Mechanical properties of physiological and pathological models of collagen peptides investigated via steered molecular dynamics simulations

Journal of Biomechanics

Volumn 41, Issue 14, 2008, Pages 3073-3077

  Gautieri, Alfonso ^a   Vesentini, Simone ^a   Montevecchi, Franco M ^b   Redaelli, Alberto ^a  

^a POLITECNICO DI MILANO   (Italy)

^b POLITECNICO DI TORINO   (Italy)

Author keywords

Collagen; Disease associated mutation; Mechanical properties; Molecular modelling; Osteogenesis imperfecta

Indexed keywords

AMINES; COLLAGEN; DYNAMICS; ELASTIC MODULI; ELASTICITY; HYDROGEN; HYDROGEN BONDS; HYDROPHOBICITY; MECHANICAL PROPERTIES; MOLECULAR DYNAMICS; PEPTIDES; PROTEINS; QUANTUM CHEMISTRY;

ALANINE SUBSTITUTION; COLLAGEN FIBRILS; COLLAGEN PEPTIDES; COLLAGEN TYPE I; DISEASE-ASSOCIATED MUTATION; ELASTIC PROPERTIES; FIRST PRINCIPLES; HETEROTRIMER; HOMOTRIMER; HYDROPHOBIC INTERACTIONS; IDEAL MODEL; MOLECULAR MODELLING; MOLECULAR SIMULATIONS; OSTEOGENESIS IMPERFECTA; SINGLE CHAINS; STEERED MOLECULAR DYNAMICS SIMULATIONS; TRIPLE HELIXES; YOUNG'S MODULUS;

PHYSIOLOGICAL MODELS;

ALANINE; COLLAGEN; COLLAGEN TYPE 1; GLYCINE;

AMINO ACID SUBSTITUTION; ARTICLE; ELASTICITY; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR MODEL; OSTEOGENESIS IMPERFECTA; PRIORITY JOURNAL; PROTEIN STRUCTURE; TRIPLE HELIX;

ANIMALS; COLLAGEN; ELASTIC MODULUS; HUMANS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MODELS, MOLECULAR; OSTEOGENESIS IMPERFECTA; PEPTIDES; STRESS, MECHANICAL;

EID: 53149100799     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2008.06.028     Document Type: Article

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