Investigation of heat stress response in the camel fibroblast cell line Dubca

Annals of the New York Academy of Sciences

Volumn 1138, Issue , 2008, Pages 376-384

  Thayyullathil, Faisal ^a   Chathoth, Shahanas ^a   Hago, Abdulkader ^a   Wernery, Ulli ^b   Patel, Mahendra ^a   Galadari, Sehamuddin ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^b CENTRAL VETERINARY RESEARCH LABORATORY   (United Arab Emirates)

Author keywords

Akt; c Jun; Camel fibroblast; Cell line Dubca; Heat stress; Heat shock protein; Jnk

Indexed keywords

HEAT SHOCK PROTEIN 70; PROTEIN C JUN; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; CAMEL; CELL GROWTH; CELL SURVIVAL; CONFERENCE PAPER; CYTOTOXICITY; DOWN REGULATION; DUBCA CELL; ENZYME REPRESSION; FIBROBLAST; FIBROBLAST CULTURE; HEAT SHOCK; HEAT STRESS; NEOPLASM; NITROBLUE TETRAZOLIUM TEST; NONHUMAN; PHENOTYPE; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; TEMPERATURE; WESTERN BLOTTING;

EID: 53149113838     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1414.039     Document Type: Conference Paper

References (16)

1. Gabai, V.L. & M.Y. Sherman. 2002. Molecular biology of thermoregulation: interplay between molecular chaperones and signaling pathways in survival of heat shock. J. Appl. Physiol. 92 : 1743 1748.
2. Schmidt-Nilsen, K. 1972. Animals of the Deserts, pp 308 310. Nauka. Moscow.
3. Lindquist, S. 1986. The heat-shock response. Ann. Rev. Biochem. 55 : 1151 1191.
4. Nadeau, S.I. & J. Landry. 2007. Mechanism of activation and regulation of the heat shock-sensitive signaling pathways. In Molecular Aspects of the Stress Response; Chaperones, Membranes and Networks. P. Csermely & L. Vigh, Eds Chapter 10, 100 113. Springer. Berlin, Germany.
5. Nicholson, K.M. & N.G. Anderson. 2002. The Akt/PKB signaling pathway in human malignancy. Cell Signal. 14 : 381 395.
6. Burgering, B.M. & P.J. Coffer. 1995. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376 : 599 602.
7. Brazil, D.P. & B.A. Hemmings. 2001. Ten years of protein kinase B signaling: a hard Akt to follow. Trends Biochem. Sci. 26 : 657 664.
8. Kyriakis, J.M., P. Banerjee, E. Nikolakaki, et al. 1994. The stress-activated protein kinase subfamily of c-Jun kinases. Nature 369 : 156 160.
9. Sluss, H.K., T. Barrett, B. Dérijard, et al. 1994. Signal transduction by tumour necrosis factor mediated by JNK protein kinases. Mol. Cell. Biol. 14 : 8376 8384.
10. Enomoto, A., N. Suzuki, C. Liu, et al. 2001. Involvement of c-Jun NH2-terminal kinase 1 in heat-induced apoptotic cell death of human monoblastic leukaemia U937 cells. Int. J. Radiat. Biol. 77 : 867 874.
11. Deng, Y., X. Ren, L. Yang, et al. 2003. Jnk-dependent pathway is required for TNFα-induced apoptosis. Cell 115 : 61 70.
12. Denizot, F. & R. Lang. 1986. Rapid colorimetric assay for cell growth and survival: modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J. Immunol. Methods 89 : 271 277.
13. Gabai, V.L., J.A. Yaglom, V. Volloch, et al. 2000. Hsp72-Mediated suppression of c-Jun N-terminal kinase is implicated in development of tolerance to caspase-independent cell death. Mol. Cell Biol. 20 : 6826 6836.
14. Galadari, S., F. Thayyullathil, A. Hago, et al. 2008. Akt depletion is an important determinant of L929 cell death following heat stress. Ann. N. Y. Acad Sci. Recent Advances in Clinical Oncology. In press.
15. Gabai, V.L., I.V. Zamulaeva, A.F. Mosin, et al. 1995. Resistance of Ehrlich tumor cells to apoptosis can be due to accumulation of heat shock proteins. FEBS Lett. 375 : 21 26.
16. Gabai, V.L., A.B. Meriin, J.A. Yaglom, et al. 1998. Role of Hsp70 in regulation of stress-kinase JNK: implication in apoptosis and aging. FEBS Lett. 438 : 1 4.