Pig to Canine Auxiliary Hepatic Xenotransplantation Model: Prevention of Hyperacute Rejection Via Kupffer Cell Blockade and Complement Regulation

Transplantation Proceedings

Volumn 40, Issue 8, 2008, Pages 2755-2759

  Chung, K Y ^a   Park, J J ^a   Han, K H ^a  

^a Ewha Womans University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; ALBUMIN; COBROTOXIN; COMPLEMENT; CREATININE; FIBRIN; FIBRINOGEN; GADOLINIUM; GADOLINIUM TRICHLORIDE; HISTIDINE; PROTEIN; TRYPTOPHAN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUXILIARY HEPATIC XENOTRANSPLANTATION; BLEEDING; BLOOD SAMPLING; CELL DEATH; CELL VACUOLE; CONTROLLED STUDY; DOG; FEMALE; FIBRIN DEPOSITION; HEPATIC ARTERY; HYPERACUTE GRAFT REJECTION; INTERSTITIAL HEMORRHAGE; KIDNEY PARENCHYMA; KUPFFER CELL; LIVER; LIVER VEIN; LUNG PARENCHYMA; MALE; MICROSCOPY; NEUTROPHIL; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PORTAL VEIN; PRIORITY JOURNAL; PROTHROMBIN TIME; REPERFUSION; SWINE; THROMBOCYTE COUNT; UREA NITROGEN BLOOD LEVEL; XENOTRANSPLANTATION;

ACUTE DISEASE; ANIMALS; COBRA VENOMS; COMPLEMENT SYSTEM PROTEINS; DISEASE MODELS, ANIMAL; DOGS; FEMALE; GADOLINIUM; GRAFT REJECTION; HEPATIC ARTERY; KUPFFER CELLS; LIVER TRANSPLANTATION; MALE; NECROSIS; PORTAL VEIN; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 53149101692     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2008.08.056     Document Type: Article

References (5)

1. Byrne G., McCurry K., Martin M., et al. Transgenic pigs expressing human CD59 and decay accelerating factor produce an intrinsic barrier to complement-mediated damage. Transplantation 63 (1997) 149
2. Cozzi E., Tucker A.W., Langford G.A., et al. Characterization of pigs transgenic for human decay- accelerating factor. Transplantation 64 (1997) 1383
3. Lin S.S., Hanaway M.J., Gonzalez S.G., et al. The role of anti-Gal(alpha1-3)Gal antibodies in acute vascular rejection and accommodation of xenografts. Transplantation 70 (2000) 1667
4. Loss M., Vangerow B., Schmidtko J., et al. Acute vascular rejection is associated with systemic complement activation in a pig-to-primate kidney xenograft model. Xenotransplantation 7 (2000) 186
5. Nakajima R., Nakajima S., Nagata S., et al. Analysis of hyperacute rejection in newborn pig to dog lung xenotransplantation. Transplant Proc 32 (2000) 1131