-
1
-
-
33344461287
-
Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
-
10.1056/NEJMoa052771. 16495392
-
Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. DO Clegg DJ Reda CL Harris MA Klein JR O'Dell MM Hooper JD Bradley CO Bingham 3rd MH Weisman CG Jackson, N Engl J Med 2006 354 8 795 808 10.1056/NEJMoa052771 16495392
-
(2006)
N Engl J Med
, vol.354
, Issue.8
, pp. 795-808
-
-
Clegg, D.O.1
Reda, D.J.2
Harris, C.L.3
Klein, M.A.4
O'Dell, J.R.5
Hooper, M.M.6
Bradley, J.D.7
Bingham III, C.O.8
Weisman, M.H.9
Jackson, C.G.10
-
2
-
-
0035956653
-
Long-term effects of glucosamine sulphate on osteoarthritis progression: A randomised, placebo-controlled clinical trial
-
10.1016/S0140-6736(00)03610-2. 11214126
-
Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial. JY Reginster R Deroisy LC Rovati RL Lee E Lejeune O Bruyere G Giacovelli Y Henrotin JE Dacre C Gossett, Lancet 2001 357 9252 251 256 10.1016/S0140-6736(00)03610-2 11214126
-
(2001)
Lancet
, vol.357
, Issue.9252
, pp. 251-256
-
-
Reginster, J.Y.1
Deroisy, R.2
Rovati, L.C.3
Lee, R.L.4
Lejeune, E.5
Bruyere, O.6
Giacovelli, G.7
Henrotin, Y.8
Dacre, J.E.9
Gossett, C.10
-
3
-
-
0037078298
-
Glucosamine sulfate use and delay of progression of knee osteoarthritis: A 3-year, randomized, placebo-controlled, double-blind study
-
10.1001/archinte.162.18.2113. 12374520
-
Glucosamine sulfate use and delay of progression of knee osteoarthritis: a 3-year, randomized, placebo-controlled, double-blind study. K Pavelka J Gatterova M Olejarova S Machacek G Giacovelli LC Rovati, Arch Intern Med 2002 162 18 2113 2123 10.1001/archinte.162.18.2113 12374520
-
(2002)
Arch Intern Med
, vol.162
, Issue.18
, pp. 2113-2123
-
-
Pavelka, K.1
Gatterova, J.2
Olejarova, M.3
MacHacek, S.4
Giacovelli, G.5
Rovati, L.C.6
-
5
-
-
33644666907
-
Glucosamine decreases expression of anabolic and catabolic genes in human osteoarthritic cartilage explants
-
10.1016/j.joca.2005.10.001. 16300972
-
Glucosamine decreases expression of anabolic and catabolic genes in human osteoarthritic cartilage explants. EJ Uitterlinden H Jahr JL Koevoet YM Jenniskens SM Bierma-Zeinstra J Degroot JA Verhaar H Weinans GJ van Osch, Osteoarthritis Cartilage 2006 14 3 250 257 10.1016/j.joca.2005.10.001 16300972
-
(2006)
Osteoarthritis Cartilage
, vol.14
, Issue.3
, pp. 250-257
-
-
Uitterlinden, E.J.1
Jahr, H.2
Koevoet, J.L.3
Jenniskens, Y.M.4
Bierma-Zeinstra, S.M.5
Degroot, J.6
Verhaar, J.A.7
Weinans, H.8
Van Osch, G.J.9
-
6
-
-
3543044391
-
Fibroblast growth factor-2 in serum-free medium is a potent mitogen and reduces dedifferentiation of human ear chondrocytes in monolayer culture
-
10.1016/j.matbio.2004.06.004. 15296937
-
Fibroblast growth factor-2 in serum-free medium is a potent mitogen and reduces dedifferentiation of human ear chondrocytes in monolayer culture. EW Mandl H Jahr JL Koevoet JP van Leeuwen H Weinans JA Verhaar GJ van Osch, Matrix Biol 2004 23 4 231 241 10.1016/j.matbio.2004.06.004 15296937
-
(2004)
Matrix Biol
, vol.23
, Issue.4
, pp. 231-241
-
-
Mandl, E.W.1
Jahr, H.2
Koevoet, J.L.3
Van Leeuwen, J.P.4
Weinans, H.5
Verhaar, J.A.6
Van Osch, G.J.7
-
7
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
10.1006/meth.2001.1262. 11846609
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. KJ Livak TD Schmittgen, Methods 2001 25 4 402 408 10.1006/meth.2001.1262 11846609
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
8
-
-
0036726363
-
Inhibition of articular cartilage degradation by glucosamine-HCl and chondroitin sulphate
-
12405691
-
Inhibition of articular cartilage degradation by glucosamine-HCl and chondroitin sulphate. MW Orth TL Peters JN Hawkins, Equine Vet J Suppl 2002 34 224 229 12405691
-
(2002)
Equine Vet J Suppl
, Issue.34
, pp. 224-229
-
-
Orth, M.W.1
Peters, T.L.2
Hawkins, J.N.3
-
9
-
-
0038344684
-
Glucosamine sulfate modulates the levels of aggrecan and matrix metalloproteinase-3 synthesized by cultured human osteoarthritis articular chondrocytes
-
10.1016/S1063-4584(03)00052-9. 12801482
-
Glucosamine sulfate modulates the levels of aggrecan and matrix metalloproteinase-3 synthesized by cultured human osteoarthritis articular chondrocytes. GR Dodge SA Jimenez, Osteoarthritis Cartilage 2003 11 6 424 432 10.1016/S1063-4584(03)00052-9 12801482
-
(2003)
Osteoarthritis Cartilage
, vol.11
, Issue.6
, pp. 424-432
-
-
Dodge, G.R.1
Jimenez, S.A.2
-
10
-
-
0034745403
-
Interleukin-1beta down-regulates the expression of glucuronosyltransferase I, a key enzyme priming glycosaminoglycan biosynthesis: Influence of glucosamine on interleukin-1beta-mediated effects in rat chondrocytes
-
10.1002/1529-0131(200102)44:2<351::AID-ANR53>3.0.CO;2-M. 11229466
-
Interleukin-1beta down-regulates the expression of glucuronosyltransferase I, a key enzyme priming glycosaminoglycan biosynthesis: influence of glucosamine on interleukin-1beta-mediated effects in rat chondrocytes. JN Gouze K Bordji S Gulberti B Terlain P Netter J Magdalou S Fournel-Gigleux M Ouzzine, Arthritis Rheum 2001 44 2 351 360 10.1002/1529-0131(200102)44:2<351::AID-ANR53>3.0.CO;2-M 11229466
-
(2001)
Arthritis Rheum
, vol.44
, Issue.2
, pp. 351-360
-
-
Gouze, J.N.1
Bordji, K.2
Gulberti, S.3
Terlain, B.4
Netter, P.5
Magdalou, J.6
Fournel-Gigleux, S.7
Ouzzine, M.8
-
11
-
-
0032189902
-
Chondrocyte-mediated catabolism of aggrecan: Aggrecanase-dependent cleavage induced by interleukin-1 or retinoic acid can be inhibited by glucosamine
-
9742213
-
Chondrocyte-mediated catabolism of aggrecan: aggrecanase-dependent cleavage induced by interleukin-1 or retinoic acid can be inhibited by glucosamine. JD Sandy D Gamett V Thompson C Verscharen, Biochem J 1998 335 Pt 1 59 66 9742213
-
(1998)
Biochem J
, vol.335
, Issue.PART 1
, pp. 59-66
-
-
Sandy, J.D.1
Gamett, D.2
Thompson, V.3
Verscharen, C.4
-
13
-
-
0037501113
-
Influence of glucosamine on matrix metalloproteinase expression and activity in lipopolysaccharide-stimulated equine chondrocytes
-
10.2460/ajvr.2003.64.666. 12828249
-
Influence of glucosamine on matrix metalloproteinase expression and activity in lipopolysaccharide-stimulated equine chondrocytes. CR Byron MW Orth PJ Venta JW Lloyd JP Caron, Am J Vet Res 2003 64 6 666 671 10.2460/ajvr.2003.64. 666 12828249
-
(2003)
Am J Vet Res
, vol.64
, Issue.6
, pp. 666-671
-
-
Byron, C.R.1
Orth, M.W.2
Venta, P.J.3
Lloyd, J.W.4
Caron, J.P.5
-
14
-
-
0032211837
-
Stimulation of proteoglycan production by glucosamine sulfate in chondrocytes isolated from human osteoarthritic articular cartilage in vitro
-
10.1053/joca.1998.0146. 10343776
-
Stimulation of proteoglycan production by glucosamine sulfate in chondrocytes isolated from human osteoarthritic articular cartilage in vitro. C Bassleer L Rovati P Franchimont, Osteoarthritis Cartilage 1998 6 6 427 434 10.1053/joca.1998.0146 10343776
-
(1998)
Osteoarthritis Cartilage
, vol.6
, Issue.6
, pp. 427-434
-
-
Bassleer, C.1
Rovati, L.2
Franchimont, P.3
-
15
-
-
0027076009
-
In-vitro evaluation of drugs proposed as chondroprotective agents
-
1300309
-
In-vitro evaluation of drugs proposed as chondroprotective agents. C Bassleer Y Henrotin P Franchimont, Int J Tissue React 1992 14 5 231 241 1300309
-
(1992)
Int J Tissue React
, vol.14
, Issue.5
, pp. 231-241
-
-
Bassleer, C.1
Henrotin, Y.2
Franchimont, P.3
-
16
-
-
0037766040
-
Glucosamine and chondroitin sulfate: Biological response modifiers of chondrocytes under simulated conditions of joint stress
-
10.1016/S1063-4584(03)00026-8. 12744939
-
Glucosamine and chondroitin sulfate: biological response modifiers of chondrocytes under simulated conditions of joint stress. L Lippiello, Osteoarthritis Cartilage 2003 11 5 335 342 10.1016/S1063-4584(03)00026-8 12744939
-
(2003)
Osteoarthritis Cartilage
, vol.11
, Issue.5
, pp. 335-342
-
-
Lippiello, L.1
-
17
-
-
0018115799
-
Articular cartilage pharmacology: I. in vitro studies on glucosamine and non steroidal antiinflammatory drugs
-
10.1016/S0031-6989(78)80054-X. 151283
-
Articular cartilage pharmacology: I. In vitro studies on glucosamine and non steroidal antiinflammatory drugs. RR Vidal y Plana D Bizzarri AL Rovati, Pharmacol Res Commun 1978 10 6 557 569 10.1016/S0031-6989(78)80054-X 151283
-
(1978)
Pharmacol Res Commun
, vol.10
, Issue.6
, pp. 557-569
-
-
Vidal Plana, Y.R.R.1
Bizzarri, D.2
Rovati, A.L.3
-
18
-
-
0031748965
-
Enhanced synovial production of hyaluronic acid may explain rapid clinical response to high-dose glucosamine in osteoarthritis
-
10.1016/S0306-9877(98)90272-9. 9710325
-
Enhanced synovial production of hyaluronic acid may explain rapid clinical response to high-dose glucosamine in osteoarthritis. MF McCarty, Med Hypotheses 1998 50 6 507 510 10.1016/S0306-9877(98)90272-9 9710325
-
(1998)
Med Hypotheses
, vol.50
, Issue.6
, pp. 507-510
-
-
McCarty, M.F.1
-
19
-
-
0033623802
-
Sulfated glycosaminoglycans and glucosamine may synergize in promoting synovial hyaluronic acid synthesis
-
10.1054/mehy.1999.0954. 10859690
-
Sulfated glycosaminoglycans and glucosamine may synergize in promoting synovial hyaluronic acid synthesis. MF McCarty AL Russell MP Seed, Med Hypotheses 2000 54 5 798 802 10.1054/mehy.1999.0954 10859690
-
(2000)
Med Hypotheses
, vol.54
, Issue.5
, pp. 798-802
-
-
McCarty, M.F.1
Russell, A.L.2
Seed, M.P.3
-
20
-
-
35648976694
-
Glucosamine reduces anabolic as well as catabolic processes in bovine chondrocytes cultured in alginate
-
10.1016/j.joca.2007.04.004. 17543549
-
Glucosamine reduces anabolic as well as catabolic processes in bovine chondrocytes cultured in alginate. EJ Uitterlinden H Jahr JL Koevoet SM Bierma-Zeinstra JA Verhaar H Weinans GJ van Osch, Osteoarthritis Cartilage 2007 15 11 1267 1274 10.1016/j.joca.2007.04.004 17543549
-
(2007)
Osteoarthritis Cartilage
, vol.15
, Issue.11
, pp. 1267-1274
-
-
Uitterlinden, E.J.1
Jahr, H.2
Koevoet, J.L.3
Bierma-Zeinstra, S.M.4
Verhaar, J.A.5
Weinans, H.6
Van Osch, G.J.7
-
21
-
-
0026623391
-
Hyaluronan
-
1563592
-
Hyaluronan. TC Laurent JR Fraser, Faseb J 1992 6 7 2397 2404 1563592
-
(1992)
Faseb J
, vol.6
, Issue.7
, pp. 2397-2404
-
-
Laurent, T.C.1
Fraser, J.R.2
-
22
-
-
0029989042
-
The structure and function of hyaluronan: An overview
-
10.1038/icb.1996.32. 8724014
-
The structure and function of hyaluronan: An overview. TC Laurent UB Laurent JR Fraser, Immunol Cell Biol 1996 74 2 A1 7 10.1038/icb.1996.32 8724014
-
(1996)
Immunol Cell Biol
, vol.74
, Issue.2
, pp. 1-7
-
-
Laurent, T.C.1
Laurent, U.B.2
Fraser, J.R.3
-
23
-
-
0022343146
-
Concentration and molecular weight of sodium hyaluronate in synovial fluid from patients with rheumatoid arthritis and other arthropathies
-
4083937. 10.1136/ard.44.12.817
-
Concentration and molecular weight of sodium hyaluronate in synovial fluid from patients with rheumatoid arthritis and other arthropathies. LB Dahl IM Dahl A Engstrom-Laurent K Granath, Ann Rheum Dis 1985 44 12 817 822 4083937 10.1136/ard.44.12.817
-
(1985)
Ann Rheum Dis
, vol.44
, Issue.12
, pp. 817-822
-
-
Dahl, L.B.1
Dahl, I.M.2
Engstrom-Laurent, A.3
Granath, K.4
-
24
-
-
34548414633
-
Rheological properties of synovial fluids
-
17538199
-
Rheological properties of synovial fluids. H Fam JT Bryant M Kontopoulou, Biorheology 2007 44 2 59 74 17538199
-
(2007)
Biorheology
, vol.44
, Issue.2
, pp. 59-74
-
-
Fam, H.1
Bryant, J.T.2
Kontopoulou, M.3
-
25
-
-
38049066579
-
Hyaluronan in Tissue Injury and Repair
-
10.1146/annurev.cellbio.23.090506.123337. 17506690
-
Hyaluronan in Tissue Injury and Repair. D Jiang J Liang PW Noble, Annu Rev Cell Dev Biol 2007 23 435 61 10.1146/annurev.cellbio.23.090506.123337 17506690
-
(2007)
Annu Rev Cell Dev Biol
, vol.23
, pp. 435-61
-
-
Jiang, D.1
Liang, J.2
Noble, P.W.3
-
26
-
-
33751190978
-
High molecular weight hyaluronic acid down-regulates the gene expression of osteoarthritis-associated cytokines and enzymes in fibroblast-like synoviocytes from patients with early osteoarthritis
-
10.1016/j.joca.2006.05.009. 16806998
-
High molecular weight hyaluronic acid down-regulates the gene expression of osteoarthritis-associated cytokines and enzymes in fibroblast-like synoviocytes from patients with early osteoarthritis. CT Wang YT Lin BL Chiang YH Lin SM Hou, Osteoarthritis Cartilage 2006 14 12 1237 1247 10.1016/j.joca.2006.05.009 16806998
-
(2006)
Osteoarthritis Cartilage
, vol.14
, Issue.12
, pp. 1237-1247
-
-
Wang, C.T.1
Lin, Y.T.2
Chiang, B.L.3
Lin, Y.H.4
Hou, S.M.5
-
27
-
-
0021245988
-
Hyaluronate is synthesized at plasma membranes
-
6743290
-
Hyaluronate is synthesized at plasma membranes. P Prehm, Biochem J 1984 220 2 597 600 6743290
-
(1984)
Biochem J
, vol.220
, Issue.2
, pp. 597-600
-
-
Prehm, P.1
-
28
-
-
0035865681
-
Differential regulation and expression of hyaluronan synthases in human articular chondrocytes, synovial cells and osteosarcoma cells
-
11171074. 10.1042/0264-6021:3540017
-
Differential regulation and expression of hyaluronan synthases in human articular chondrocytes, synovial cells and osteosarcoma cells. AD Recklies C White L Melching PJ Roughley, Biochem J 2001 354 Pt 1 17 24 11171074 10.1042/0264-6021:3540017
-
(2001)
Biochem J
, vol.354
, Issue.PART 1
, pp. 17-24
-
-
Recklies, A.D.1
White, C.2
Melching, L.3
Roughley, P.J.4
-
29
-
-
34250005110
-
Synovial and plasma glucosamine concentrations in osteoarthritic patients following oral crystalline glucosamine sulphate at therapeutic dose
-
10.1016/j.joca.2007.01.019. 17353133
-
Synovial and plasma glucosamine concentrations in osteoarthritic patients following oral crystalline glucosamine sulphate at therapeutic dose. S Persiani R Rotini G Trisolino LC Rovati M Locatelli D Paganini D Antonioli A Roda, Osteoarthritis Cartilage 2007 15 7 764 772 10.1016/j.joca.2007.01.019 17353133
-
(2007)
Osteoarthritis Cartilage
, vol.15
, Issue.7
, pp. 764-772
-
-
Persiani, S.1
Rotini, R.2
Trisolino, G.3
Rovati, L.C.4
Locatelli, M.5
Paganini, D.6
Antonioli, D.7
Roda, A.8
-
30
-
-
0034533188
-
The effects of glucosamine derivatives on equine articular cartilage degradation in explant culture
-
10.1053/joca.1999.0320. 11069729
-
The effects of glucosamine derivatives on equine articular cartilage degradation in explant culture. JI Fenton KA Chlebek-Brown TL Peters JP Caron MW Orth, Osteoarthritis Cartilage 2000 8 6 444 451 10.1053/joca.1999.0320 11069729
-
(2000)
Osteoarthritis Cartilage
, vol.8
, Issue.6
, pp. 444-451
-
-
Fenton, J.I.1
Chlebek-Brown, K.A.2
Peters, T.L.3
Caron, J.P.4
Orth, M.W.5
-
31
-
-
0036793172
-
High doses of glucosamine-HCl have detrimental effects on bovine articular cartilage explants cultured in vitro
-
10.1053/joca.2002.0834. 12359168
-
High doses of glucosamine-HCl have detrimental effects on bovine articular cartilage explants cultured in vitro. M de Mattei A Pellati M Pasello F de Terlizzi L Massari D Gemmati A Caruso, Osteoarthritis Cartilage 2002 10 10 816 825 10.1053/joca.2002.0834 12359168
-
(2002)
Osteoarthritis Cartilage
, vol.10
, Issue.10
, pp. 816-825
-
-
De Mattei, M.1
Pellati, A.2
Pasello, M.3
De Terlizzi, F.4
Massari, L.5
Gemmati, D.6
Caruso, A.7
-
32
-
-
0033858339
-
Glucosamine HCl reduces equine articular cartilage degradation in explant culture
-
10.1053/joca.1999.0299. 10903879
-
Glucosamine HCl reduces equine articular cartilage degradation in explant culture. JI Fenton KA Chlebek-Brown TL Peters JP Caron MW Orth, Osteoarthritis Cartilage 2000 8 4 258 265 10.1053/joca.1999.0299 10903879
-
(2000)
Osteoarthritis Cartilage
, vol.8
, Issue.4
, pp. 258-265
-
-
Fenton, J.I.1
Chlebek-Brown, K.A.2
Peters, T.L.3
Caron, J.P.4
Orth, M.W.5
-
33
-
-
0037116589
-
Glucosamine modulates IL-1-induced activation of rat chondrocytes at a receptor level, and by inhibiting the NF-kappa B pathway
-
10.1016/S0014-5793(01)03255-0. 11801247
-
Glucosamine modulates IL-1-induced activation of rat chondrocytes at a receptor level, and by inhibiting the NF-kappa B pathway. JN Gouze A Bianchi P Becuwe M Dauca P Netter J Magdalou B Terlain K Bordji, FEBS Lett 2002 510 3 166 170 10.1016/S0014-5793(01)03255-0 11801247
-
(2002)
FEBS Lett
, vol.510
, Issue.3
, pp. 166-170
-
-
Gouze, J.N.1
Bianchi, A.2
Becuwe, P.3
Dauca, M.4
Netter, P.5
Magdalou, J.6
Terlain, B.7
Bordji, K.8
-
34
-
-
5644270235
-
Comparison of inhibitory effects of glucosamine and mannosamine on bovine articular cartilage degradation in vitro
-
10.2460/ajvr.2004.65.1440. 15524333
-
Comparison of inhibitory effects of glucosamine and mannosamine on bovine articular cartilage degradation in vitro. DM Mello BD Nielsen TL Peters JP Caron MW Orth, Am J Vet Res 2004 65 10 1440 1445 10.2460/ajvr.2004.65.1440 15524333
-
(2004)
Am J Vet Res
, vol.65
, Issue.10
, pp. 1440-1445
-
-
Mello, D.M.1
Nielsen, B.D.2
Peters, T.L.3
Caron, J.P.4
Orth, M.W.5
-
35
-
-
0347517752
-
Effects of [3H]glucosamine concentration on [3H]chondroitin sulphate formation by cultured chondrocytes
-
12943531. 10.1042/BJ20030982
-
Effects of [3H]glucosamine concentration on [3H]chondroitin sulphate formation by cultured chondrocytes. PJ Mroz JE Silbert, Biochem J 2003 376 Pt 2 511 515 12943531 10.1042/BJ20030982
-
(2003)
Biochem J
, vol.376
, Issue.PART 2
, pp. 511-515
-
-
Mroz, P.J.1
Silbert, J.E.2
-
36
-
-
8444240454
-
Use of (3)H-glucosamine and (35)S-sulfate with cultured human chondrocytes to determine the effect of glucosamine concentration on formation of chondroitin sulfate
-
10.1002/art.20609. 15529373
-
Use of (3)H-glucosamine and (35)S-sulfate with cultured human chondrocytes to determine the effect of glucosamine concentration on formation of chondroitin sulfate. PJ Mroz JE Silbert, Arthritis Rheum 2004 50 11 3574 3579 10.1002/art.20609 15529373
-
(2004)
Arthritis Rheum
, vol.50
, Issue.11
, pp. 3574-3579
-
-
Mroz, P.J.1
Silbert, J.E.2
-
37
-
-
12344329227
-
Synovial fluid levels and serum pharmacokinetics in a large animal model following treatment with oral glucosamine at clinically relevant doses
-
10.1002/art.20762. 15641100
-
Synovial fluid levels and serum pharmacokinetics in a large animal model following treatment with oral glucosamine at clinically relevant doses. S Laverty JD Sandy C Celeste P Vachon JF Marier AH Plaas, Arthritis Rheum 2005 52 1 181 191 10.1002/art.20762 15641100
-
(2005)
Arthritis Rheum
, vol.52
, Issue.1
, pp. 181-191
-
-
Laverty, S.1
Sandy, J.D.2
Celeste, C.3
Vachon, P.4
Marier, J.F.5
Plaas, A.H.6
|