Synthesis and biological activities of some new fluorinated coumarins and 1-aza coumarins

European Journal of Medicinal Chemistry

Volumn 43, Issue 10, 2008, Pages 2178-2188

  Kalkhambkar, Rajesh G ^a   Kulkarni, Geeta M ^a   Kamanavalli, Chandrappa M ^a   Premkumar, N ^b   Asdaq, S M B ^b   Sun, Chung Ming ^c  

^a KARNATAK UNIVERSITY   (India)

^b KRUPANIDHI COLLEGE OF PHARMACY   (India)

^c NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

Author keywords

Analgesic; Anti bacterial; Anti fungal; Anti inflammatory; Fluorinated 1 aza coumarin; Fluorinated coumarin

Indexed keywords

4 [(4' FLUORO)PHENOXYMETHYL] 1 AZACOUMARIN; 5,6 BENZO 4 [(4' FLUORO)ANILINOMETHYL]COUMARIN; 6 CHLORO 4 [(4' FLUORO)ANILINOMETHYL]COUMARIN; 6 CHLORO 4 [(4' FLUORO)PHENOXYMETHYL] 1 AZACOUMARIN; 6 CHLORO 4 [(4' FLUORO)PHENOXYMETHYL]COUMARIN; 6 METHYL 4 [(4' FLUORO)PHENOXYMETHYL]COUMARIN; 7 CHLORO 4 [(4' CHLORO)PHENOXYMETHYL] 1 AZACOUMARIN; 7 CHLORO 4 [(4' FLUORO)ANILINOMETHYL] 1 AZACOUMARIN; 7 METHYL 4 [(4' FLUORO)ANILINOMETHYL]COUMARIN; 7,8 BENZO 4 [(4' FLUORO)PHENOXYMETHYL]COUMARIN; 8 METHYL 4 [(4' FLUORO)ANILINOMETHYL] 1 AZACOUMARIN; COUMARIN DERIVATIVE; FLUORINATED 1 AZACOUMARIN; FLUORINATED COUMARIN; INDOMETACIN; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; ASPERGILLUS NIGER; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; FEMALE; LD 50; MALE; MOUSE; NONHUMAN; PAW EDEMA; RAT; ULCEROGENESIS;

ANALGESICS; ANIMALS; AZA COMPOUNDS; BACTERIA; COUMARINS; DRUG DESIGN; FLUORINE; FUNGI; INFLAMMATION; MICE;

EID: 53149111148     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.08.007     Document Type: Article

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