Role of placebo factors in clinical trials with special focus on enrichment designs

Pain

Volumn 139, Issue 2, 2008, Pages 479-480

  Staud, Roland ^a   Price, Donald D ^b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; PLACEBO; PREGABALIN;

ANALGESIA; CLINICAL TRIAL; DIZZINESS; DRUG DOSE TITRATION; DRUG EFFICACY; FIBROMYALGIA; HUMAN; LETTER; METHODOLOGY; NEUROPATHIC PAIN; PAIN; PLACEBO EFFECT; PRIORITY JOURNAL; SOMNOLENCE; VALIDATION STUDY;

EID: 53049105499     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2008.07.027     Document Type: Letter

References (7)

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2. Crofford L.J., Rowbotham M.C., Mease P.J., Russell I.J., Dworkin R.H., Corbin A.E., et al. Pregabalin for the treatment of fibromyalgia syndrome: results of a randomized, double-blind, placebo-controlled trial. Arthritis Rheum 52 (2005) 1264-1273
3. Price D.D., Finniss D.G., and Benedetti F. A comprehensive review of the placebo effect: recent advances and current thought. Annu Rev Psychol 59 (2008) 565-590
4. Staud R., and Price D.D. Long-term trials of pregabalin and duloxetine for fibromyalgia symptoms: how study designs can affect placebo factors. Pain 136 (2008) 232-234
5. Straube S., Derry S., McQuay H.J., and Moore R.A. Enriched enrolment: definition and effects of enrichment and dose in trials of pregabalin and gabapentin in neuropathic pain. A systematic review. Br J Clin Pharmacol 66 (2008) 266-275
6. Vase L., Riley J.L., and Price D.D. A comparison of placebo effects in clinical analgesic trials versus studies of placebo analgesia. Pain 99 (2002) 443-452
7. Vase L., Robinson M.E., Verne G.N., and Price D.D. The contributions of suggestion, desire, and expectation to placebo effects in irritable bowel syndrome patients - an empirical investigation. Pain 105 (2003) 17-25