Clevidipine (Cleviprex) for IV treatment of severe hypertension

Medical Letter on Drugs and Therapeutics

Volumn 50, Issue 1295, 2008, Pages 73-74

[No Author Info available]

Author keywords

[No Author keywords available]

Indexed keywords

CLEVIDIPINE; CLEVIPREX; ESMOLOL; FENOLDOPAM MESILATE; GLYCERYL TRINITRATE; HYDRALAZINE; LABETALOL; NICARDIPINE; NITROPRUSSIDE SODIUM; PHENTOLAMINE; UNCLASSIFIED DRUG; ANTIHYPERTENSIVE AGENT; CALCIUM CHANNEL BLOCKING AGENT; PYRIDINE DERIVATIVE; VASODILATOR AGENT;

ACUTE KIDNEY FAILURE; ANGINA PECTORIS; AORTA DISSECTION; BRADYCARDIA; CARDIOGENIC SHOCK; CLINICAL TRIAL; CYANIDE POISONING; DISEASE SEVERITY; DRUG COST; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG EXCRETION; DRUG HALF LIFE; DRUG INDICATION; DRUG MARKETING; DRUG METABOLISM; DRUG SAFETY; DRUG TOXICITY; EMERGENCY WARD; FOOD AND DRUG ADMINISTRATION; HEART ATRIUM FIBRILLATION; HEART BLOCK; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART SURGERY; HUMAN; HYPERTENSION; HYPERTENSIVE CRISIS; HYPOTENSION; INTENSIVE CARE UNIT; INTRAOCULAR PRESSURE; ISOTOPE LABELING; OPERATING ROOM; PERIOPERATIVE PERIOD; PHEOCHROMOCYTOMA; SHORT SURVEY; SIDE EFFECT; SYSTOLIC BLOOD PRESSURE; TACHYCARDIA; TREATMENT FAILURE; ARTICLE; BLOOD PRESSURE; DRUG EFFECT; EMERGENCY TREATMENT; HOSPITALIZATION; INTRAVENOUS DRUG ADMINISTRATION; PATHOPHYSIOLOGY; TREATMENT OUTCOME;

ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CALCIUM CHANNEL BLOCKERS; DRUG COSTS; EMERGENCY TREATMENT; HUMANS; HYPERTENSION; INFUSIONS, INTRAVENOUS; PYRIDINES; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME; VASODILATOR AGENTS;

EID: 53049100232     PISSN: 0025732X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (7)

1. Cardiovascular Drugs in the ICU. Treat Guidel Med Lett 2002; 1:19.
2. J Varon. Treatment of acute severe hypertension: current and newer agents. Drugs 2008; 68:283.
3. M Nordlander et al. Pharmacodynamic, pharmacokinetic and clinical effects of clevidipine, an ultrashort-acting calcium antagonist for rapid blood pressure control. Cardiovasc Drug Rev 2004; 22:227.
4. JH Levy et al. Clevidipine effectively and rapidly controls blood pressure preoperatively in cardiac surgery patients: the results of the randomized, placebo-controlled efficacy study of clevidipine assessing its preoperative antihypertensive effect in cardiac surgery-1 (ESCAPE-1). Anesth Analg 2007; 105:918.
5. N Singla et al. Treatment of acute postoperative hypertension in cardiac surgery patients: an efficacy study of clevidipine assessing its postoperative antihypertensive effect in cardiac surgery-2 (ESCAPE-2), a randomized, double-blind, placebo-controlled trial. Anesth Analg 2008; 107:59.
6. CV Pollack et al. Clevidipine, an intravenous dihydropyridine calcium channel blocker, is safe and effective for the treatment of patients with acute severe hypertension. Ann Emerg Med 2008; June 4 epub ahead of print.
7. S Aronson et al. The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients. Anesth Analg 2008; 107:1111.