMMUNODEFICIENCY VIRUS INFECTION;
LIQUID CHROMATOGRAPHY;
MALE;
PLASMA;
PRIORITY JOURNAL;
SOLID PHASE EXTRACTION;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
DRUG STABILITY;
HIV INTEGRASE INHIBITORS;
HUMANS;
PYRROLIDINONES;
REFERENCE STANDARDS;
REPRODUCIBILITY OF RESULTS;
SENSITIVITY AND SPECIFICITY;
SOLID PHASE EXTRACTION;
HUMAN IMMUNODEFICIENCY VIRUS;
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EID: 53149116234
PISSN: 00032670
EISSN: None
Source Type: Journal
DOI: 10.1016/j.aca.2008.09.007 Document Type: Article |
Times cited : (24)
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References (15)
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