Ligand-based virtual screening to identify new T-type calcium channel blockers

Channels

Volumn 1, Issue 4, 2007, Pages 300-304

  Ijjaali, Ismail ^a   Barrere, Christian ^b,c,d   Nargeot, Joel ^b,c,d   Petitet, François ^a   Bourinet, Emmanuel ^b,c,d  

^a Aureus Pharma   (France)

^b INSTITUT DE GÉNOMIQUE FONCTIONNELLE   (France)

^c CNRS UMR5203   (France)

^d UNIV MONTPELLIER   (France)

Author keywords

2D pharmacophore; CaV32; Epilepsy; Pain; T type calcium channel blockers; Virtual screening

Indexed keywords

CACNA1H PROTEIN, HUMAN; CALCIUM CHANNEL T TYPE; LIGAND;

ANIMAL; ARTICLE; CELL LINE; CELL MEMBRANE POTENTIAL; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER AIDED DESIGN; COMPUTER INTERFACE; DRUG DESIGN; DRUG EFFECT; FACTUAL DATABASE; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; NERVE CELL; REPRODUCIBILITY; STRUCTURE ACTIVITY RELATION;

ANIMALS; CALCIUM CHANNELS, T-TYPE; CELL LINE; COMPUTER-AIDED DESIGN; DATABASES, FACTUAL; DRUG DESIGN; HUMANS; LIGANDS; MEMBRANE POTENTIALS; MOLECULAR STRUCTURE; NEURONS; REPRODUCIBILITY OF RESULTS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; USER-COMPUTER INTERFACE;

EID: 53049100972     PISSN: 19336950     EISSN: 19336969     Source Type: Journal    
DOI: 10.4161/chan.4999     Document Type: Article

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